Protein Alignment GBP1 and mto1

DIOPT Version :9

• Sequence 1: NP_002044.2
• Gene: GBP1 / 2633
• HGNCID: 4182
• Length: 592
• Species: Homo sapiens
• Sequence 2: NP_588284.1
• Gene: mto1 / 2539467
• PomBaseID: SPCC417.07c
• Length: 1115
• Species: Schizosaccharomyces pombe
• Alignment Length: 568
• Identity: 118/568 - (20%)
• Similarity: 206/568 - (36%)
• Gaps: 172/568 - (30%)

Human   141 QLYYVTELTHRIRSKSSPDEN--ENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPDEYLT 203
            ||..:.|..:.:.|:.:|..|  ..::.|.....|...|    |:|....|..:.:...|...||
pombe   190 QLTPIKEERNYLHSQDAPTTNALSKKISDILIPASAMKD----LKDRKNALAKEFEESQPGSSLT 250

Human   204 YSLKLKKGTSQKDETFNLPRLCIRKFFPKKKC-FVFDRPVHRRKLAQLEKLQDEELDPEFVQQVA 267
            ...:.....:.:.|.|.|          |.|| |::|         ||.|..|:|:. :.::|..
pombe   251 LKEQANVIDNLRKEVFGL----------KLKCYFLYD---------QLNKFHDQEVQ-DIMKQNI 295

Human   268 DFCSYIFSNSKT-----KTLSG-----------GIQVNGPRLESLVL---TYVNAISSGDLPCME 313
            |..:......:.     |.:||           .:....|...:|:.   .|..|:|  :|...:
pombe   296 DLKTLTMELQRAVAGYEKKISGLESRIKPDQSFNLSTPSPAPSNLITLQSRYSQALS--ELETTK 358

Human   314 NAVLALAQIENSAAVQKAIAHYEQ----------------------------QMGQKVQLPT--- 347
            .|..||.: |.|.....::..|.:                            |:.:||.:|.
pombe   359 RAFAALRK-EKSKKTNYSVGAYNEDRNVLSNMLDNERREKEALLQELESLRVQLSKKVPMPAKNT 422

Human   348 -----ETLQ---ELLDLHRDSEREAIEVFIRSSFKDVDHLFQ--KELAAQLEKKRDDFCKQNQEA 402
                 ||||   |||.:....:.||:  .:|.  ::.|.|.:  :||...|...:.:...:.:.:
pombe   423 DERVIETLQRSNELLRMDISMQNEAL--LLRK--QENDRLVKQVEELTVALNSGKMNAIVEAESS 483

Human   403 SSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKY----------YEEPRKGIQ- 456
            .::...:::.......|:.::.        .||:.| |||:::.|          :.|....:|
pombe   484 KNELWDSMMVSRMKTQEQSIEL--------TRLYKQ-LQDIEEDYENKLMRMEQQWREDVDQLQE 539

Human   457 -AEEILQTYLKSKESMTDAILQTD-------QTLTEKEKEI-------------------EVERV 494
             .|||.|....:||.::.:..::|       :..||.|:||                   |||::
pombe   540 YVEEITQELQDTKEVLSKSSKESDDYEEVVGKLRTEAEREIEKFEKTIRENEESISLFKEEVEKL 604

Human   495 KAESAQAS-------------AKMLQEMQRKNEQMMEQKERSYQEHLKQL-----------TEKM 535
            ..|..|.|             .|.||.::.:|.:..|.........|:||           .|..
pombe   605 TDEITQLSERYNDKCHEFDELQKRLQTLEEENNKAKEDSTSKTSNLLEQLKMTEAEVDSLRKENE 669

Human   536 ENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKM 583
            ||.:|..|||.|   .:|..:.:.||.|  |.||  :.:::..|:|:|
pombe   670 ENKQVIALKESE---LVKSNDNKLLLNE--QIES--LNDQLSQLKTEM 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBP1	NP_002044.2	GTPase domain (Globular)	1..311		39/191 (20%)
		GBP	18..282	CDD:280433	31/148 (21%)
		GBP_C	284..580	CDD:202427	83/412 (20%)
		GBP_C	290..580	CDD:293879	82/395 (21%)
		coiled coil	549..560	CDD:293879	1/10 (10%)
		coiled coil	569..580	CDD:293879	1/10 (10%)
mto1	NP_588284.1	Cnn_1N	252..319	CDD:285263	18/86 (21%)
		Fib_alpha	511..611	CDD:285864	23/100 (23%)
		Mto2_bdg	1052..1101	CDD:289572

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000