DRSC/TRiP Functional Genomics Resources

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Protein Alignment GBE1 and aah2

DIOPT Version :10

Sequence 1:NP_000149.4 Gene:GBE1 / 2632 HGNCID:4180 Length:702 Species:Homo sapiens
Sequence 2:NP_594551.1 Gene:aah2 / 2541501 PomBaseID:SPAC23D3.14C Length:581 Species:Schizosaccharomyces pombe


Alignment Length:416 Identity:91/416 - (21%)
Similarity:148/416 - (35%) Gaps:124/416 - (29%)


- Green bases have known domain annotations that are detailed below.


Human   222 NVLPRIKGLGYNCIQLMAIMEH---------AYYASFGYQITSFFAASSRYGTPEELQELVDTAH 277
            |.|..|:|:|::.|.:..|.|:         :|:   ||..|:.:..:..:||.||..||:...|
pombe    73 NHLDYIQGMGFDAIWISPIFENVEGNDIDGSSYH---GYWTTNLYELNHHFGTKEEFMELIQELH 134

Human   278 SMGIIVLLDV-VHSHASKNSADGLN---MFDGTDSCYFH---------SGPRGTHDLW--DSRLF 327
            ...|.:|||| ::|.|.....:.::   :....|:.:||         :......:.|  |..|.
pombe   135 KRDIWILLDVAINSMAINGPLEQMSFEKVIPFNDASFFHPHCWVDYESNDIESVQNCWLGDENLL 199

Human   328 AYSSWEILRFLLSNIRWWL----EEYRFDGFRFDGVTSMLYHHHGVGQGFSGDYSEYFGLQVDED 388
            ..........:||.:..|:    :||..||.|||.:     .|..:          .|.|::.:.
pombe   200 LADVDTENEVVLSVLEKWIKNVVQEYDIDGIRFDAI-----KHAPI----------EFWLRMSKA 249

Human   389 ALTYLMLANHLVHTLCPDSITIAEDVSGMPA-LCSPISQGGGGFDYRLAMAIPDKWIQLLKEFKD 452
            |                |..||.|..:|.|| .|...:.|...|     :..|..|         
pombe   250 A----------------DIFTIGEYFTGSPAEACDYQNSGLDSF-----LNFPLYW--------- 284

Human   453 EDWNMGDIVYTLTNRRYLEKCIAYAESHDQALVGDKSLAFWLMDAEMYTNMSVLTPFTPVIDRGI 517
                  .|.:...|...  :|.|.|.:.:|.             .|...:::||..|....|...
pombe   285 ------PITWAFNNTGL--QCEALAIAINQI-------------NEECNDINVLGTFIGNHDLPR 328

Human   518 QLH------KMIRLITHGLGGEGY-LNFMGNEFGHPEWLDFPRKGNNESYH--YARRQFHLTDDD 573
            ..|      :::..||..:..:|. :.:.|.|            .|..|||  :.|....|::.|
pombe   329 ISHNNTDQARIMNAITFVMMWDGIPIIYYGTE------------QNFNSYHDPFNREALWLSNFD 381

Human   574 L--LRYK---FLNNFDRDMNRLEERY 594
            :  :.||   .||.|.:.:.|.||.|
pombe   382 MENVYYKLIGILNRFRKSVQRQEENY 407

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GBE1NP_000149.4 PLN02447 2..699 CDD:215246 91/416 (22%)
aah2NP_594551.1 AmyAc_euk_AmyA 26..403 CDD:200458 87/410 (21%)
A_amylase_dom_C 420..497 CDD:370390
Blue background indicates that the domain is not in the aligned region.

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