Protein Alignment Unc-115a and Ablim1

DIOPT Version :10

• Sequence 1: NP_001163573.1
• Gene: Unc-115a / 261629
• FlyBaseID: FBgn0051352
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001382083.1
• Gene: Ablim1 / 307989
• RGDID: 1565768
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 1016
• Identity: 309/1016 - (30%)
• Similarity: 402/1016 - (39%)
• Gaps: 372/1016 - (36%)

  Fly     7 ISIPKHPQTDKTRP--------IYPSTLG-TELRTELGKT----------GQGKQKIYCAKCTKK 52
            :|:|:.|...:.|.        :|.|..| .|||.....:          ...|..|:|.||.:.
  Rat    42 LSVPETPHPARHRHGTVTYLFYLYSSNRGPPELRFSSCDSSVAHPQDPHHSSEKPVIHCHKCGEP 106

  Fly    53 CSGEVLRVADNHFHKACFQCCQCKKSLATGGFFTKDNAYYCIPDYQRLYGTKCANCQQYVEGEVV 117
            |.||||||...|||..||.|..|...||.||||.|:..|.|..||||:|||:|..|.::||||||
  Rat   107 CKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVV 171

  Fly   118 STMGKTYHQKCFTCSKCKQPFKSGSKVTNTGKEVLCEQCVTGAPVSPSRQATGGGVSSPAPPAES 182
            :.:|||||..||.|:.||:||..|.:||..|::.||:.|.                   .|.:.|
  Rat   172 TALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCA-------------------QPMSSS 217

  Fly   183 PTRATAHQQHGSVISHKAHLKEDYDPNDCAGCGELLKEGQALVALDRQWHVSCFRCKACQAVLNG 247
            |..||.                   .::|||||..:|.||||:|||:|||:.||:||:|..||.|
  Rat   218 PKEATC-------------------SSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTG 263

  Fly   248 EYMGKDAVPYCEKCYQKGFGVKCAYCSRFISGKVLQAGDNHHFHPTCARCTKCGDPFGDGEEMYL 312
            ||:.||..|||||.||..|||||..|.:||:||||:|||. |:||:||||::|...|.:||||||
  Rat   264 EYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGDK-HYHPSCARCSRCNQMFTEGEEMYL 327

  Fly   313 QGSAIWHPRC--------------------------------GPGP------------------- 326
            |||.:|||.|                                |..|
  Rat   328 QGSTVWHPDCKQSTKTEEKLRPPNIPRSSSDFFYPKSLIRRTGRSPALQHLSPPCLVNSNQNPRQ 392

  Fly   327 ----SESGIILNGGGGTSSVVGGASNGNF--TDTEC----------------------------- 356
                |...|....|   ||:.|...:..:  .|.|.
  Rat   393 PTRTSSESIYSRPG---SSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPF 454

  Fly   357 ------DRMSSSALSEM-YIRSRTPSFNGSLYSSSRKHYRTVSPGLILREYGRPNAEDISRIYTY 414
                  |:....:|.|. ...|.|||..|......|..:|:.|.|.|
  Rat   455 YTSGYEDKQDRQSLGESPRTLSPTPSAEGFQDGRDRMIHRSTSQGSI------------------ 501

  Fly   415 SYLTDAPHYLRKPIDPYDKTPLSP-HFHRP---------------SSYATTASNAGSVAGSRPPS 463
                ::|.|.|....|  .|..|| |||||               ||:::|.|:    ....||.
  Rat   502 ----NSPVYSRHSYTP--TTSRSPQHFHRPELLSPGVHRWSPLRTSSFSSTHSD----TRPNPPF 556

  Fly   464 R-----------PHSRTRSAMKVLVDAIRSETP----RPK-----SPGMN--------------- 493
            |           |.|...|.:....|: |..||    .||     ..|:|
  Rat   557 RHHFLPHVKGNEPSSGRNSPLPYRPDS-RPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALA 620

  Fly   494 -----NEEPIELSHYPAAKKPPPGEQPKIERDDFPAPPYPY---TDPERRRRYSDTYKGVPASDD 550
                 :|:.|:.|.:|||:.|.|.|.||||.|.:|.||...   |||.||          .:..:
  Rat   621 AQNKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAIGTDPRRR----------SSGRE 675

  Fly   551 EDENVENGKPNGKVKNGEEQQRLQREAEQLEKLNSGIGSAIAKDLKEHAKYRKWKQNNLDPRNAS 615
            |||.             |..:|.|.:.|||.|||||:|..|.|:..|       |:|.
  Rat   676 EDEE-------------ELLRRRQLQEEQLMKLNSGLGQLILKEEME-------KENR------- 713

  Fly   616 RTPSASKEPLYKLRYESPIGASPSRNLDHQKPFYEDEMFDRSTSYRGSLGKSLGNAPSYNAIHSY 680
                 .:..|...||:||:                               .|..:||      |.
  Rat   714 -----ERASLLASRYDSPL-------------------------------HSASHAP------SS 736

  Fly   681 RSPPKPGYGFKTTTLPYIRNGFSSDF----SYGGLGDKTHSTDLSCGKSEASVDSITEGDRRALM 741
            ::...||||......|     .|:||    |||         |:|.|..          |.:.|.
  Rat   737 KTSSLPGYGKSGLHRP-----VSTDFAQYNSYG---------DVSGGVR----------DYQTLP 777

  Fly   742 GGDLPASSTYSGALSYHYPQAGLIRRSLPNMSHSMLVHEPAKIYPYHLLLITN---YRLPSDVDR 803
            .|.:||.....|.             |:|||.      || ||:||.:|::||   .::..||||
  Rat   778 DGHMPAMRMDRGV-------------SMPNML------EP-KIFPYEMLMVTNRGRNKILRDVDR 822

  Fly   804 CNLERHLSDIEFEHILQCARSEFYRLPQWRRNELKRRVKLF 844
            ..|||||:...|..|...:..||.:||.||||::|::.|||
  Rat   823 TRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Unc-115a	NP_001163573.1	LIM1_abLIM	46..97	CDD:188713	26/50 (52%)
		LIM2_abLIM	102..157	CDD:188714	28/54 (52%)
		LIM3_abLIM	211..262	CDD:188715	33/50 (66%)
		LIM4_abLIM	270..326	CDD:188716	34/87 (39%)
		VHP	809..844	CDD:460493	14/34 (41%)
Ablim1	NP_001382083.1	LIM1_abLIM	100..151	CDD:188713	26/50 (52%)
		LIM2_abLIM	156..211	CDD:188714	28/54 (52%)
		LIM3_abLIM	227..278	CDD:188715	33/50 (66%)
		LIM4_abLIM	286..341	CDD:188716	33/55 (60%)
		AbLIM_anchor	394..813	CDD:465046	135/573 (24%)
		VHP	828..863	CDD:128458	14/34 (41%)