Protein Alignment Pgant4 and GALNT1

DIOPT Version :9

• Sequence 1: NP_001137779.1
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001371367.1
• Gene: GALNT1 / 2589
• HGNCID: 4123
• Length: 559
• Species: Homo sapiens
• Alignment Length: 553
• Identity: 216/553 - (39%)
• Similarity: 318/553 - (57%)
• Gaps: 55/553 - (9%)

  Fly    83 IPRSDKLQGFRLPEPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEHYEMNGFN 147
            :|..|.|:..:.|         |:           |.||.|..|.|...|:::: ||.:::|.||
Human    42 LPAGDVLEPVQKP---------HE-----------GPGEMGKPVVIPKEDQEKM-KEMFKINQFN 85

  Fly   148 GLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQ 212
            .:.|:.|::|||:||:|||.|||:.|...||..||:.:|.||.::||||:::|||||:|..::::
Human    86 LMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEE 150

  Fly   213 IVLVDDGSEWDVLKQPLDDYVQQ-HFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIE 276
            ||||||.||.|.||:||:.||:: ..|  |.::|..:|.|||.||:.||.|:.|||:.|.|:|.|
Human   151 IVLVDDASERDFLKRPLESYVKKLKVP--VHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCE 213

  Fly   277 VNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDAL- 340
            ....||.||:..|..:.:...||::|.||.:.|.|.:|: |...|||:||:.::..|| |:..:
Human   214 CTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGS-DMTYGGFNWKLNFRWYPV-PQREMD 276

  Fly   341 ----DKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSR 401
                |:::|.|:|.|.||||:|:.|:|.::|.||..:||||||..|:||:||.|||.|..|.||.
Human   277 RRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSH 341

  Fly   402 VAHIFRGPMKPRGNPRG-HNFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRE 465
            |.|:|| ...|...|.| ...:.||::|:|||||||:|.:.|...|.. ..:|.||::.:.|:|.
Human   342 VGHVFR-KATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGV-TKVDYGDISSRVGLRH 404

  Fly   466 RLKCKSFHWFMTEVAPDFLVKFPPVEPPSY-AAGIIQNVANPVYCLDNMGKSTEEAVGMFSCADN 529
            :|:||.|.|::..:.||..:      |..| :.|.|:||... .|||||.:...|.||:|:|
Human   405 KLQCKPFSWYLENIYPDSQI------PRHYFSLGEIRNVETN-QCLDNMARKENEKVGIFNC--- 459

  Fly   530 RTHPQ-PNQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVH 593
              |.. .||.:..:..:::|.   |.:||||.:  .|..|.|..||...|||.|.||.....|.|
Human   460 --HGMGGNQVFSYTANKEIRT---DDLCLDVSK--LNGPVTMLKCHHLKGNQLWEYDPVKLTLQH 517

  Fly   594 GENNKRCLEGFVENGIAKVVANSCENGNDRQRW 626
             .|:.:||:...|..........| ||:..|:|
Human   518 -VNSNQCLDKATEEDSQVPSIRDC-NGSRSQQW 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	109/239 (46%)
		pp-GalNAc-T	181..480	CDD:133004	134/305 (44%)
		Ricin_B_lectin	496..626	CDD:279046	44/130 (34%)
		RICIN	498..628	CDD:238092	45/130 (35%)
GALNT1	NP_001371367.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..65		8/39 (21%)
		Catalytic subdomain A	115..225		55/111 (50%)
		pp-GalNAc-T	119..419	CDD:133004	134/305 (44%)
		Catalytic subdomain B	285..347		34/61 (56%)
		Ricin_B_lectin	432..548	CDD:395527	44/128 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810