DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant4 and galnt13

DIOPT Version :9

Sequence 1:	NP_001137779.1	Gene:	Pgant4 / 261610	FlyBaseID:	FBgn0051956	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	XP_031748551.1	Gene:	galnt13 / 550031	XenbaseID:	XB-GENE-1012445	Length:	571	Species:	Xenopus tropicalis

Alignment Length:	553	Identity:	229/553 - (41%)
Similarity:	326/553 - (58%)	Gaps:	42/553 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ERKDWHDYAAMEA--DRKRSGFGEHGVAVKIENPDEKQLEKEHYEMNGFNGLISDRISVNRSVPD 162
            :|||.....|:.|  .|...|.||.|.||.|...|:::: ||.:::|.||.:.||.|::|||:||
Frog    36 DRKDRSLLPALRAVISRTPEGPGELGKAVIIPKDDQEKM-KELFKINQFNLMASDLIALNRSLPD 99

  Fly   163 LRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQ 227
            :|||.|||:.|..:|||.|::.:|.||.::||||:::|||||:|..|:.:|:||||.||.|.||.
Frog   100 VRLEGCKTKVYPDELPNTSIVIVFHNEAWSTLLRTVHSVINRSPHRLISEIILVDDSSERDFLKS 164

  Fly   228 PLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAIN 292
            ||::|| :|....|.|:|..:|.|||.||:.||.||.||::.|.|:|.|....||.||:..|..:
Frog   165 PLENYV-KHLEVPVKILRMEQRSGLIRARLRGANVAKGQIITFLDAHCECTIGWLEPLLARIKED 228

  Fly   293 PKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDAL-----DKSMPYRSPVMM 352
            .|...||::|.||.:.|.|.:|: |...|||:||:.::..|| |:..:     |:::|.|:|.|.
Frog   229 RKTVVCPIIDVISDDTFEYMAGS-DMTYGGFNWKLNFRWYPV-PQREMDRRKGDRTLPVRTPTMA 291

  Fly   353 GGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMK---PRG 414
            ||||:|:..:|.:||.||..:||||||..|:||:||.|||.|..|.||.|.|:||....   |.|
Frog   292 GGLFSIDKTYFEELGTYDSGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGG 356

  Fly   415 NPRGHNFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEV 479
            .  || .:.||::|:||||||::|.:.|...|... .:|.||::.::.:||.|||..|.|::..|
Frog   357 T--GH-VINKNNRRLAEVWMDDFKDFFYIISPGVV-KVDYGDVSERKALRENLKCNPFSWYLETV 417

  Fly   480 APDFLVKFPPVEPPSY-AAGIIQNVANPVYCLDNMGKSTEEAVGMFSCADNRTHPQ-PNQFWELS 542
            .||..:      |..| :.|.|:||... .||||||:...|.||:|:|     |.. .||.:..:
Frog   418 YPDSQI------PRRYFSLGEIRNVETN-QCLDNMGRKENEKVGIFNC-----HGMGGNQVFSYT 470

  Fly   543 IFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRCLE-GFVE 606
            ..:::|.   |.:||||..  .|..|.|..||...|||.|.||.:|...:| ...:.||. ..||
Frog   471 ADKEIRT---DDLCLDVSR--LNGPVIMLKCHHMRGNQLWEYDAETHTFLH-IITQSCLTLSNVE 529

  Fly   607 NGIAKVVANSCENGNDRQRWEFGFVNHTMLDTF 639
            :|........| ||.::|||...  |:|.|:.|
Frog   530 DGTFGPTVEFC-NGRNQQRWTLR--NYTRLEVF 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	111/238 (47%)
		pp-GalNAc-T	181..480	CDD:133004	135/306 (44%)
		Ricin_B_lectin	496..626	CDD:279046	46/131 (35%)
		RICIN	498..628	CDD:238092	48/131 (37%)
galnt13	XP_031748551.1	pp-GalNAc-T	118..418	CDD:133004	135/306 (44%)
galnt13	XP_031748551.1	Ricin_B_lectin	431..548	CDD:395527	46/129 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910