DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant4 and Pgant7

DIOPT Version :9

Sequence 1:	NP_001137779.1	Gene:	Pgant4 / 261610	FlyBaseID:	FBgn0051956	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_001285406.1	Gene:	Pgant7 / 32836	FlyBaseID:	FBgn0030930	Length:	591	Species:	Drosophila melanogaster

Alignment Length:	573	Identity:	217/573 - (37%)
Similarity:	310/573 - (54%)	Gaps:	76/573 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 DIPR-SDKLQGFRLPEPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEHYEMNG 145
            ::|: .|.|..|   |||..             :.|||.||:|.|..: :||:|.:........|
  Fly    62 EVPKLVDGLGNF---EPKDV-------------KPRSGPGENGEAHSL-SPDKKHMSDASEMEYG 109

  Fly   146 FNGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELL 210
            .|...||.||::|||.|.|||.|:...|...||..|||.:|.||.|:.|:|:::|||:|:|..:|
  Fly   110 MNIACSDEISMHRSVRDTRLEECRHWDYPFDLPRTSVIIVFHNEGFSVLMRTVHSVIDRSPTHML 174

  Fly   211 KQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHI 275
            .:|:||||.|:.:.|:..||:||.| |..||.::||.||:|||..|..||..|.|:|:||.|:|.
  Fly   175 HEIILVDDFSDKENLRSQLDEYVLQ-FKGLVKVIRNKEREGLIRTRSRGAMEATGEVIVFLDAHC 238

  Fly   276 EVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSY--FSGNKDGARGGFDWKMLYKQLPVLPED 338
            |||.||||||:.||..:..:.|.|::|.|.|::|.|  ..|..:..||.|:|.||||:..|...:
  Fly   239 EVNTNWLPPLLAPIYRDRTVMTVPIIDGIDHKNFEYRPVYGTDNHFRGIFEWGMLYKENEVPRRE 303

  Fly   339 ---ALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCS 400
               ....|.|||||...|||||||.::|.:||.||..|.:||||.:|||||||.|||.:..||||
  Fly   304 QRRRAHNSEPYRSPTHAGGLFAINREYFLELGAYDPGLLVWGGENFELSFKIWQCGGSIEWVPCS 368

  Fly   401 RVAHIFRGPMKPRGNPRGHNF-----------VAKNHKRVAEVWMDE-YKQYVYKRDP-KTYDNL 452
            ||.|::||.|.       :||           :..|:|||.|.|.|: :|:|.|.|:| ..|  |
  Fly   369 RVGHVYRGFMP-------YNFGKLASKKKGPLITINYKRVIETWFDDTHKEYFYTREPLARY--L 424

  Fly   453 DAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKST 517
            |.||::.|..:::||.||||.|||..:|.|...|||.: |.:...|.:::||:. .|||:||...
  Fly   425 DMGDISEQLALKKRLNCKSFQWFMDHIAYDVYDKFPGL-PANLHWGELRSVASD-GCLDSMGHQP 487

  Fly   518 EEAVGMFSC--ADNRTHPQPNQFWELSIFR---DLRMKGFD-SVC-LDVHEGPPNATVWMWSCHS 575
            ...:|:..|  ..|....:.|...:|.:..   :...:|.. :|| |...:||
  Fly   488 PAIMGLTYCHGGGNNQLVRLNAAGQLGVGERCVEADRQGIKLAVCRLGTVDGP------------ 540

  Fly   576 QGGNQFWYYDRQTQRLVHGENNKRCLEGFVENGIAKVVANSCENGNDRQRWEF 628
                  |.|:..|:.|:| ..:|:|:.  :.....::....|:..:..|:|.|
  Fly   541 ------WQYNEHTKHLMH-RVHKKCMA--LHPATQQLSLGHCDVNDSYQQWWF 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	116/238 (49%)
		pp-GalNAc-T	181..480	CDD:133004	147/316 (47%)
		Ricin_B_lectin	496..626	CDD:279046	28/136 (21%)
		RICIN	498..628	CDD:238092	29/136 (21%)
Pgant7	NP_001285406.1	Glyco_tranf_2_3	142..373	CDD:290369	115/231 (50%)
		pp-GalNAc-T	145..452	CDD:133004	147/316 (47%)
		Ricin_B_lectin	468..582	CDD:279046	28/135 (21%)
		RICIN	469..584	CDD:238092	29/136 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457028
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48703
OrthoDB	1	1.010	-	-		D60373at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.860