Protein Alignment GBE1 and aah1

DIOPT Version :10

• Sequence 1: NP_000149.4
• Gene: GBE1 / 2632
• HGNCID: 4180
• Length: 702
• Species: Homo sapiens
• Sequence 2: NP_587687.1
• Gene: aah1 / 2538825
• PomBaseID: SPCC757.12
• Length: 625
• Species: Schizosaccharomyces pombe
• Alignment Length: 344
• Identity: 77/344 - (22%)
• Similarity: 126/344 - (36%)
• Gaps: 95/344 - (27%)

Human   224 LPRIKGLGYNCIQLMAI---MEHAY----YASFGYQITSFFAASSRYGTPEELQELVDTAHSMGI 281
            |..|:|:|:|.|.:..:   :|.:|    .|..||..|.|...:..:|:.::|.:|:...|:..:
pombe    70 LDYIQGMGFNAIWISPVEKNLEGSYGSDGEAYHGYWNTDFTQLNEHFGSEDDLIDLITDMHNRDM 134

Human   282 IVLLD-VVHSHASKNSADGL---NMFDGTDSCYFH---------SGPRGTHDLW---DSRLFA-- 328
            .::.| :.:|.|.....|.:   |:....||.|||         :......|.|   |:.:.|
pombe   135 WIMFDALANSMAIPGPTDNISYSNLVPFNDSSYFHPYCWIDYGSNNNTDIEDCWTGDDNVILADL 199

Human   329 -YSSWEILRFLLSNIRWWLEEYRFDGFRFDGVTSMLYHHHGVGQGFSGDYSEYFGLQVDEDALTY 392
             ..|..:..:|..:|...:|.|:.||.|.|.|..|       ...|..:|:...|:....:..:|
pombe   200 DIESTNVADYLHEHIHDMVERYQIDGIRIDAVKQM-------NPEFFPNYTSAAGVFAIGEMFSY 257

Human   393 -----LMLANHLVHTLCPDSITIAEDVSGMPALCSPISQG--------GGGFDY------RLAMA 438
                 ..:.|:|      ||||           ..||.||        |..|:|      :...|
pombe   258 DPNVSCSVRNYL------DSIT-----------SYPIRQGIEFAFNYTGAAFEYLQEIDTQFQQA 305

Human   439 IPDKWIQLLKEF-------------KDEDWNMGDIVYTLTNRRYLEKCIAYAESHDQALVG---- 486
            ...:.:.::..|             .|...::|.||:.|.:...  ..|.|.|  :|.|.|
pombe   306 CEGQDMSVIGNFLENHDLPRYTSITNDTSQDIGAIVFLLLHTGI--PIIYYGE--EQRLPGGSDT 366

Human   487 -DKSLAFWL----MDAEMY 500
             :...|.|.    .||..|
pombe   367 PENRAALWNYGYDTDANYY 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBE1	NP_000149.4	PLN02447	2..699	CDD:215246	77/344 (22%)
aah1	NP_587687.1	AmyAc_euk_AmyA	23..401	CDD:200458	77/344 (22%)
		A_amylase_dom_C	422..490	CDD:370390