DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant4 and Galnt2

DIOPT Version :9

Sequence 1:	NP_001137779.1	Gene:	Pgant4 / 261610	FlyBaseID:	FBgn0051956	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	XP_038953584.1	Gene:	Galnt2 / 292090	RGDID:	1310692	Length:	570	Species:	Rattus norvegicus

Alignment Length:	554	Identity:	179/554 - (32%)
Similarity:	286/554 - (51%)	Gaps:	52/554 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 GERKDWHDYAAM-EADRKRSGFGEHGVAV------KIENPDEKQ----------LEKEHYEMNGF 146
            |.:.||:|..:: :.|...|...|...::      |:..||..|          ..::.|..|.|
  Rat    39 GRKGDWNDIDSIKKKDLHHSRGDEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKF 103

  Fly   147 NGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLK 211
            |.:.||::.::||:||.|.:.|:.:::...||..||:..|.||..:.|||::.||:.|:||.|:|
  Rat   104 NQVESDKLRMDRSIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKRSPPHLIK 168

  Fly   212 QIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIE 276
            :|:||||.|     ..|.|..:.... ..|.::||..|:||:.:|:.||..|..:|:.|.|||.|
  Rat   169 EIILVDDYS-----NDPEDGALLGKI-EKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCE 227

  Fly   277 VNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDALD 341
            .|..||.||:|.:|.:......|::|.|:.::|.|...:.| .:|||||.:::|...:.||....
  Rat   228 CNERWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASAD-LKGGFDWNLVFKWDYMTPEQRRS 291

  Fly   342 KS----MPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRV 402
            :.    .|.::|::.||||.::..:|.:||.||..:|:||||..|:||::|.|||.|..:|||||
  Rat   292 RQGNPVAPIKTPMIAGGLFVMDKLYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRV 356

  Fly   403 AHIFRGPMKPRGNPRGHNFV-AKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRER 466
            .|:|| ...|...|.|...| |:|.:|.|||||||:|.:.|...|.. .|:..|::..:..:|::
  Rat   357 GHVFR-KQHPYTFPGGSGTVFARNTRRAAEVWMDEFKHFYYAAVPSA-RNVPYGNIQSRLELRKK 419

  Fly   467 LKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKSTEEAVGMFSCADNRT 531
            |.||.|.|::..|.|:..|.    :....|.|.:|...|   |||.:|...:..||::.|    .
  Rat   420 LGCKPFKWYLDNVYPELRVP----DHQDIAFGALQQGTN---CLDTLGHFADGVVGIYEC----H 473

  Fly   532 HPQPNQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGEN 596
            :...||.|.|:  ::..:|..| :||.|.:..|.:.:.:..|......|.|.......:|.|..:
  Rat   474 NAGGNQEWALT--KEKSVKHMD-LCLTVVDRSPGSLIRLQGCRENDSRQKWEQIEGNSKLRHVGS 535

  Fly   597 NKRCLEGFV--ENGIAKVVANSCENGNDRQRWEF 628
            | .||:...  ..|::..|.....:    |:|:|
  Rat   536 N-LCLDSRTAKSGGLSVEVCGPALS----QQWKF 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	90/237 (38%)
		pp-GalNAc-T	181..480	CDD:133004	117/303 (39%)
		Ricin_B_lectin	496..626	CDD:279046	32/131 (24%)
		RICIN	498..628	CDD:238092	32/131 (24%)
Galnt2	XP_038953584.1	pp-GalNAc-T	138..433	CDD:133004	117/303 (39%)
Galnt2	XP_038953584.1	Ricin_B_lectin	445..562	CDD:395527	32/131 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810