Protein Alignment GBP3 and si:dkeyp-30d6.2

DIOPT Version :10

• Sequence 1: NP_060754.2
• Gene: GBP3 / 2635
• HGNCID: 4184
• Length: 595
• Species: Homo sapiens
• Sequence 2: NP_001353308.1
• Gene: si:dkeyp-30d6.2 / 100322630
• ZFINID: ZDB-GENE-141222-83
• Length: 378
• Species: Danio rerio
• Alignment Length: 375
• Identity: 201/375 - (53%)
• Similarity: 264/375 - (70%)
• Gaps: 7/375 - (1%)

Human     7 MTGPMCLIE-NTNGELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFSLGST 70
            |..|:|||. :::|:|...|.||::|..|.|||||||:|||||||||||||.||||..||:||.|
Zfish     1 MDKPVCLINTDSDGKLYVQPAALQVLQQIQQPVVVVAVVGLYRTGKSYLMNHLAGKQTGFALGGT 65

Human    71 VKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTLVYNSMGTIN 135
            ::|.||||||||||||.|...|||||||||||||:|||:::|:.||.|||||||||||||.||||
Zfish    66 IESKTKGIWMWCVPHPTKTGTTLVLLDTEGLGDVEKGDSKHDTNIFCLAVLLSSTLVYNSRGTIN 130

Human   136 QQAMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPDEYL 200
            .:|:::|.||||||..|:.|||  :.:.:||.:||.|||.|:|::|||:|:.:.||:..|.||||
Zfish   131 NRAIEELQYVTELTECIKVKSS--DEDVDDSTEFVKFFPSFIWSVRDFTLERKIDGKDATEDEYL 193

Human   201 EYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRKLAQLEKLQDEELDPEFVQQVA 265
            |::|||..|||:|..:|||||.||:||||.:.||.|..|....|::.||.|...:|..||::...
Zfish   194 EFALKLKPGTSKKITSFNLPRECIQKFFPTRTCFTFPFPTAPEKMSTLESLSPADLSTEFLEVTK 258

Human   266 DFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYINAISRGDLPCMENAVLALAQIENSAAVQKAI 330
            .||.::|..|:.|.|..|..|.|..|.:|...|:|.||.|.:||:||||:|:|||||.||.|:.:
Zfish   259 RFCKFVFDKSEVKRLKDGHTVTGRVLGNLTKMYVNTISSGAVPCLENAVIAMAQIENVAATQEGL 323

Human   331 AHYDQQMGQ-KVQLPAETLQELLDLHRVSEREATEVYMKNSFKDVD--HL 377
            ..|.:.|.: |...|.| |:::...|:....:||:.:|..||||.|  ||
Zfish   324 EVYQRGMEKVKCSFPLE-LEQVSSEHQRLSSKATQAFMARSFKDTDGKHL 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBP3	NP_060754.2	GTPase domain (Globular). /evidence=ECO:0000250|UniProtKB:P32455	1..309		169/302 (56%)
		GBP	18..280	CDD:460516	153/261 (59%)
		GBP_C	282..574	CDD:460721	42/99 (42%)
si:dkeyp-30d6.2	NP_001353308.1	GBP	13..273	CDD:460516	153/261 (59%)
		GBP_C	281..>376	CDD:293879	40/93 (43%)