Protein Alignment GBE1 and gbe1b

DIOPT Version :10

• Sequence 1: NP_000149.4
• Gene: GBE1 / 2632
• HGNCID: 4180
• Length: 702
• Species: Homo sapiens
• Sequence 2: XP_068069780.1
• Gene: gbe1b / 559212
• ZFINID: ZDB-GENE-110914-16
• Length: 689
• Species: Danio rerio
• Alignment Length: 676
• Identity: 500/676 - (73%)
• Similarity: 570/676 - (84%)
• Gaps: 0/676 - (0%)

Human    25 VPELARLLEIDPYLKPYAVDFQRRYKQFSQILKNIGENEGGIDKFSRGYESFGVHRCADGGLYCK 89
            ||.|..||::||||||:..||:|||..|.:.|..:.|.|||.|.|:|.||||||.|..|..|..|
Zfish    10 VPHLKSLLQMDPYLKPFEKDFERRYGLFEKQLAFLEEAEGGFDHFTRSYESFGVQRLQDNSLVFK 74

Human    90 EWAPGAEGVFLTGDFNGWNPFSYPYKKLDYGKWELYIPPKQNKSVLVPHGSKLKVVITSKSGEIL 154
            ||||.||.:|||||||||:.||:||.|.::|||||:||||::|:..|.|.||||||:.:.:||.|
Zfish    75 EWAPAAEALFLTGDFNGWDKFSHPYAKKEFGKWELHIPPKEDKTPAVTHNSKLKVVVHTSAGERL 139

Human   155 YRISPWAKYVVREGDNVNYDWIHWDPEHSYEFKHSRPKKPRSLRIYESHVGISSHEGKVASYKHF 219
            ||||||||||.|...:|.|||:||||...|..||.||:||||||||||||||:|.|||:|||.:|
Zfish   140 YRISPWAKYVTRHEKSVIYDWVHWDPPQPYIHKHPRPQKPRSLRIYESHVGIASPEGKIASYSNF 204

Human   220 TCNVLPRIKGLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELQELVDTAHSMGIIVL 284
            |.|||||||.||||.||||||||||||||||||:||||||||||||||||:||:|.|||:|||||
Zfish   205 THNVLPRIKDLGYNSIQLMAIMEHAYYASFGYQVTSFFAASSRYGTPEELKELIDVAHSLGIIVL 269

Human   285 LDVVHSHASKNSADGLNMFDGTDSCYFHSGPRGTHDLWDSRLFAYSSWEILRFLLSNIRWWLEEY 349
            |||||||||||:.||||:|||:|||:|||||||.|.|||||||.|||||:|||||||:|||:|||
Zfish   270 LDVVHSHASKNTEDGLNLFDGSDSCFFHSGPRGEHSLWDSRLFNYSSWEVLRFLLSNLRWWMEEY 334

Human   350 RFDGFRFDGVTSMLYHHHGVGQGFSGDYSEYFGLQVDEDALTYLMLANHLVHTLCPDSITIAEDV 414
            :||||||||||||||||||:|.||||||:||||||||||:|.|||||||::|||..|.|||||||
Zfish   335 KFDGFRFDGVTSMLYHHHGIGSGFSGDYNEYFGLQVDEDSLVYLMLANHILHTLYEDCITIAEDV 399

Human   415 SGMPALCSPISQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGDIVYTLTNRRYLEKCIAYAES 479
            ||||.||.|:.|||.||||||||||||||||:||||||||||||:||:|:|||||.|||||||||
Zfish   400 SGMPTLCCPVQQGGLGFDYRLAMAIPDKWIQILKEFKDEDWNMGNIVFTMTNRRYGEKCIAYAES 464

Human   480 HDQALVGDKSLAFWLMDAEMYTNMSVLTPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFG 544
            |||||||||:|||||||.||||:||.|.|...:|||||||||||||:||.|||||||||||||||
Zfish   465 HDQALVGDKTLAFWLMDKEMYTSMSALIPMNSIIDRGIQLHKMIRLLTHSLGGEGYLNFMGNEFG 529

Human   545 HPEWLDFPRKGNNESYHYARRQFHLTDDDLLRYKFLNNFDRDMNRLEERYGWLAAPQAYVSEKHE 609
            |||||||||.||||||||||||::|.|.|.|||:.|..|||||||.|:.|||||||.||||.|||
Zfish   530 HPEWLDFPRIGNNESYHYARRQYNLVDMDHLRYRQLYAFDRDMNRTEDNYGWLAAPPAYVSVKHE 594

Human   610 GNKIIAFERAGLLFIFNFHPSKSYTDYRVGTALPGKFKIVLDSDAAEYGGHQRLDHSTDFFSEAF 674
            |:|:|.||||.|:|||||||..||:||||.....||:||.||||..:||||.||||:|:||:||.
Zfish   595 GDKVIVFERANLIFIFNFHPFNSYSDYRVAVGPAGKYKIKLDSDEIQYGGHGRLDHNTEFFTEAM 659

Human   675 EHNGRPYSLLVYIPSRVALILQNVDL 700
            ..|.||.|::||||.|.|::|.|.::
Zfish   660 GLNNRPNSMMVYIPCRTAIVLANEEI 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBE1	NP_000149.4	PLN02447	2..699	CDD:215246	500/673 (74%)
gbe1b	XP_068069780.1	PLN02447	16..686	CDD:215246	497/670 (74%)