Protein Alignment Pgant4 and gly-3

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_498722.1
• Gene: gly-3 / 176112
• WormBaseID: WBGene00001628
• Length: 612
• Species: Caenorhabditis elegans
• Alignment Length: 638
• Identity: 212/638 - (33%)
• Similarity: 332/638 - (52%)
• Gaps: 77/638 - (12%)

  Fly    11 LLRKVVLLLVVIVTVSLVTTLVVERRMKNAAELTEQL--------DPNGDPITPVFRAANIHPTR 67
            |:..|:|...:..:.|.......:.|:.|.|...|.|        ||:..||.|..:...::|
 Worm    24 LIDVVILFYYLDPSTSQQQPFPEDNRILNRARRIEPLPPAAQHDSDPDAHPIQPEKQEKQVYP-- 86

  Fly    68 KAPRPPFQDRNSVVDIPRSDKLQGFRLPEPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIENPD 132
                         ||...:::|:  :|.|.:.....:|            |.|..||.|.   .|
 Worm    87 -------------VDKETANQLR--KLMETQAFGPGYH------------GQGGTGVTVP---ED 121

  Fly   133 EKQLEKEHYEMNGFNGLISDRISVNRSVPDLRLEACKT---RKYLAKLPNISVIFIFFNEHFNTL 194
            :|.::::.:..|.||.:.|:.|||||::||.|.:||:|   ....|.:|..|:|.:|.||.:.||
 Worm   122 KKTIKEKRFLENQFNVVASEMISVNRTLPDYRSDACRTSGNNLKTAGMPKTSIIIVFHNEAWTTL 186

  Fly   195 LRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAG 259
            ||:::|||||:|..||::|:||||.|:.|.|.:|||.|::. ||..:.:|....|.|||.||:.|
 Worm   187 LRTLHSVINRSPRHLLEEIILVDDKSDRDYLVKPLDSYIKM-FPIPIHLVHLENRSGLIRARLTG 250

  Fly   260 AKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFD 324
            :::|.|::::|.|:|:||...||.||:..:|.:.|....|::|.||.:.|.|.:.: :...|||:
 Worm   251 SEMAKGKILLFLDAHVEVTDGWLEPLVSRVAEDRKRVVAPIIDVISDDTFEYVTAS-ETTWGGFN 314

  Fly   325 WKMLYKQLPVLPEDAL-----DKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELS 384
            |.:.::...| |:..|     |:|||.::|.:.||||||:..||:|:|.||:.:.:||||..|:|
 Worm   315 WHLNFRWYAV-PKRELNRRGSDRSMPIQTPTIAGGLFAIDKQFFYDIGSYDEGMQVWGGENLEIS 378

  Fly   385 FKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRG-HNFVAKNHKRVAEVWMDEYKQYVYKRDPKT 448
            |::|||||.|...|||||.|:|| ...|...|.| ...:..|..|.|||||||||.:.||..|..
 Worm   379 FRVWMCGGSLEIHPCSRVGHVFR-KQTPYTFPGGTAKVIHHNAARTAEVWMDEYKAFFYKMVPAA 442

  Fly   449 YDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNM 513
             .|::|||::.::.:||.|:||||.|::..:.|:     .|:.....:.|.|.|.... .|:|..
 Worm   443 -RNVEAGDVSERKKLRETLQCKSFKWYLENIYPE-----APLPADFRSLGAIVNRFTE-KCVDTN 500

  Fly   514 GKSTEEAVGMFSCADNRTH-PQPNQFWELSIFRDLRMKGFDSVCLD---VHEGPPNATVWMWSCH 574
            ||...:|.|:.:|     | ...||.|.|:...::|.   |.:||.   |::......:...|..
 Worm   501 GKKDGQAPGIQAC-----HGAGGNQAWSLTGKGEIRS---DDLCLSSGHVYQIGSELKLERCSVS 557

  Fly   575 SQGGNQFWYYDRQTQRLVHGENNKRCLEGFVENGIAKVVANSCENGNDRQRWE 627
            .......:.:|.|...|:|.:..| |:.|..:    :|..:.|..|...|.|:
 Worm   558 KINVKHVFVFDDQAGTLLHKKTGK-CVTGADQ----RVTLDECGLGRKDQMWQ 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	132/304 (43%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	33/139 (24%)
gly-3	NP_498722.1	pp-GalNAc-T	173..473	CDD:133004	132/304 (43%)
		beta-trefoil_Ricin_GALNT1-like	481..608	CDD:467311	33/139 (24%)