DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rpb7 and POLR2G

DIOPT Version :9

Sequence 1:	NP_731983.1	Gene:	Rpb7 / 261631	FlyBaseID:	FBgn0051155	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_002687.1	Gene:	POLR2G / 5436	HGNCID:	9194	Length:	172	Species:	Homo sapiens

Alignment Length:	172	Identity:	140/172 - (81%)
Similarity:	157/172 - (91%)	Gaps:	0/172 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYHISLEQEILLHPRYFGPQLLETVKQKLYSEVEGTCTGKYGFVIAVTTIDQIGSGVIQPGQGF 65
            ||||||||.|||||||||||.||.||||||::||||||||||||||||||||.||:||||||:||
Human     1 MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGAGVIQPGRGF 65

  Fly    66 VVYPVKYKAIVFRPFKGEVLDAVVKQINKVGMFAEIGPLSCFISHHSIPADMQFCPNGNPPCYKS 130
            |:|||||||||||||||||:||||.|:||||:|.||||:|||||.||||::|:|.||.||||||:
Human    66 VLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKT 130

  Fly   131 KDEDVVISGEDKIRLKIVGTRVDATGIFAIGTLMDDYLGLVS 172
            .|||:||..:|:|||||||||||...|||||:||||||||||
Human   131 MDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpb7	NP_731983.1	PTZ00162	1..173	CDD:240298	140/172 (81%)
POLR2G	NP_002687.1	PTZ00162	1..169	CDD:240298	135/167 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159080
Domainoid	1	1.000	129	1.000	Domainoid score	I5265
eggNOG	1	0.900	-	-		E1_COG1095
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2019
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2737
Isobase	1	0.950	-	0	Normalized mean entropy	S329
OMA	1	1.010	-	-		QHG54448
OrthoDB	1	1.010	-	-		D1140388at2759
OrthoFinder	1	1.000	-	-		FOG0004872
OrthoInspector	1	1.000	-	-		oto91768
orthoMCL	1	0.900	-	-		OOG6_102167
Panther	1	1.100	-	-	LDO	PTHR12709
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1187
SonicParanoid	1	1.000	-	-		X3436
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.840