Protein Alignment GBP1 and SPAC222.14c

DIOPT Version :9

• Sequence 1: NP_002044.2
• Gene: GBP1 / 2633
• HGNCID: 4182
• Length: 592
• Species: Homo sapiens
• Sequence 2: NP_593153.1
• Gene: SPAC222.14c / 2541926
• PomBaseID: SPAC222.14c
• Length: 762
• Species: Schizosaccharomyces pombe
• Alignment Length: 611
• Identity: 112/611 - (18%)
• Similarity: 206/611 - (33%)
• Gaps: 219/611 - (35%)

Human    40 VVAIVGLYRTGKSYLMNKLAGKKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDV 104
            |||::|...||||.|:|.|.|........|..|..|||||:     .|.....::::|.||....
pombe    41 VVAVLGSQSTGKSTLLNNLFGTSFSVMDASKRQQTTKGIWL-----SKANNSPILVMDVEGTDGR 100

Human   105 EKGDNQNDSWIFALAVLLSSTFVY-----NSIGTINQQAMD----------QLYY---------- 144
            |:|::|:.....||..:.:|..:.     |.:|......|.          ||::
pombe   101 ERGEDQDFERKSALFSISTSEVIIVNMWENQVGLYQGSNMALLKTVLEVNLQLFHNKKERCLLQF 165

Human   145 ------------------VTELTHRIRSKSSPDENENEVEDSADFVSF------------FPDFV 179
                              :|:|.:...|.|.|:..||.|.:....|.|            |.:.|
pombe   166 VIRDFLGNTSMENLADTIMTDLNNIWASLSKPEGFENSVINDFFDVGFTGLPHKILCSDAFSEAV 230

Human   180 WTLRDFSLD---------------LEADGQPLTPDEYLTYSLKLKK--GTSQKDETFNLP----- 222
            .:||:..:|               :.|||          :||..::  .|.:.::..:||
pombe   231 DSLRERFVDNNNSDYIFNVSYHKKIPADG----------FSLYTREIWDTIENNKDLDLPTQQQL 285

Human   223 ---------------------RLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDEELDPEFVQQV 266
                                 .:..::|.|...|  .|.|.   ||..:.:...|..|    :|.
pombe   286 LAQYRCDEIITEVMEPFSTACTILQKEFLPGNLC--KDLPT---KLLNMFETVIEAYD----RQA 341

Human   267 ADFCSYIFSNSKTKTLSG---------GIQVNGPRLESLVLTYVNAISS--GDLPCMENAVLALA 320
            :.:..:|:...|.:.::.         ..|:|....| |:.::.:|.:.  .|.|..|::.:.:.
pombe   342 SRYNVHIYQKKKQELIASVDSHLYVFFQAQLNALHKE-LIKSFFDASNEFPSDTPFKESSSIKIN 405

Human   321 QIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELA 385
            ::.|..          ::.|:.:.||        .:|.|     ::.||            .:|:
pombe   406 ELVNKM----------REEGESLSLP--------HVHWD-----VDPFI------------LKLS 435

Human   386 AQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEE 450
            .:|.:..:..||       ::....|:.:|:..|.||...:       .:..|||
pombe   436 EELTQNSETLCK-------EKLKEKLEELFTGFEFEVSEAV-------EVAFQKL---------- 476

Human   451 PRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRK--- 512
                  :..:..|.|       :..|....|..||.|.|....|..:..:.:.:.:...::.
pombe   477 ------SHNVWDTLL-------NEFLAAQNTTIEKIKNIVPFYVDIDDTKTTEEYIINFKKNSWL 528

Human   513 ----------NEQMMEQKERSYQEHL 528
                      :|.:::|:.|.|.|.|
pombe   529 FFRKKIDSEMSEVLLQQRLRVYFEEL 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBP1	NP_002044.2	GTPase domain (Globular)	1..311		75/379 (20%)
		GBP	18..282	CDD:280433	69/339 (20%)
		GBP_C	284..580	CDD:202427	43/269 (16%)
		GBP_C	290..580	CDD:293879	41/254 (16%)
		coiled coil	549..560	CDD:293879
		coiled coil	569..580	CDD:293879
SPAC222.14c	NP_593153.1	P-loop_NTPase	45..752	CDD:304359	109/607 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910