Protein Alignment HIBCH and HIPP1

DIOPT Version :10

• Sequence 1: NP_055177.2
• Gene: HIBCH / 26275
• HGNCID: 4908
• Length: 386
• Species: Homo sapiens
• Sequence 2: NP_649261.1
• Gene: HIPP1 / 40302
• FlyBaseID: FBgn0037027
• Length: 926
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 68/314 - (21%)
• Similarity: 114/314 - (36%)
• Gaps: 79/314 - (25%)

Human    29 SKHT--------DAAEEVLLEK--KGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPE--T 81
            |.||        :.:|.|.|.|  |....||...|..|.:..:..::.|:...|....:..|  |
  Fly   654 SSHTLANDMKANNGSELVCLHKVNKVAHLVIHTERGNFGHTYSKQLLEQLNDTLSSVARKGEFNT 718

Human    82 FLIIIKGAGGKAFCAGGDIRVISEA--EKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITM 144
            .|:.::   |..||.|.|.:.:.:.  ||.|...:.:....:..| ..:.:..||.||.|.|..:
  Fly   719 VLLTVE---GPQFCQGIDCQELIQGSLEKRKDSASQLAVALKCYL-RTLATFPKPLVAGIVGSQI 779

Human   145 GGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFL----PRLQGKLGYFLALTGFRLKGR 205
            ..||.......:.||::.|.|......:|..|:   ||.|    .|:..::...|.|.|.||
  Fly   780 NLGVMQLPFADYVVASDDCSFETNYAKLGQLPE---GYALWHGHQRVSSEVHSRLFLMGERL--- 838

Human   206 DVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINS 270
                  .||..::|                                     .||:     |||
  Fly   839 ------FATELLES-------------------------------------NSFV-----DKI-- 853

Human   271 CFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQE 324
            |.:.|..|..:...:|..:|.| |..:.:.|::.:::.:|....::...|.:.|
  Fly   854 CKARNVNEMALAKAKQISTSSA-EMYRTLKKLNHSAVNVTKFPRLDEELKVIGE 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIBCH	NP_055177.2	ECH_2	46..376	CDD:465024	60/287 (21%)
HIPP1	NP_649261.1	PTZ00449	<148..580	CDD:185628
		crotonase-like	673..870	CDD:119339	55/256 (21%)