Protein Alignment Pgant4 and Pgant35A

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_652069.2
• Gene: Pgant35A / 48775
• FlyBaseID: FBgn0001970
• Length: 632
• Species: Drosophila melanogaster
• Alignment Length: 676
• Identity: 217/676 - (32%)
• Similarity: 306/676 - (45%)
• Gaps: 140/676 - (20%)

  Fly     8 VKRLLRK-----------VVLLLVVIVTVSLVTTL------VVERRMKNAAELTEQ------LDP 49
            :||||.|           |.||.::..:.||.:::      :.|......|||:.|      ..|
  Fly     4 IKRLLCKSCGLGTLLVAVVWLLALLFYSHSLRSSIRSAGWRIDEGNATPRAELSYQARVTVGCTP 68

  Fly    50 NGDPITPVFRAANIHPTRKAPRPPFQDRNSVVDIPRSDKLQGFRLPEPKGERKDWHDYAAMEADR 114
            |....|....|        ||:||..        |...:|.|.
  Fly    69 NASITTGESPA--------APKPPSD--------PEQLELLGV---------------------- 95

  Fly   115 KRSGFGEHGVAVKIENPDEKQLEKEHYEMNGFNGLISDRISVNRSVPDLRLEACKTRK--YLAKL 177
                         :.|..:|.:....|:.:.||.|:|:.|.:.|::||.|.:.|..::  ....|
  Fly    96 -------------VRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENL 147

  Fly   178 PNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPH-LV 241
            |..|::..|:|||..||:|||.:|:.|||..||::|:||||.|:...|:..|...::....: .:
  Fly   148 PQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNL 212

  Fly   242 TIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISH 306
            ..::|.:|:|||.:|:.||:.|||.|:||.|||||||..||.||:..|.........|::|.|:.
  Fly   213 RYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINA 277

  Fly   307 EDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDAL----DKSMPYRSPVMMGGLFAINTDFFWDLG 367
            :.|.|.....  .||||:|. |:.:...|||..|    |...|:|||.|.|||||:|..:|..||
  Fly   278 DTFEYTPSPL--VRGGFNWG-LHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLG 339

  Fly   368 GYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGHNFVAKNHKRVAEV 432
            .||..:||||||..|:||:.|.|||.:..||||||.|||| ..:|..:|.|.|.:.||..|:|.|
  Fly   340 EYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFR-KRRPYTSPDGANTMLKNSLRLAHV 403

  Fly   433 WMDEYKQYVYKRD--PKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVE-PPS 494
            |||:||.|..|.:  ||||   |.||::.:..:||||:|:.|.|::..|.|:..|  |..| ..|
  Fly   404 WMDQYKDYYLKHEKVPKTY---DYGDISDRLKLRERLQCRDFAWYLKNVYPELHV--PGEESKKS 463

  Fly   495 YAAGIIQN-------------------------VANPVYCLDNMGKSTEEAVGMFSCADNRTHPQ 534
            .||.|.|.                         ||..|......|.|.:    :.:|  .||
  Fly   464 AAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQ----LQTC--RRT--- 519

  Fly   535 PNQFW----ELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGE 595
            |||.|    :..|..|      ..:||   |...:|.|.:..||...|:|.|.:.|.....|:..
  Fly   520 PNQLWYETEKAEIVLD------KLLCL---EASGDAQVTVNKCHEMLGDQQWRHTRNANSPVYNM 575

  Fly   596 NNKRCLEGFVENGIAKVVANSCENGN 621
            ....||........|.:..:.|...|
  Fly   576 AKGTCLRAAAPTTGALISLDLCSKSN 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	135/305 (44%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	36/158 (23%)
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	135/305 (44%)
		beta-trefoil_Ricin_GALNT11	478..609	CDD:467318	31/142 (22%)