Protein Alignment Pgant4 and gly-5

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001379253.1
• Gene: gly-5 / 176736
• WormBaseID: WBGene00001630
• Length: 626
• Species: Caenorhabditis elegans
• Alignment Length: 650
• Identity: 239/650 - (36%)
• Similarity: 343/650 - (52%)
• Gaps: 80/650 - (12%)

  Fly    13 RKVVLLLVVIVTVSLVTTLVVERRMKNAAELTEQLDPNGDPITPVFRAANIHPTRKAPR------ 71
            :|.:|.::::|.|..:.:|:......|.   :.|:..|.| :......||.||  ||.:
 Worm     6 KKAILKVLLLVPVFWICSLIFFAATSND---SSQIGSNND-LANKIAEANFHP--KAAKQDVIQG 64

  Fly    72 --PPFQ-----DRNSVVDIPRSDKLQGFRLPEPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIE 129
              ||.:     :.|.|    ..::..|..|.:|| ...|.:|....:.|..::  ||.|.||.::
 Worm    65 FGPPIEPEPVVENNKV----EEEEQPGGNLAKPK-FMVDPNDPIYKKGDAAQA--GELGKAVVVD 122

  Fly   130 NPDEKQLEKEHYEM----NGFNGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEH 190
            .......||..|:.    |.||...||.|||:|::|......|||.||...||..|||..|.||.
 Worm   123 KTKLSTEEKAKYDKGMLNNAFNQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEA 187

  Fly   191 FNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGA 255
            ::.|||:::||:.|||..||:::|||||.|:.|..|:||::|:.| |...|.|:|..:|:|||.|
 Worm   188 WSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYMSQ-FGGKVKILRMEKREGLIRA 251

  Fly   256 RIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTIS------HEDFSYFSG 314
            |:.||.||.|:|:.:.|||.|....|:.||::.|..:|....||::|.|.      |...:||:
 Worm   252 RLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFT- 315

  Fly   315 NKDGARGGFDWKMLYKQLPVLPEDALDKSM---PYRSPVMMGGLFAINTDFFWDLGGYDDQLDIW 376
                :.|||||.:.:....:...|..:::.   |.|||.|.||||:|:..:|..||.||...|||
 Worm   316 ----SVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIW 376

  Fly   377 GGEQYELSFKIWMCGGMLLDVPCSRVAHIF--RGPMKPRGNPRGHNFVAKNHKRVAEVWMDEYKQ 439
            |||..|||||||||||.|..||||.|.|:|  |.|.|.|   .|.|.:.:|..|:||||:|:||.
 Worm   377 GGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWR---TGVNVLKRNSIRLAEVWLDDYKT 438

  Fly   440 YVYKRDPKTYDNL--DAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQN 502
            |.|:|    .:|.  |.||::.::.:||.|.||||.|::..:.|:.   |.|.|  |.|.|.::|
 Worm   439 YYYER----INNQLGDFGDISSRKKLREDLGCKSFKWYLDNIYPEL---FVPGE--SVAKGEVRN 494

  Fly   503 VA-NPVYCLDNMGKSTEE--AVGMFSCADNRTHPQ-PNQFWELSIFRDLRMKGFDSVCLDVHEGP 563
            .| .|..|||.|....|:  .||.:.|     |.| .||:|.||...::|.   |..|:|.
 Worm   495 SAVQPARCLDCMVGRHEKNRPVGTYQC-----HGQGGNQYWMLSKDGEIRR---DESCVDY---- 547

  Fly   564 PNATVWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRCLEGFVENGIAKVVANSCENGNDRQRWEF 628
            ..:.|.::.||...|||.|.|:..|.||.|..:.| || |..::| ||:...:|:..:..|.|:|
 Worm   548 AGSDVMVFPCHGMKGNQEWRYNHDTGRLQHAVSQK-CL-GMTKDG-AKLEMVACQYDDPYQHWKF 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	136/311 (44%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	47/139 (34%)
gly-5	NP_001379253.1	pp-GalNAc-T	178..477	CDD:133004	136/311 (44%)
		beta-trefoil_Ricin_Pgant9-like	485..610	CDD:467340	48/141 (34%)