Protein Alignment GBP1 and Gbp2b

DIOPT Version :9

• Sequence 1: NP_002044.2
• Gene: GBP1 / 2633
• HGNCID: 4182
• Length: 592
• Species: Homo sapiens
• Sequence 2: NP_034389.2
• Gene: Gbp2b / 14468
• MGIID: 95666
• Length: 589
• Species: Mus musculus
• Alignment Length: 591
• Identity: 402/591 - (68%)
• Similarity: 497/591 - (84%)
• Gaps: 3/591 - (0%)

Human     1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAGKKKGF 65
            |||||||.||:|||:|:..:|....|||.|||||..|:|||||||.|.|||||||||||||:|||
Mouse     1 MASEIHMKGPVCLIKNSGEQLEVYQEALDILSAIQNPVVVVAIVGFYHTGKSYLMNKLAGKQKGF 65

Human    66 SLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNS 130
            |||||||||||||||||:|||:||.|.|||||||||.|::|||||||.|||||||||||||:|||
Mouse    66 SLGSTVQSHTKGIWMWCMPHPEKPEHTLVLLDTEGLKDMQKGDNQNDCWIFALAVLLSSTFIYNS 130

Human   131 IGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQP 195
            ||||||||||||:||||||..|:||||||  :::|::||:||.|||.|||||||||||||.||:.
Mouse   131 IGTINQQAMDQLHYVTELTDLIKSKSSPD--QSDVDNSANFVGFFPIFVWTLRDFSLDLEFDGES 193

Human   196 LTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDEELDP 260
            :||||||..||.|:|||.:..:.||:|||||||||||:|||:||||..|::|::||.:|:::|:.
Mouse   194 ITPDEYLETSLALRKGTDENTKKFNMPRLCIRKFFPKRKCFIFDRPGDRKQLSKLEWIQEDQLNK 258

Human   261 EFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENS 325
            |||:|||:|.|||||.|..|||||||.||||||:|||.|||:||.||:|||||||||.|||||||
Mouse   259 EFVEQVAEFTSYIFSYSGVKTLSGGITVNGPRLKSLVQTYVSAICSGELPCMENAVLTLAQIENS 323

Human   326 AAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEK 390
            |||||||.:||:||.||:.:|||||||||||||..||||||||:::||||||..||:||.||||.
Mouse   324 AAVQKAITYYEEQMNQKIHMPTETLQELLDLHRTCEREAIEVFMKNSFKDVDQKFQEELGAQLEA 388

Human   391 KRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGI 455
            |||.|.|:|.:.||..||.||:.:|:.||||||.|.:.|||||.||:|:.|:|:|||.:.|.||:
Mouse   389 KRDAFVKKNMDMSSAHCSDLLEGLFAHLEEEVKQGTFYKPGGYYLFLQRKQELEKKYIQTPGKGL 453

Human   456 QAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQK 520
            |||.:|:.|.:|||.:.|.:|:.||:||||||:||:||:|||:|:|:.:.|.|||:|:|.:||||
Mouse   454 QAEVMLRKYFESKEDLADTLLKMDQSLTEKEKQIEMERIKAEAAEAANRALAEMQKKHEMLMEQK 518

Human   521 ERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRR 585
            |:|||||:||||||||.:|.:|:.||:|.::|||||||:|||:|||.||..::.||:.:: .|..
Mouse   519 EQSYQEHMKQLTEKMEQERKELMAEQQRIISLKLQEQERLLKQGFQNESLQLRQEIEKIK-NMPP 582

Human   586 RKACTI 591
            .::|||
Mouse   583 PRSCTI 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBP1	NP_002044.2	GTPase domain (Globular)	1..311		226/309 (73%)
		GBP	18..282	CDD:280433	190/263 (72%)
		GBP_C	284..580	CDD:202427	192/295 (65%)
		GBP_C	290..580	CDD:293879	187/289 (65%)
		coiled coil	549..560	CDD:293879	7/10 (70%)
		coiled coil	569..580	CDD:293879	3/10 (30%)
Gbp2b	NP_034389.2	GBP	19..280	CDD:308078	190/262 (73%)
		GBP_C	282..578	CDD:308475	192/295 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	409	1.000	Domainoid score	I10988
eggNOG	1	0.900	-	-		E1_KOG2037
HGNC	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	842	1.000	Inparanoid score	I7422
Isobase	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55037
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	1	1.000	-	-		FOG0000238
OrthoInspector	1	1.000	-	-		mtm9915
orthoMCL	1	0.900	-	-		OOG6_100467
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X242
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.780