Protein Alignment Pgant4 and Galntl6

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001129228.1
• Gene: Galntl6 / 361142
• RGDID: 1564773
• Length: 601
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 266/650 - (40%)
• Similarity: 362/650 - (55%)
• Gaps: 75/650 - (11%)

  Fly     5 KRYVKRLLRKVVLLLVVIV---TVSLVTTLVVERRMKNAAELTEQLDPNGDPITPVFRAANIHPT 66
            ||..||.|:..:|..|.::   .:.|.:....:..||:|.....|..|.|
  Rat     2 KRKQKRFLQMTLLFTVALIFLPNIGLWSLYKDKHLMKSAEPAEHQTFPLG--------------- 51

  Fly    67 RKAPRPPFQDRNSVVDIPRSDKLQGFRLPEPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIENP 131
                         :.|........|.|       |||||||.:::.|..|||.||||....:...
  Rat    52 -------------LGDGQFYSWTDGLR-------RKDWHDYVSIQKDALRSGKGEHGKPYPLTEE 96

  Fly   132 DEKQLEKEHYEMNGFNGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLR 196
            |.   :...|..||||..:|:.|::.||:||:|...||.:.||.:|||.|:|..|.||.:.:|||
  Rat    97 DH---DDSAYRENGFNIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLR 158

  Fly   197 SIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAK 261
            :|:|:|||||..|:.:|:||||.|:.:.||..|:||:.: || :|.|||..:|:|||..|:.||.
  Rat   159 TIHSIINRTPESLIAEIILVDDFSDREHLKDKLEDYMAR-FP-IVRIVRTKKREGLIRTRLLGAS 221

  Fly   262 VAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWK 326
            ||.|:|:.|.|||.|||.||||||:..||:|.|...|||:|.|.|..|.|.:...|..||.|||:
  Rat   222 VARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHSHFGYEAQAGDAMRGAFDWE 286

  Fly   327 MLYKQLPVLPE-DALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMC 390
            |.||::|:.|| ...|.|.|:.||||.|||||::..:||:|||||..|:||||||||:|||:|||
  Rat   287 MYYKRIPIPPELQRADPSEPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMC 351

  Fly   391 GGMLLDVPCSRVAHIFRG--PMK-PRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNL 452
            ||.:.|||||||.||:|.  |.| |.|..     :|:|.|||||.||||:.:|:|:|.|: |.:|
  Rat   352 GGEMFDVPCSRVGHIYRKYVPYKVPSGTS-----LARNLKRVAETWMDEFAEYIYQRRPE-YRHL 410

  Fly   453 DAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKST 517
            ..||::.|:.:|:|||||.|.|||..||.|....:|||||...|.|.|:|||..: |:|:...:.
  Rat   411 STGDISAQKELRKRLKCKDFKWFMAAVAWDVPKYYPPVEPLPAAWGEIRNVAANL-CVDSKHGAM 474

  Fly   518 EEAVGMFSC---ADNRT--HPQPNQF-WELSI--FRDLRMKGFDSVCLDV--HEGPPNATVWMWS 572
            ...:.:..|   ...||  |.|...| |...|  ...|..:.|   |||.  |..|    |.::.
  Rat   475 GTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKF---CLDAISHSSP----VTLYD 532

  Fly   573 CHSQGGNQFWYYDRQTQRLVHGENNKRCLEGFVENGIAKVVANSCENGNDRQRWEFGFVNHTMLD 637
            ||...|||.|.| |:.:.|.|..:|. |::  ......||....|:..::.|:|.|..:|.|:|:
  Rat   533 CHGMKGNQLWGY-REDRTLFHPVSNS-CMD--CNPAEKKVFMARCDPLSETQQWMFEHINMTVLE 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	161/302 (53%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	41/145 (28%)
Galntl6	NP_001129228.1	pp-GalNAc-T	143..438	CDD:133004	161/302 (53%)
		beta-trefoil_Ricin_GALNTL6	449..594	CDD:467355	47/156 (30%)