Protein Alignment Pgant4 and Galnt2

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001099666.2
• Gene: Galnt2 / 292090
• RGDID: 1310692
• Length: 570
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 179/554 - (32%)
• Similarity: 286/554 - (51%)
• Gaps: 52/554 - (9%)

  Fly    99 GERKDWHDYAAM-EADRKRSGFGEHGVAV------KIENPDEKQ----------LEKEHYEMNGF 146
            |.:.||:|..:: :.|...|...|...::      |:..||..|          ..::.|..|.|
  Rat    39 GRKGDWNDIDSIKKKDLHHSRGDEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKF 103

  Fly   147 NGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLK 211
            |.:.||::.::||:||.|.:.|:.:::...||..||:..|.||..:.|||::.||:.|:||.|:|
  Rat   104 NQVESDKLRMDRSIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKRSPPHLIK 168

  Fly   212 QIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIE 276
            :|:||||.|     ..|.|..:.... ..|.::||..|:||:.:|:.||..|..:|:.|.|||.|
  Rat   169 EIILVDDYS-----NDPEDGALLGKI-EKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCE 227

  Fly   277 VNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDALD 341
            .|..||.||:|.:|.:......|::|.|:.::|.|...:.| .:|||||.:::|...:.||....
  Rat   228 CNERWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASAD-LKGGFDWNLVFKWDYMTPEQRRS 291

  Fly   342 KS----MPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRV 402
            :.    .|.::|::.||||.::..:|.:||.||..:|:||||..|:||::|.|||.|..:|||||
  Rat   292 RQGNPVAPIKTPMIAGGLFVMDKLYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRV 356

  Fly   403 AHIFRGPMKPRGNPRGHNFV-AKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRER 466
            .|:|| ...|...|.|...| |:|.:|.|||||||:|.:.|...|.. .|:..|::..:..:|::
  Rat   357 GHVFR-KQHPYTFPGGSGTVFARNTRRAAEVWMDEFKHFYYAAVPSA-RNVPYGNIQSRLELRKK 419

  Fly   467 LKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKSTEEAVGMFSCADNRT 531
            |.||.|.|::..|.|:..|.    :....|.|.:|...|   |||.:|...:..||::.|    .
  Rat   420 LGCKPFKWYLDNVYPELRVP----DHQDIAFGALQQGTN---CLDTLGHFADGVVGIYEC----H 473

  Fly   532 HPQPNQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGEN 596
            :...||.|.|:  ::..:|..| :||.|.:..|.:.:.:..|......|.|.......:|.|..:
  Rat   474 NAGGNQEWALT--KEKSVKHMD-LCLTVVDRSPGSLIRLQGCRENDSRQKWEQIEGNSKLRHVGS 535

  Fly   597 NKRCLEGFV--ENGIAKVVANSCENGNDRQRWEF 628
            | .||:...  ..|::..|.....:    |:|:|
  Rat   536 N-LCLDSRTAKSGGLSVEVCGPALS----QQWKF 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	117/303 (39%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	34/138 (25%)
Galnt2	NP_001099666.2	pp-GalNAc-T	138..433	CDD:133004	117/303 (39%)
		beta-trefoil_Ricin_GALNT2	445..564	CDD:467312	33/133 (25%)