Protein Alignment GBP2 and atln-2

DIOPT Version :9

• Sequence 1: NP_004111.2
• Gene: GBP2 / 2634
• HGNCID: 4183
• Length: 591
• Species: Homo sapiens
• Sequence 2: NP_502809.2
• Gene: atln-2 / 189829
• WormBaseID: WBGene00012763
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 457
• Identity: 96/457 - (21%)
• Similarity: 183/457 - (40%)
• Gaps: 84/457 - (18%)

Human     1 MAPEINLPGPMSLIDNTKGQLVVNPEALKIL----SAITQPVVVVAIVGLYRTGKSYLMNKLAG- 60
            :||....||...|          |..||..:    :...:.:|::::.|.:|.|||:|:|....
 Worm    33 IAPSSTQPGKFRL----------NESALNSVLGHSACANKKIVIISVAGAFRKGKSFLLNFFLEY 87

Human    61 ---------------------KKNGFSLGSTVKSHTKGIWMWCVP----HPKKPEHTLVLLDTEG 100
                                 :.:||...:.||..|.|||:|..|    ........:||:||:|
 Worm    88 LYSLHKSQQSDSSLEWLTDDCQLHGFHWRAGVKRDTVGIWLWGEPIMIESVTGEMFAVVLMDTQG 152

Human   101 LGDIEKGDNENDSW-----IFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTDRIKANSSPGN 160
            ..|      .|.::     :|||:.::||..:||.:..|.:.|:..|....|.          |.
 Worm   153 TFD------NNSTYQQCMTVFALSTIVSSVQIYNVVDNIQEDALQHLSLFVEY----------GR 201

Human   161 NSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIR 225
            .:::...:|...|...|:.:|||..:.|.:.......|:|:..|:.   ..::.:.....|..:|
 Worm   202 IAMEQPHNFGKPFQQLVFCVRDFKNQEEYEFGENGGTDFLDNVLQT---NPEQPEEIKQVRELLR 263

Human   226 KFFPKRKCFVFDWPAPK-----KYLAHLEQLKEEELNPDFIEQVAEFCSYILS-HSNVKTLSGGI 284
            ::|...:|::...|..|     .:..|:     ::|.|.|.|::.:....:|. |.....:..|.
 Worm   264 EYFEDIQCYLLPHPGYKVAERQSFRGHV-----KDLRPLFREELKKMVPNLLGPHILKPKIVNGK 323

Human   285 PVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVEKAIAHYEQQMGQK---VQLPTE 346
            .|...::......|..:.....||..::.:.|.|::....|..:|..:|.:.|.:.   .::.:|
 Worm   324 TVTCRKMIQYFKEYAASFDGETLPQPQSILNANAKLICIEAAHEAKVNYSRGMDRSTYGTRMMSE 388

Human   347 TLQELLDLHRDSEREAIEVFMK---NSFKDVDQMFQRKLGAQLEARRDDFCKQN-SKASSDCCMA 407
              ::||:.|......|:.:|.|   ...|:|..:...||...:.|..:.:.:.| :|..:.|..|
 Worm   389 --KKLLEAHIKHGITALNIFDKCPRIGAKEVRNLLLEKLQEDINAELEKYKRLNEAKRVTGCASA 451

Human   408 LL 409
            :|
 Worm   452 ML 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBP2	NP_004111.2	GTPase domain (Globular). /evidence=ECO:0000250	1..309		72/348 (21%)
		GBP	18..280	CDD:308078	63/302 (21%)
		GBP_C	282..578	CDD:308475	28/135 (21%)
atln-2	NP_502809.2	P-loop_NTPase	41..310	CDD:393306	63/302 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2037
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820