Protein Alignment CG31495 and Nvl

DIOPT Version :10

• Sequence 1: NP_731866.1
• Gene: CG31495 / 261626
• FlyBaseID: FBgn0051495
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_080447.1
• Gene: Nvl / 67459
• MGIID: 1914709
• Length: 855
• Species: Mus musculus
• Alignment Length: 218
• Identity: 42/218 - (19%)
• Similarity: 83/218 - (38%)
• Gaps: 54/218 - (24%)

  Fly   129 LVEGKPKSGLTTVAAQMALKTDCPFIKYISSAELLGLSDSEKCQRIREVLEDAYVSRRSCVIIDD 193
            |:.|.|..|.|.:|..:|.:.|.|.:| :::.|::.....|..|::||:.:.| ||...|::
Mouse   301 LLHGPPGCGKTLLAHAIAGELDLPILK-VAAPEIVSGVSGESEQKLRELFDQA-VSNAPCIV--- 360

  Fly   194 FERVIGYGALGKRYSKEFLQKLTVLLKKQPPNSHELIIICTSNRLDVLEELGLLSVFTSVHNVPN 258
                             |:.::..:..|:...|.::.....:..|..:::|..::....|..:..
Mouse   361 -----------------FIDEIDAITPKREVASKDMERRIVAQLLTCMDDLNNVAATARVLVIGA 408

  Fly   259 VSTPKELMVIVEASKRFEPEELRQIEIAMDGRNVSIGIKRLLDLIAWVNSLNPDRRAAK-----L 318
            .:.|..|...:..:.||:             |.|.:||              ||..|.:     |
Mouse   409 TNRPDSLDPALRRAGRFD-------------REVCLGI--------------PDEAARERILQTL 446

  Fly   319 LKKLGEAMGWVGNHSSPLVPQYI 341
            .:||.....:...|.:.|.|.::
Mouse   447 CRKLRLPETFNFCHLAHLTPGFV 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31495	NP_731866.1	SpoVK	<1..88	CDD:440232
		AAA	129..257	CDD:459627	25/127 (20%)
Nvl	NP_080447.1	Interaction with RPL5. /evidence=ECO:0000250|UniProtKB:O15381	1..219
		Nucleolin_bd	2..72	CDD:465247
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:21474449	49..52
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..234
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:O15381	85..88
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:O15381	217..231
		CDC48	<242..855	CDD:273521	42/218 (19%)
		Interaction with WDR74. /evidence=ECO:0000250|UniProtKB:O15381	266..473		42/218 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	496..523