Protein Alignment Pgant4 and Galntl5

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_080725.2
• Gene: Galntl5 / 67909
• MGIID: 1915159
• Length: 431
• Species: Mus musculus
• Alignment Length: 402
• Identity: 154/402 - (38%)
• Similarity: 223/402 - (55%)
• Gaps: 54/402 - (13%)

  Fly   128 IENPDEKQLEKE-----------------HYEMN-------------GFNGLISDRISVNRSVPD 162
            :||..|:.|:|.                 |.|:|             |.|.::|.|:.:.|.|||
Mouse    35 LENEKEELLKKRSLGKNAHQQTRHSEDVTHDEVNFSDPELIQGLRRYGLNAIMSRRLGIEREVPD 99

  Fly   163 LRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQ 227
            .|.:.|:.:.|...||..|:|..|:||.||||||::.||:|.:|..||::|:||||.||:|.||.
Mouse   100 SRDKICQQKHYPFNLPTASIIICFYNEEFNTLLRAVSSVVNLSPQHLLEEIILVDDMSEFDDLKD 164

  Fly   228 PLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAIN 292
            .||.|: :.|...|.::||.:|:|||.:::.||..|.|.::||.|||.|||..||.||:..||.:
Mouse   165 KLDYYL-EIFRGKVKLIRNKKREGLIRSKMIGASRASGDILVFLDSHCEVNRVWLEPLLHAIAKD 228

  Fly   293 PKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVL------PEDALDKSMPYRSPVM 351
            .|:..||::|.|:.....|.:.  ...||.|||.:..:...|.      ||   ..|.|.|||.|
Mouse   229 HKMVVCPIIDVINELTLDYMAA--PIVRGAFDWNLNLRWDNVFAYELDGPE---GPSTPIRSPAM 288

  Fly   352 MGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNP 416
            .||:||||..:|.:||.||:.:||.|||..|||.:||||||.|..:|||||.:..:...:.|  .
Mouse   289 TGGIFAINRHYFNELGQYDNGMDICGGENVELSLRIWMCGGQLFILPCSRVGYNSKALSQHR--R 351

  Fly   417 RGHNFVAKNHKRVAEVWMDEYK-QYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVA 480
            ...:.:::|..||..||:|||| .:..:|...||  :..|:::.:..:|:||.||||.|::..:
Mouse   352 ANQSALSRNLLRVVHVWLDEYKGNFFLQRPSLTY--VSCGNISERVELRKRLGCKSFQWYLDNI- 413

  Fly   481 PDFLVKFPPVEP 492
                  ||.:||
Mouse   414 ------FPELEP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	129/305 (42%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	154/402 (38%)
Galntl5	NP_080725.2	Catalytic subdomain A	114..224		56/110 (51%)
		pp-GalNAc-T	118..414	CDD:133004	129/312 (41%)
		Catalytic subdomain B	282..344		36/61 (59%)