Protein Alignment Pgant4 and GALNT16

DIOPT Version :9

• Sequence 1: NP_001137779.1
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001161840.1
• Gene: GALNT16 / 57452
• HGNCID: 23233
• Length: 558
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 190/513 - (37%)
• Similarity: 281/513 - (54%)
• Gaps: 43/513 - (8%)

  Fly   134 KQLE--KEHYEMNGFNGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLR 196
            |||:  ::.|..:.||.|.||::|.:|.:.|.|..:|.:..|.:.||..|||..|.||..:||||
Human    77 KQLKAGEDPYRQHAFNQLESDKLSPDRPIRDTRHYSCPSVSYSSDLPATSVIITFHNEARSTLLR 141

  Fly   197 SIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAK 261
            ::.||:||||..|:::|:||||.|     ..|.|..:....|. |..:||..|:|||.:|:.||.
Human   142 TVKSVLNRTPANLIQEIILVDDFS-----SDPEDCLLLTRIPK-VKCLRNDRREGLIRSRVRGAD 200

  Fly   262 VAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWK 326
            ||...|:.|.|||.|||..||||:::.:..:......|::|.||.::|:|.:.:.| .||||||.
Human   201 VAAATVLTFLDSHCEVNTEWLPPMLQRVKEDHTRVVSPIIDVISLDNFAYLAASAD-LRGGFDWS 264

  Fly   327 MLYK--QLPVLPEDAL---DKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFK 386
            :.:|  |:|:  |..:   |.:.|.|:||:.||:|.|:..:|..||.||.|:||||||.:||||:
Human   265 LHFKWEQIPL--EQKMTRTDPTRPIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIWGGENFELSFR 327

  Fly   387 IWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGHNFV-AKNHKRVAEVWMDEYKQYVYKRDPKTYD 450
            :|||||.|..||||||.|:|| ...|...|.|:... .:|.||.|||||||||||.|:..|....
Human   328 VWMCGGSLEIVPCSRVGHVFR-KRHPYNFPEGNALTYIRNTKRTAEVWMDEYKQYYYEARPSAIG 391

  Fly   451 NLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGK 515
            .. .|.:..:...|:::.||||.|::..|.|:..|......|     |||:...|   ||::.|:
Human   392 KA-FGSVATRIEQRKKMNCKSFRWYLENVYPELTVPVKEALP-----GIIKQGVN---CLESQGQ 447

  Fly   516 ST--EEAVGMFSCADNRTHPQPNQFWELSIFRD--LRMKGFDSVCLDVHEGPPNATVWMWSCHSQ 576
            :|  :..:||..|..:..:|||.|.|   :|.|  ::.:|............|.:.|.:..|:.:
Human   448 NTAGDFLLGMGICRGSAKNPQPAQAW---LFSDHLIQQQGKCLAATSTLMSSPGSPVILQMCNPR 509

  Fly   577 GGNQFWYYDRQTQRLVHGENNKRCLEGFVENGIAKVVANSCENGNDRQRWEFGFVNHT 634
            .|.|.|   |:....:....:..||    |...|::|.:.|:.....|:|:  .:.||
Human   510 EGKQKW---RRKGSFIQHSVSGLCL----ETKPAQLVTSKCQADAQAQQWQ--LLPHT 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	106/238 (45%)
		pp-GalNAc-T	181..480	CDD:133004	133/304 (44%)
		Ricin_B_lectin	496..626	CDD:279046	33/133 (25%)
		RICIN	498..628	CDD:238092	34/133 (26%)
GALNT16	NP_001161840.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..54
		Catalytic subdomain A	122..227		52/110 (47%)
		pp-GalNAc-T	126..420	CDD:133004	133/304 (44%)
		Catalytic subdomain B	286..348		37/61 (61%)
		Ricin_B_lectin	441..543	CDD:395527	27/111 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152442
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740