Protein Alignment Pgant4 and GALNT4

DIOPT Version :9

• Sequence 1: NP_001137779.1
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_003765.2
• Gene: GALNT4 / 8693
• HGNCID: 4126
• Length: 578
• Species: Homo sapiens
• Alignment Length: 566
• Identity: 199/566 - (35%)
• Similarity: 301/566 - (53%)
• Gaps: 51/566 - (9%)

  Fly    85 RSDKLQGFRLPEPKGERKDWHD--YAAMEADRKRSGFGEHGVAVKIE-NPDEKQLEKEHYEMNGF 146
            |:.:|...||.:.:...:|...  |....||.:  ..||.|.|.|:: |.||.:.::|..|....
Human    40 RARELGSRRLSDLQKNTEDLSRPLYKKPPADSR--ALGEWGKASKLQLNEDELKQQEELIERYAI 102

  Fly   147 NGLISDRISVNRSVPDLRLEACKTRKY-LAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELL 210
            |..:|||||::|.:.|.|:..||::|: ...||..|||..|:||.::||||:|:||:..:|..||
Human   103 NIYLSDRISLHRHIEDKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLL 167

  Fly   211 KQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHI 275
            |:|:||||.|:...||..|:.|:..  ...|.::|..:|:||:.||:.||..|.|.|:.|.|.|.
Human   168 KEIILVDDLSDRVYLKTQLETYISN--LDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHC 230

  Fly   276 EVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDAL 340
            |.|..||.||:|.|..:.....||::|||....|.::....:...|||||::.: |...:|:...
Human   231 ECNSGWLEPLLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDWRLTF-QWHSVPKQER 294

  Fly   341 DKSM----PYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSR 401
            |:.:    |.|||.|.|||||::..:|..||.||..:::||||..||||::|.|||.|...|||.
Human   295 DRRISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSH 359

  Fly   402 VAHIFRGPMK-PRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKRDP----KTYDNLDAGDLTRQR 461
            |.|:|  |.: |...|   ||: :|..|.|||||||||::.|.|:|    :.|     ||::.::
Human   360 VGHVF--PKRAPYARP---NFL-QNTARAAEVWMDEYKEHFYNRNPPARKEAY-----GDISERK 413

  Fly   462 GVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNM---GKSTEEAVGM 523
            .:||||:||||.|::..|.|:..|   |.:.|.: .|.|::......|||..   ...|...:.:
Human   414 LLRERLRCKSFDWYLKNVFPNLHV---PEDRPGW-HGAIRSRGISSECLDYNSPDNNPTGANLSL 474

  Fly   524 FSCADNRTHPQ-PNQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQG----GNQFWY 583
            |.|     |.| .|||:|.:..:::|......:|.:|.|  ....|.|.:|...|    .|..|:
Human   475 FGC-----HGQGGNQFFEYTSNKEIRFNSVTELCAEVPE--QKNYVGMQNCPKDGFPVPANIIWH 532

  Fly   584 YDRQTQRLVHGENNKRCLEGF-VENGIAKVVANSCENGNDRQRWEF 628
            : ::...:.| .::..||..: ...|...|...:|:..:..|.|.|
Human   533 F-KEDGTIFH-PHSGLCLSAYRTPEGRPDVQMRTCDALDKNQIWSF 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	99/238 (42%)
		pp-GalNAc-T	181..480	CDD:133004	129/307 (42%)
		Ricin_B_lectin	496..626	CDD:279046	31/138 (22%)
		RICIN	498..628	CDD:238092	32/138 (23%)
GALNT4	NP_003765.2	Catalytic subdomain A	134..243		50/110 (45%)
		pp-GalNAc-T	138..432	CDD:133004	129/307 (42%)
		Catalytic subdomain B	303..365		34/63 (54%)
		Ricin_B_lectin	446..574	CDD:395527	31/136 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810