DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant4 and galnt6

DIOPT Version :9

Sequence 1:	NP_001137779.1	Gene:	Pgant4 / 261610	FlyBaseID:	FBgn0051956	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_998361.1	Gene:	galnt6 / 406477	ZFINID:	ZDB-GENE-040426-2272	Length:	619	Species:	Danio rerio

Alignment Length:	674	Identity:	207/674 - (30%)
Similarity:	329/674 - (48%)	Gaps:	112/674 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RLLRKVVLLLVVIV--TVSLVTTLVVERRMKNAA-----------------ELTEQLDPN----- 50
            ||.|::..|.:.||  |:.::..:|::|.:.:.|                 |:......|
Zfish     2 RLRRRLSPLKLAIVGGTLFMLILVVLQRDVNSGALQDPWLQDLSNKKERVFEMVRGAVNNFAFQI 66

  Fly    51 GDPITPVFRAANIHPTRKAPRPPFQDRNSVVDIPRSDKLQGFRLPEPKG-----ERKDWHDYAAM 110
            |.|:.|   :..:.||        .|||.                 |.|     |.|.|.:
Zfish    67 GAPVRP---SVEVQPT--------PDRNC-----------------PSGFYTQRELKPWIE---- 99

  Fly   111 EADRKRSGFGEHGVAVKIENPDEKQLEKEHYE---MNGFNGLISDRISVNRSV-PDLRLEACKTR 171
            .........|..||..:.:.. .|:.|||..|   .:.||...|||||::|:: .|.|...|..|
Zfish   100 RPPENPQAPGADGVPFQYDRM-TKEEEKEKQEGMTRHCFNQFASDRISLHRTLGDDTRPPECVDR 163

  Fly   172 KY--LAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQ 234
            |:  ...||..|||.:|.||.::||||::|||::.:|...||:|::|||.|..:.|...|::||:
Zfish   164 KFRRCPALPTTSVIIVFHNEAWSTLLRTVYSVLHTSPAAFLKEIIMVDDASTAEHLHGKLEEYVK 228

  Fly   235 QHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCP 299
            .  ..:|.:||.|||:|||.||:.||..|.|:::.|.|:|.|..:.||.||:..|...|.....|
Zfish   229 A--LKIVKVVRQPERKGLITARLLGASKAEGEILTFLDAHCECFHGWLEPLLARIVEEPTAVVSP 291

  Fly   300 MVDTISHEDFSYFSGNKDGA------RGGFDWKMLY--KQLPVLPEDA--LDKSMPYRSPVMMGG 354
            .:.||   |.:.|..:|..|      ||.|||.:.:  :.:|.. |:|  .|::.|.::|...||
Zfish   292 EITTI---DLNTFQFHKPVATARAHNRGNFDWSLTFGWEGIPDY-ENAKRKDETYPVKTPTFAGG 352

  Fly   355 LFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGH 419
            ||:|:..:|..:|.|||:::|||||..|:||::|.|||.|..:|||.|.|:|| ...|...|:|.
Zfish   353 LFSISKAYFEKIGTYDDKMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFR-TKSPHTFPKGT 416

  Fly   420 NFVAKNHKRVAEVWMDEYKQYVYKRD---PKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAP 481
            ..:.:|..|:||||||:||...|:|.   .|.......||::.:..:||.|:||:|.|:::.|.|
Zfish   417 EVITRNQVRLAEVWMDDYKLIFYRRSQSAAKMAKEKGFGDISDRLKLREDLQCKNFSWYLSNVYP 481

  Fly   482 DFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKSTE--EAVGMFSCADNRTHPQ-PNQFWELSI 543
            :..|  |.:.|..:  |.::| .....||| :|:|..  :.|.|::|     |.. .||::|.:.
Zfish   482 EAFV--PDLSPVKF--GALKN-RGAQQCLD-VGESNNGGKPVIMYTC-----HNMGGNQYFEYTS 535

  Fly   544 FRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGN----QFWYYDRQTQRLVHGENNKRCLEGF 604
            .::||......:||.....|....:.:.:...:|.:    |.|....  ::|:...::.:||.
Zfish   536 HKELRHNIGKQLCLQASPYPEPVKIELCTLKGKGSSLAPEQEWLITE--EQLLKNPSSGKCLH-- 596

  Fly   605 VENGIAKVVANSCENGNDRQRWEF 628
             :.| .|::.:.|...:..|:|.|
Zfish   597 -KKG-DKILMSPCNPDDHHQQWAF 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	98/245 (40%)
		pp-GalNAc-T	181..480	CDD:133004	123/311 (40%)
		Ricin_B_lectin	496..626	CDD:279046	29/136 (21%)
		RICIN	498..628	CDD:238092	30/136 (22%)
galnt6	NP_998361.1	pp-GalNAc-T	175..480	CDD:133004	123/311 (40%)
		Ricin_B_lectin	493..616	CDD:279046	29/137 (21%)
		RICIN	494..618	CDD:238092	30/136 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586976
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740