Protein Alignment GBP2 and mto1

DIOPT Version :9

• Sequence 1: NP_004111.2
• Gene: GBP2 / 2634
• HGNCID: 4183
• Length: 591
• Species: Homo sapiens
• Sequence 2: NP_588284.1
• Gene: mto1 / 2539467
• PomBaseID: SPCC417.07c
• Length: 1115
• Species: Schizosaccharomyces pombe
• Alignment Length: 604
• Identity: 130/604 - (21%)
• Similarity: 229/604 - (37%)
• Gaps: 173/604 - (28%)

Human    90 EHTLVLLDTEGLGDIEKGD---NENDSWIFALAILLSSTF------VYNSMGTINQQAMDQLHYV 145
            |..:..|.||...:|||.:   .||:..|        |.|      :.:.:..::::..|:.|..
pombe   566 EEVVGKLRTEAEREIEKFEKTIRENEESI--------SLFKEEVEKLTDEITQLSERYNDKCHEF 622

Human   146 TELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTL-ELEVDG-EPITADDYLELSLK--- 205
            .||..|::......|.:.:||....|..      |....: |.|||. .....::...::||
pombe   623 DELQKRLQTLEEENNKAKEDSTSKTSNL------LEQLKMTEAEVDSLRKENEENKQVIALKESE 681

Human   206 LRKGTDKK------SKSFNDPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELNPDFIEQV 264
            |.|..|.|      .:|.||.   :.:...:.:.......:...||::|::...:||: ...:::
pombe   682 LVKSNDNKLLLNEQIESLNDQ---LSQLKTEMESVTTSKESLADYLSNLKERHNDELD-SLNKKL 742

Human   265 AEFCSYILSHSNVKTLSGGIPVNGPRLESLVLTYVNAISSGDLPCMENAVL-------------- 315
            .||...:.|:|::|:          .:|.....||....:.|  .::||::
pombe   743 REFEGILSSNSSLKS----------EIEERNNQYVTLRENFD--SLQNAIMETFDKQVTHCSVNH 795

Human   316 ALAQI-----EN------SAAVEKAIAHYEQQMGQKV-QLPT-----ETLQELLDLHRDSEREAI 363
            .:.||     ||      :..:.|.|.|.||.:.:|. .|.|     :.|:.|||..|.| ::||
pombe   796 LVQQIRKLKDENKKDQSGTDKLMKKIYHCEQSLKEKTNSLETLVSEKKELKNLLDAERRS-KKAI 859

Human   364 EVFMKNSFKDVDQMFQRKLGAQLEARRDDFCKQNSKASSDCCMALLQDIFGPLEEDVKQ------ 422
            ::.::|.   ..|.|:|.|...         ...|:.|....:.|||.....|:|.|::
pombe   860 QLELENL---SSQAFRRNLSGS---------SSPSERSQSRELKLLQASEKRLKEQVEERNSLIK 912

Human   423 ---------GTFSKP-------------------GGYRLFTQKLQELKNKYYQVPRKGIQAKEVL 459
                     .|.|||                   ..:|...:.:||.|.|...:.|   :.|..|
pombe   913 NIVTRFTQLNTGSKPVNTNVEALTTISSMNQAVNMNFRELDKSIQEFKRKCQSMER---EFKTEL 974

Human   460 KKYLESKEDVADALLQT-DQSLSEKEKAIEVERIK----------AESAEAAKKM-LEEIQKK-- 510
            :|        .|.:|:. .:.||:.|     ||:|          ..|..|:|:: |:...||
pombe   975 RK--------LDGVLEARSKRLSQLE-----ERVKLLGAGSTSSIPNSPRASKRVSLDSEDKKLV 1026

Human   511 ----NEEMME------QKEKSYQEHVKQLTEKMERDRAQLMAEQEKTLALKLQEQERLLKEGFEN 565
                ::..::      :::.....|:.||  ::.....||.||||.....||..:|||  :....
pombe  1027 PASPDKSAVQRGITALKRDAEGMSHIWQL--RLREMEFQLKAEQEGRKRDKLGARERL--QDLIR 1087

Human   566 ESKRLQKDI-WDIQMRSKS 583
            :::.|.:.| .|.:..|:|
pombe  1088 QNRSLSRQIKTDKESNSRS 1106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBP2	NP_004111.2	GTPase domain (Globular). /evidence=ECO:0000250	1..309		49/238 (21%)
		GBP	18..280	CDD:308078	45/209 (22%)
		GBP_C	282..578	CDD:308475	83/385 (22%)
mto1	NP_588284.1	Cnn_1N	252..319	CDD:285263
		Fib_alpha	511..611	CDD:285864	12/52 (23%)
		Mto2_bdg	1052..1101	CDD:289572	16/52 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000