Protein Alignment GARS1 and Gars1

DIOPT Version :10

• Sequence 1: NP_002038.2
• Gene: GARS1 / 2617
• HGNCID: 4162
• Length: 739
• Species: Homo sapiens
• Sequence 2: NP_001258068.1
• Gene: Gars1 / 297113
• RGDID: 1307856
• Length: 728
• Species: Rattus norvegicus
• Alignment Length: 739
• Identity: 676/739 - (91%)
• Similarity: 705/739 - (95%)
• Gaps: 11/739 - (1%)

Human     1 MPSPRPVLLRGARAALLLLLPPRLLARPSLLLRRSLSAASCPPISLPAAASRSSMDGAGAEEVLA 65
            ||...|.|||..||| |||..||::|.|:  .:|.|||.:.|      |||.||||  .|||:||
  Rat     1 MPCLLPTLLRATRAA-LLLQSPRVVAAPA--SQRLLSAPAQP------AASPSSMD--SAEELLA 54

Human    66 PLRLAVRQQGDLVRKLKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKR 130
            |||||||||||.|||||||||||||||:|||||||||||||||||||||||||||||||||||||
  Rat    55 PLRLAVRQQGDFVRKLKEDKAPQVDVDRAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKR 119

Human   131 RFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHV 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   120 RFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHV 184

Human   196 DKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVLAQLDNYGQQELADLFVN 260
            |||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||
  Rat   185 DKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSAEKKSEMESVLAQLDNYGQQELADLFVN 249

Human   261 YNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQ 325
            ||||||.|||||||||.|||||:||||||||||||||||||||||||||||||||||||||||||
  Rat   250 YNVKSPTTGNDLSPPVPFNLMFQTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQ 314

Human   326 IGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKM 390
            ||||||||||||||||||||||||||||||||:|||||||.:||||:||||||||||:|||||||
  Rat   315 IGNSFRNEISPRSGLIRVREFTMAEIEHFVDPTEKDHPKFPSVADLYLYLYSAKAQVTGQSARKM 379

Human   391 RLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGW 455
            |||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   380 RLGDAVEQGVINNSVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGW 444

Human   456 IEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLA 520
            ||||||||||||||||||||||||||||||||||||||||||||:|||:|||||||||||:|||.
  Rat   445 IEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPNKGAVGKAYKKDAKLVLEYLG 509

Human   521 ICDECYITEMEMLLNEKGEFTIETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIM 585
            .||||||||||:||:||||||||||||||||||||::||||||||:||||||:||||||||||||
  Rat   510 ACDECYITEMELLLSEKGEFTIETEGKTFQLTKDMVSVKRFQKTLHVEEVVPSVIEPSFGLGRIM 574

Human   586 YTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDS 650
            ||:.|||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||
  Rat   575 YTILEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRNGVSHKVDDS 639

Human   651 SGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNIT 715
            |||||||||||||||||||:||||||||||||||||||||||||||||:|||||:|:||||||||
  Rat   640 SGSIGRRYARTDEIGVAFGITIDFDTVNKTPHTATLRDRDSMRQIRAEVSELPSVVRDLANGNIT 704

Human   716 WADVEARYPLFEGQETGKKETIEE 739
            |||||||||||||||||||||:||
  Rat   705 WADVEARYPLFEGQETGKKETVEE 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GARS1	NP_002038.2	PLN02734	61..724	CDD:178335	631/662 (95%)
Gars1	NP_001258068.1	PLN02734	45..713	CDD:178335	635/669 (95%)