Protein Alignment Pgant4 and GALNT7

DIOPT Version :9

• Sequence 1: NP_001137779.1
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001362528.1
• Gene: GALNT7 / 51809
• HGNCID: 4129
• Length: 657
• Species: Homo sapiens
• Alignment Length: 555
• Identity: 211/555 - (38%)
• Similarity: 305/555 - (54%)
• Gaps: 56/555 - (10%)

  Fly    95 PEPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEHYEMNGFNGLISDRISVNRS 159
            |||.|               ...|.||....: :..|:.||..:...:..|||.:.||.||::||
Human   140 PEPPG---------------VVGGPGEKAKPL-VLGPEFKQAIQASIKEFGFNMVASDMISLDRS 188

  Fly   160 VPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDV 224
            |.|||.|.||...|...|...||:.:|.||.::||:|:::|||.|||.:.|.:|||:||.|..:.
Human   189 VNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEH 253

  Fly   225 LKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGA-KVAVGQVMVFFDSHIEVNYNWLPPLIEP 288
            ||:.||:|::. :..||.:.||..|:|||.||..|| |..:|||:::.|:|.||..||..||:.|
Human   254 LKEKLDEYIKL-WNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAP 317

  Fly   289 IAINPKISTCPMVDTISHEDFS---YFSGNKDG-ARGGFDWKMLYKQLPVLPEDAL---DKSMPY 346
            |:.:....|.|::|.|...|:|   ...|::|| |||.:||.:|:|::|:..::..   .|:.||
Human   318 ISKDRTTCTVPLIDYIDGNDYSIEPQQGGDEDGFARGAWDWSLLWKRIPLSHKEKAKRKHKTEPY 382

  Fly   347 RSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFR--GP 409
            |||.|.||||||..:||::||.||..|.|||||.:|:|:|||.|||.||.||||||.||:|  |
Human   383 RSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEG- 446

  Fly   410 MKPRGNPR----GHNFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRERLKCK 470
              .:|||.    |.:...||:.||.|||.||||.|.|...|:: ..|..||::..:..||...||
Human   447 --WQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYFYASRPES-QALPYGDISELKKFREDHNCK 508

  Fly   471 SFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKSTEEAVGMFSCADNRTHPQ- 534
            ||.|||.|:|.|....: |:.|.:...|.|:.. ...||:|:|||:....|.:..|     |..
Human   509 SFKWFMEEIAYDITSHY-PLPPKNVDWGEIRGF-ETAYCIDSMGKTNGGFVELGPC-----HRMG 566

  Fly   535 PNQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQF--WYYDRQTQRLVHGENN 597
            .||.:.::....|..  :|. ||.  :|...:.|.:..|:.   |:|  |.|.:...|..|..:.
Human   567 GNQLFRINEANQLMQ--YDQ-CLT--KGADGSKVMITHCNL---NEFKEWQYFKNLHRFTHIPSG 623

  Fly   598 KRCLEGFVENGIAKVVANSCENGNDRQRWEFGFVN 632
            | ||:.  ...:.:|..::|::....|:||...::
Human   624 K-CLDR--SEVLHQVFISNCDSSKTTQKWEMNNIH 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	112/241 (46%)
		pp-GalNAc-T	181..480	CDD:133004	145/312 (46%)
		Ricin_B_lectin	496..626	CDD:279046	32/132 (24%)
		RICIN	498..628	CDD:238092	33/132 (25%)
GALNT7	NP_001362528.1	pp-GalNAc-T	210..518	CDD:133004	145/312 (46%)
		Ricin_B_lectin	534..649	CDD:366226	32/131 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48703
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820