Protein Alignment Pgant4 and Galntl6

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_017168336.2
• Gene: Galntl6 / 270049
• MGIID: 1913581
• Length: 695
• Species: Mus musculus
• Alignment Length: 658
• Identity: 261/658 - (39%)
• Similarity: 361/658 - (54%)
• Gaps: 91/658 - (13%)

  Fly     5 KRYVKRLLRKVVLLLVVIVTVSLV--TTLVVERRMKNAAELTEQLDPNGDPITPVFRAANIHPTR 67
            ||..||.|:..:|..|.::.:..:  .:|..::.:..:||..|.
Mouse    96 KRKQKRFLQMTLLFTVALIFLPNIGLWSLYKDKHLVKSAEPAEH--------------------- 139

  Fly    68 KAPRPPFQDRNSVVDIPRSDKLQGFRLPEPKGE---------RKDWHDYAAMEADRKRSGFGEHG 123
                                  |.|.|....|:         |||||||.:::.|..|||.||||
Mouse   140 ----------------------QTFPLGLGDGQFYSWTDGLRRKDWHDYESIQRDALRSGKGEHG 182

  Fly   124 VAVKIENPDEKQLEKEHYEMNGFNGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFN 188
            ....:...|.   :...|..||||..:|:.|::.||:||:|...||.:.||.:|||.|:|..|.|
Mouse   183 KPYPLTEEDR---DDSAYRENGFNIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHN 244

  Fly   189 EHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLI 253
            |.:.:|||:|:|:|||||..|:.:|:||||.|:.:.||..|:||:.:.  ..|.|||..:|:|||
Mouse   245 EGWTSLLRTIHSIINRTPESLIAEIILVDDFSDREHLKDKLEDYMARF--SKVRIVRTKKREGLI 307

  Fly   254 GARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDG 318
            ..|:.||.||.|:|:.|.|||.|||.||||||:..||:|.|...|||:|.|.|..|.|.:...|.
Mouse   308 RTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDA 372

  Fly   319 ARGGFDWKMLYKQLPVLPE-DALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYE 382
            .||.|||:|.||::|:.|| ...|.|.|:.||||.|||||::..:||:|||||..|:||||||||
Mouse   373 MRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYE 437

  Fly   383 LSFKIWMCGGMLLDVPCSRVAHIFRG--PMK-PRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKR 444
            :|||:|||||.:.|||||||.||:|.  |.| |.|..     :|:|.|||||.||||:.:|:|:|
Mouse   438 ISFKVWMCGGEMFDVPCSRVGHIYRKYVPYKVPSGTS-----LARNLKRVAETWMDEFAEYIYQR 497

  Fly   445 DPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYC 509
            .|: |.:|..||::.|:.:|:|||||.|.|||..||.|....:|||||...|.|.|::||..: |
Mouse   498 RPE-YRHLSTGDISAQKELRKRLKCKDFKWFMAAVAWDVPKYYPPVEPLPAAWGEIRSVAANL-C 560

  Fly   510 LDNMGKSTEEAVGMFSC---ADNRT--HPQPNQF-WELSI--FRDLRMKGFDSVCLDV--HEGPP 564
            :|:...:|...:.:..|   ...||  |.|...| |...|  ...|..:.|   |||.  |..|
Mouse   561 VDSKHGATGTELRLDVCVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKF---CLDAISHSSP- 621

  Fly   565 NATVWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRCLEGFVENGIAKVVANSCENGNDRQRWEFG 629
               |.::.||...|||.|.| |:.:.|.|..:|. |::  ......|:....|:..::.|:|.|.
Mouse   622 ---VTLYDCHGMKGNQLWGY-REDRTLFHPVSNS-CMD--CNPSEKKIFMARCDPLSETQQWIFE 679

  Fly   630 FVNHTMLD 637
            .:|.|:|:
Mouse   680 HINMTVLE 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	159/302 (53%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	40/145 (28%)
Galntl6	XP_017168336.2	pp-GalNAc-T	237..532	CDD:133004	159/302 (53%)
		beta-trefoil_Ricin_GALNTL6	543..688	CDD:467355	46/157 (29%)