Protein Alignment GBE1 and gbe1

DIOPT Version :10

• Sequence 1: NP_000149.4
• Gene: GBE1 / 2632
• HGNCID: 4180
• Length: 702
• Species: Homo sapiens
• Sequence 2: XP_012813413.2
• Gene: gbe1 / 100494084
• XenbaseID: XB-GENE-980510
• Length: 686
• Species: Xenopus tropicalis
• Alignment Length: 676
• Identity: 525/676 - (77%)
• Similarity: 601/676 - (88%)
• Gaps: 0/676 - (0%)

Human    24 DVPELARLLEIDPYLKPYAVDFQRRYKQFSQILKNIGENEGGIDKFSRGYESFGVHRCADGGLYC 88
            :||||..||..|.|||||..||:|||..|.::||:|..||||::||||.|:|||:|...:||:.|
 Frog     9 EVPELKVLLGQDSYLKPYEKDFRRRYGLFCRLLKSIEGNEGGLEKFSRSYQSFGIHLLENGGICC 73

Human    89 KEWAPGAEGVFLTGDFNGWNPFSYPYKKLDYGKWELYIPPKQNKSVLVPHGSKLKVVITSKSGEI 153
            ||||||||.||||||||||||||:||||:|||||||:|||:::||.::||||||||||||||||.
 Frog    74 KEWAPGAEAVFLTGDFNGWNPFSHPYKKMDYGKWELHIPPREDKSAIIPHGSKLKVVITSKSGET 138

Human   154 LYRISPWAKYVVREGDNVNYDWIHWDPEHSYEFKHSRPKKPRSLRIYESHVGISSHEGKVASYKH 218
            |||||||||||:||.:...||||||:|...|:.||:.|||.:|:|||||||||:|.||::||||:
 Frog   139 LYRISPWAKYVIREDNKAVYDWIHWEPPQPYKRKHASPKKLKSVRIYESHVGIASSEGRIASYKN 203

Human   219 FTCNVLPRIKGLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELQELVDTAHSMGIIV 283
            ||.||||:||.|||||||:|||||||||||||||:|||||||||:|||:||:||:|.||||||.|
 Frog   204 FTYNVLPKIKDLGYNCIQMMAIMEHAYYASFGYQVTSFFAASSRFGTPDELKELIDVAHSMGIQV 268

Human   284 LLDVVHSHASKNSADGLNMFDGTDSCYFHSGPRGTHDLWDSRLFAYSSWEILRFLLSNIRWWLEE 348
            |||||||||||||.||||.||||::|:||.|.||.|||||||||.||:||:|||||||:||||||
 Frog   269 LLDVVHSHASKNSEDGLNKFDGTNACFFHDGARGNHDLWDSRLFDYSNWEVLRFLLSNLRWWLEE 333

Human   349 YRFDGFRFDGVTSMLYHHHGVGQGFSGDYSEYFGLQVDEDALTYLMLANHLVHTLCPDSITIAED 413
            |.||||||||||||||||||:|.||||||:||||||||||:|.|||||||:.|||.|||||||||
 Frog   334 YGFDGFRFDGVTSMLYHHHGIGCGFSGDYNEYFGLQVDEDSLVYLMLANHMTHTLYPDSITIAED 398

Human   414 VSGMPALCSPISQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGDIVYTLTNRRYLEKCIAYAE 478
            ||||||||.||||||.|||||||||:||||||:|||.|||:|:||:||:|||||||.||||||||
 Frog   399 VSGMPALCCPISQGGTGFDYRLAMAVPDKWIQILKELKDEEWDMGNIVHTLTNRRYNEKCIAYAE 463

Human   479 SHDQALVGDKSLAFWLMDAEMYTNMSVLTPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEF 543
            ||||||||||:||||||||||||||||::|.|||||||||||||:|||||||||||||||:||||
 Frog   464 SHDQALVGDKTLAFWLMDAEMYTNMSVMSPLTPVIDRGIQLHKMLRLITHGLGGEGYLNFIGNEF 528

Human   544 GHPEWLDFPRKGNNESYHYARRQFHLTDDDLLRYKFLNNFDRDMNRLEERYGWLAAPQAYVSEKH 608
            |||||||||||||.||||||||||||.||:.|||:||..||||||:|||::|||||||||:|.||
 Frog   529 GHPEWLDFPRKGNGESYHYARRQFHLIDDNQLRYRFLYAFDRDMNKLEEKFGWLAAPQAYISAKH 593

Human   609 EGNKIIAFERAGLLFIFNFHPSKSYTDYRVGTALPGKFKIVLDSDAAEYGGHQRLDHSTDFFSEA 673
            |.:||||||||.|||||||||.||:|.||||....|||.|.||:||:|||||:|::|.|:||:|.
 Frog   594 EDDKIIAFERANLLFIFNFHPYKSFTGYRVGVNTHGKFMIALDTDASEYGGHERINHKTEFFTEH 658

Human   674 FEHNGRPYSLLVYIPSRVALILQNVD 699
            ..:||..:|||||||.||||:|.|||
 Frog   659 SPYNGCSHSLLVYIPCRVALVLSNVD 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GBE1	NP_000149.4	PLN02447	2..699	CDD:215246	523/674 (78%)
gbe1	XP_012813413.2	PLN02447	20..684	CDD:215246	517/663 (78%)