Protein Alignment GBE1 and T04A8.7

DIOPT Version :10

• Sequence 1: NP_000149.4
• Gene: GBE1 / 2632
• HGNCID: 4180
• Length: 702
• Species: Homo sapiens
• Sequence 2: NP_497961.1
• Gene: T04A8.7 / 3565201
• WormBaseID: WBGene00011409
• Length: 681
• Species: Caenorhabditis elegans
• Alignment Length: 676
• Identity: 381/676 - (56%)
• Similarity: 490/676 - (72%)
• Gaps: 4/676 - (0%)

Human    26 PELARLLEIDPYLKPYAVDFQRRYKQFSQILKNIGENEGGIDKFSRGYESFGVHRCADGGLYCKE 90
            |::..||:|||||..:..:..|||..|....:.| |..||:::|:..|:.||::...|..:...|
 Worm     7 PKIDELLKIDPYLHDFQDEISRRYGVFLDYQRRI-EECGGMEEFTSSYKQFGLNVQPDNSVKGLE 70

Human    91 WAPGAEGVFLTGDFNGWNPFSYPYKKLDYGKWELYIPPKQNKSVLVPHGSKLKVVITSKSGEILY 155
            |||.||.:.|.||||.|:..:..|||.::|||.:.:|.|::.|..:||.|.:|:.: |:.|...:
 Worm    71 WAPAAEKLALIGDFNNWDQNANVYKKEEHGKWSITVPAKEDGSCPIPHNSVIKIAV-SRHGATHF 134

Human   156 RISPWAKYVV--REGDNVNYDWIHWDPEHSYEFKHSRPKKPRSLRIYESHVGISSHEGKVASYKH 218
            ::||||.:|.  ...:.|.|....|:|...|:.|.:||.:|.||||||:||||||.|||:.:|:.
 Worm   135 KLSPWATFVTCPNPKETVIYHQNFWNPPEKYQLKEARPARPASLRIYEAHVGISSSEGKINTYRE 199

Human   219 FTCNVLPRIKGLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELQELVDTAHSMGIIV 283
            |..:|||||:..|||.|||||:|||.||||||||:::|||.|||.||||:|:.|||.|||:||.:
 Worm   200 FADDVLPRIQKQGYNAIQLMAVMEHVYYASFGYQVSNFFAVSSRCGTPEDLKYLVDKAHSLGIFM 264

Human   284 LLDVVHSHASKNSADGLNMFDGTDSCYFHSGPRGTHDLWDSRLFAYSSWEILRFLLSNIRWWLEE 348
            ||||||||||||..||||.:||::..|||...||.|:|||||||.|:..|.|||||||:|||:||
 Worm   265 LLDVVHSHASKNVEDGLNQWDGSNGGYFHDNARGYHNLWDSRLFDYTQTETLRFLLSNVRWWVEE 329

Human   349 YRFDGFRFDGVTSMLYHHHGVGQGFSGDYSEYFGLQVDEDALTYLMLANHLVHTLCPDSITIAED 413
            |.|||||||||:||:||.||:...|.|.|..||||..|.|:|.||||||..:|...|..|||||:
 Worm   330 YGFDGFRFDGVSSMIYHSHGMNDDFCGGYPMYFGLNADTDSLVYLMLANDFLHKKYPFMITIAEE 394

Human   414 VSGMPALCSPISQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGDIVYTLTNRRYLEKCIAYAE 478
            |||||.:|.|:.:||.|||||||||:||.||::||...||||.:.|||:.|.||||.||.:||||
 Worm   395 VSGMPGICRPVEEGGQGFDYRLAMALPDMWIKILKHTSDEDWKIDDIVFNLENRRYAEKHVAYAE 459

Human   479 SHDQALVGDKSLAFWLMDAEMYTNMSVLTPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEF 543
            ||||||||||::||||||.|||..||..:|.||:||||:.|||:|||||.|||||.:|||:||||
 Worm   460 SHDQALVGDKTIAFWLMDKEMYDFMSTDSPLTPIIDRGLSLHKLIRLITIGLGGEAWLNFIGNEF 524

Human   544 GHPEWLDFPRKGNNESYHYARRQFHLTDDDLLRYKFLNNFDRDMNRLEERYGWLAAPQAYVSEKH 608
            ||||||||||.||.||:|||||||:|.|.:.||||||||:||:|..||||.|:|....||.|.||
 Worm   525 GHPEWLDFPRVGNGESFHYARRQFNLVDAEYLRYKFLNNWDREMMLLEERTGFLHKGYAYTSWKH 589

Human   609 EGNKIIAFERAGLLFIFNFHPSKSYTDYRVGTALPGKFKIVLDSDAAEYGGHQRLDHSTDFFSEA 673
            :|:|.|.|||.||:|:.|.||:||:.||.:|...||:::|.|:||.:::|||.|:|:|..|.:..
 Worm   590 DGDKTIVFERGGLVFVINLHPTKSFADYSIGVNTPGRYRIALNSDESKFGGHNRIDNSIKFHTTD 654

Human   674 FEHNGRPYSLLVYIPSRVALILQNVD 699
            ..:.||.:.|.|||..|.|::|:..|
 Worm   655 DGYAGRRHRLQVYITCRTAIVLEKED 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBE1	NP_000149.4	PLN02447	2..699	CDD:215246	380/674 (56%)
T04A8.7	NP_497961.1	PLN02447	1..681	CDD:215246	381/676 (56%)