Protein Alignment Pgant4 and Galnt18

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001073353.1
• Gene: Galnt18 / 293181
• RGDID: 1309623
• Length: 607
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 183/613 - (29%)
• Similarity: 285/613 - (46%)
• Gaps: 132/613 - (21%)

  Fly    84 PRSDKLQGFRLPEPKG------ERKDWH----------------DYAAMEADRKRSGFGEHGVAV 126
            |..||    :|.|.||      ||.| |                :.|..|.....|.|...|..:
  Rat    46 PAPDK----KLEEDKGDTLKIIERLD-HLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQEL 105

  Fly   127 KIENPDEKQLEKEHYEMNGFNGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHF 191
               :|:.:::..:.::..|:|..:|||:.::|.:||||...|:...:...||.:|::|||.||..
  Rat   106 ---SPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEAL 167

  Fly   192 NTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQ---HFPHLVTIVRNPERQGLI 253
            :.|||||:|.:.|||..|||:|:||||.|..:.||:.|.:||.:   ..|..:.:||:.:::|||
  Rat   168 SVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLI 232

  Fly   254 GARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDG 318
            .:|::|.:.|...|:..||:|:|.|..|..|::..|..|.|....|..|.|.:::|..  .....
  Rat   233 RSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEI--EEYPL 295

  Fly   319 ARGGFDWKMLYKQLPVLPEDA---LDKS-MPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGE 379
            |..||||::..:.|.  |..|   |:.| .|.|||.:: |.|.::..:|.::|..|:.::::|||
  Rat   296 AAQGFDWELWCRYLN--PPKAWWKLENSTAPIRSPALI-GCFIVDRQYFEEIGLLDEGMEVYGGE 357

  Fly   380 QYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYK- 443
            ..||..::|.|||.:..:||||:|||.|.......:...|  |.:|..|||||||||:|.:||.
  Rat   358 NVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAH--VRRNALRVAEVWMDEFKSHVYMA 420

  Fly   444 -RDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPV 507
             ..|:....:|.||:|.::.:|::|:||:|.|::..|.|:..:....:     |.|::||.....
  Rat   421 WNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDII-----AYGVLQNSLKTD 480

  Fly   508 YCLDNMGKSTEEAVGMFSC---------------------------ADNRTHPQPN---QFWELS 542
            .|.| .|..||....::.|                           .|||.....|   :..|.|
  Rat   481 LCFD-QGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGVLSPTIDDDDNRCLVDVNSRPRLIECS 544

  Fly   543 IFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRCLE----- 602
            ..:..|||        :|        |.:   ||||:            :....:|||||
  Rat   545 YAKAKRMK--------LH--------WQF---SQGGS------------IQNRKSKRCLELQENS 578

  Fly   603 ----GFVENGIAKVVANSCENGNDRQRW 626
                ||      ::|...|..    |.|
  Rat   579 DMEFGF------QLVLQKCSG----QHW 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	115/307 (37%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	36/173 (21%)
Galnt18	NP_001073353.1	pp-GalNAc-T	157..458	CDD:133004	115/307 (37%)
		beta-trefoil_Ricin_GALNT18	461..602	CDD:467353	36/183 (20%)