Protein Alignment GBP2 and atln-1

DIOPT Version :9

• Sequence 1: NP_004111.2
• Gene: GBP2 / 2634
• HGNCID: 4183
• Length: 591
• Species: Homo sapiens
• Sequence 2: NP_001023492.1
• Gene: atln-1 / 177059
• WormBaseID: WBGene00021868
• Length: 573
• Species: Caenorhabditis elegans
• Alignment Length: 439
• Identity: 108/439 - (24%)
• Similarity: 186/439 - (42%)
• Gaps: 77/439 - (17%)

Human    11 MSLIDNTKGQLVVNPEAL-KIL---SAITQPVVVVAIVGLYRTGKSYLMN-------------KL 58
            :.::::|.....:|.|.| |||   ....:.|.|:.:.|.||.|||:|:|             |:
 Worm    36 VEVVEDTDHSFELNTELLEKILLDPKVADKKVAVIGVAGAYRKGKSFLLNFFLRYLTWRSKADKV 100

Human    59 AGK--------------KNGFSLGSTVKSHTKGIWMWCVPHPKK----PEHTLVLLDTEGLGDIE 105
            .|:              .:|||.....:..|.||.:|..|...|    .|..::|:||:|..| .
 Worm   101 MGEVELDNSQWMSPNSPLSGFSWRGGSERDTNGILIWSEPFIMKDKNGEEIAVLLMDTQGAFD-S 164

Human   106 KGDNENDSWIFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTDRIKANSSPGNNSVDDSADFV 170
            :...::.:.||||:.::||..:||....|.:..:..|...||.          |..:::|||.
 Worm   165 QSTVKDCATIFALSTMISSVQIYNLSQNIQEDDLQHLQLFTEY----------GRLALEDSAS-- 217

Human   171 SFFPAFVWTLRDFTLELEVD----GEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKR 231
            ..|.:.::.:||::...|.:    |.....|..||:|       :|:.......|..||..|...
 Worm   218 KPFQSLLFLVRDWSFPYEAEFGFQGGQRVLDRRLEVS-------EKQHAELQQLRQHIRSCFEDI 275

Human   232 KCFVFDWPAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYIL-SHSNVKTLSGGIPVNGPRLESLV 295
            :||:...|..|.........|..::..:|.:|:......:| ||:.|..     .:||.::....
 Worm   276 RCFLMPHPGLKVATNPNFDGKLVDIENEFQQQLGVMIPRLLDSHALVHK-----EINGQKMTCRE 335

Human   296 L-----TYVNAISSGDLPCMENAVLALAQIENSAAVEKAIAHYEQQMGQKV--QLPTETLQELLD 353
            |     .|::.....|||..::.::|.|:..|.|||..|.|.|:::|.:..  ..|..:..|||:
 Worm   336 LLEYFKAYMHIFRGQDLPEPKSMLMATAEANNLAAVASARAVYQREMEEVCGGDTPYMSTNELLE 400

Human   354 LHRDSEREAIEVFMKNSFK----DVDQMFQRKLGAQLEARRDDFCKQNS 398
            .|...:..||..| :|:.|    |....|..:|.:.|:...:::.|.|:
 Worm   401 HHDRVKNIAIREF-RNARKMGGVDFSMQFLERLESDLQESYENYLKVNN 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBP2	NP_004111.2	GTPase domain (Globular). /evidence=ECO:0000250	1..309		81/342 (24%)
		GBP	18..280	CDD:308078	74/301 (25%)
		GBP_C	282..578	CDD:308475	33/128 (26%)
atln-1	NP_001023492.1	P-loop_NTPase	43..325	CDD:393306	74/306 (24%)
		GBP_C	351..>447	CDD:308475	28/96 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920