Protein Alignment TSPAN17 and Tsp86D

DIOPT Version :9

• Sequence 1: NP_001353420.1
• Gene: TSPAN17 / 26262
• HGNCID: 13594
• Length: 355
• Species: Homo sapiens
• Sequence 2: NP_001262468.1
• Gene: Tsp86D / 41310
• FlyBaseID: FBgn0037848
• Length: 316
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 117/307 - (38%)
• Similarity: 166/307 - (54%)
• Gaps: 54/307 - (17%)

Human     7 HFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG---LDPVW--- 65
            ||.  .|..|.||.:|..|.:||:.|.|.||||::|:.:|        |.|..|   ||.::
  Fly    23 HFS--YVSSCVKYMIFLLNFLFWLFGGLLLAIGVYAFMDK--------LMDGNGWLRLDTIYDVI 77

Human    66 -----LFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQL 125
                 :.::.|.::..:.||||:|||||||:|||.:|:.|.|.|.||::..|:.|||..::...|
  Fly    78 FNISLVMIIAGVIVFTVSFAGCLGALRENTWLLKLYSMCLLLFFILEMSLAIICFVFPQYMNSFL 142

Human   126 NL-FINNNVKAYRDDIDLQNLIDFAQEYWSCCGA--RGPNDWNLNIYFNCTDLNPSRERCGVPFS 187
            .. |.:..:.:||||.||||.|||||:.::|||.  .|..||:.|.||||:  :||.||||||:|
  Fly   143 EYQFTDKIIHSYRDDSDLQNFIDFAQQEFNCCGLSNAGYQDWSKNEYFNCS--SPSVERCGVPYS 205

Human   188 CCVR--DPAEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQV 250
            ||:.  |.:..::|..|||.|:::........|.|.||:.....|::.||.|:|||.:||||
  Fly   206 CCINATDISSGLVNIMCGYGVQVRSVAAASKRIWTSGCIEIVRVWVERNLYVIAGVALGIAL--- 267

Human   251 PLWPHVPLPLPGPPSLSPHLSSVLQIFGICLAQNLVSDIKAVKANWS 297
                                   ||:|.|.||:.|...|...|:.||
  Fly   268 -----------------------LQLFVIYLAKTLEGQIDLQKSRWS 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSPAN17	NP_001353420.1	TM4SF9_like_LEL	115..235	CDD:239412	51/124 (41%)
Tsp86D	NP_001262468.1	Tetraspannin	51..283	CDD:278750	100/267 (37%)
		penumbra_like_LEL	132..255	CDD:239411	51/124 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48585
OrthoDB	1	1.010	-	-		D574036at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X349
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.890