DRSC/TRiP Functional Genomics Resources

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Protein Alignment GBE1 and mde5

DIOPT Version :10

Sequence 1:NP_000149.4 Gene:GBE1 / 2632 HGNCID:4180 Length:702 Species:Homo sapiens
Sequence 2:NP_001343001.1 Gene:mde5 / 3361499 PomBaseID:SPAC25H1.09 Length:513 Species:Schizosaccharomyces pombe


Alignment Length:260 Identity:56/260 - (21%)
Similarity:104/260 - (40%) Gaps:68/260 - (26%)


- Green bases have known domain annotations that are detailed below.


Human   224 LPRIKGLGYNCIQLMAIMEH---------AYYASFGYQITSFFAASSRYGTPEELQELVDTAHSM 279
            |..|:|:|:..|.:..|:::         ||:   ||.....:..:..:||.::|.:|.|..|..
pombe    71 LDYIQGMGFTAIWISPIIKNIEGRTKYGEAYH---GYWPQDLYTLNPHFGTEQDLIDLADALHDR 132

Human   280 GIIVLLDVVHSHASKNSADGLNMFDG-----TDSCYFH-------SGPRGTHDLW----DSRL-- 326
            |:.:::|.|.:|  ..|:|..|:..|     ..|.::|       ..|......|    |..|  
pombe   133 GMYLMVDTVVNH--MGSSDPRNIDYGIYRPFNQSSHYHPMCPIEQDKPLSLEQCWIGTEDMTLPD 195

Human   327 FAYSSWEILRFLLSNIRWWLEEYRFDGFRFDGVTSM-------LYHHHGV---GQGFSG------ 375
            ....:.:|:..|.:.|...:::::.||.|.|....:       .....||   |:.::|      
pombe   196 IDTENPQIIETLYNFIHDQVKQFKIDGLRVDATKHVRRTFWPGFCESAGVYCQGEEWTGQADLFC 260

Human   376 DYSEY------FGLQ---------VDEDALTYLMLANHLVHTLCPDSITI-----AEDVSGMPAL 420
            ::.||      |.:|         :::.||....:|.:||...|.||..:     ::|...:.||
pombe   261 EWQEYMDGLHNFPVQGVAAESVIPLNDRALRKTAIAMNLVAHHCKDSTLLGLFLESQDAPRLAAL 325

Human   421  420
            pombe   326  325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GBE1NP_000149.4 PLN02447 2..699 CDD:215246 56/260 (22%)
mde5NP_001343001.1 AmyAc_euk_AmyA 26..396 CDD:200458 56/260 (22%)
A_amylase_dom_C 410..488 CDD:370390
Blue background indicates that the domain is not in the aligned region.

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