Protein Alignment Pgant4 and Pgant1

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_308833.5
• Gene: Pgant1 / 1270158
• VectorBaseID: AGAMI1_002243
• Length: 622
• Species: Anopheles gambiae
• Alignment Length: 650
• Identity: 212/650 - (32%)
• Similarity: 305/650 - (46%)
• Gaps: 106/650 - (16%)

  Fly     8 VKRLLRKVVLLLVVIVTVSLVTTLVVERRMKN--------AAELTEQLDPNGDPITPVFRAANIH 64
            ::|.|...||||       ||..|.|....||        .:...||..|.......|.|...:.
Mosquito     9 IRRNLYTRVLLL-------LVLGLFVLFYFKNLNGSPNSLGSPALEQAKPLAQLGLDVNRLELLA 66

  Fly    65 PTRKAPRPPFQDRNSVVDIPRSDKLQGFRLPEPKG----ERKDWHDYAAMEADRKRSGFGEHGVA 125
            ....|...|....|.:..:|            |.|    ||....|.|     ::|.|.|.:|..
Mosquito    67 AAEAAAGGPLNKGNLLPALP------------PSGDALFERLVLADLA-----KQRPGLGNNGEG 114

  Fly   126 VKIENPDEKQLEKEHYEMNGFNGLISDRISVNRSVPDLRLEACKTRKY-LAKLPNISVIFIFFNE 189
            |::.. |.|::.::.......|..:|:.:|.||:.||.|..|||.:.| |..||:.:||.||:||
Mosquito   115 VELTG-DAKEIGEKQLATIALNEELSEHLSYNRTPPDGRHPACKRKHYDLTGLPSTNVIIIFYNE 178

  Fly   190 HFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIG 254
            .::.|||:::||:|.....||::|:||||||....||..||.||:...|..|.::|..:|.|||.
Mosquito   179 PYSVLLRTVHSVLNTADGRLLREIILVDDGSTNVELKGKLDYYVRTRLPAKVKVLRQRQRVGLIR 243

  Fly   255 ARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGN--KD 317
            ||:|||::|...|:||.|:|.|....||.||:|.|..:|.....|::|.|..::| |:|.|  .|
Mosquito   244 ARLAGARLAKADVLVFLDAHCECMVQWLEPLLERIKESPTSVLVPIIDVIEAKNF-YYSTNDYND 307

  Fly   318 GARGGFDW-------KMLYKQLPVLPEDALDKSM---PYRSPVMMGGLFAINTDFFWDLGGYDDQ 372
            ...|||.|       .:..::......:..:|.:   |..||.|.||||||..|:|||:|.||:|
Mosquito   308 FQIGGFTWDGHFDWHDVTKRERERQKRECAEKDLEICPTYSPTMAGGLFAIARDYFWDIGSYDEQ 372

  Fly   373 LDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGHNFVAKNHKRVAEVWMDEY 437
            :|.||||..|:||::|.|||.|..:||||:.|||| ...|...|...:....|..|:|.||||:|
Mosquito   373 MDGWGGENLEMSFRVWQCGGTLETIPCSRIGHIFR-DFHPYSFPNNRDTHGINTVRMAIVWMDDY 436

  Fly   438 KQYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQN 502
            .:.:|...|...|:.:.||:|.::.:||:|.||||.|:|..|.|:   ||.|..... |.|.:.:
Mosquito   437 VELLYLNRPDLKDHPELGDVTHRKVLREKLHCKSFDWYMKNVYPE---KFIPTRNVR-AFGRLAS 497

  Fly   503 VANPVYCLD----------NMG-----------------------------------KSTEEAVG 522
            .|:.: |||          |:|                                   ||..:.|.
Mosquito   498 QADNL-CLDTLQQNADKPWNLGIYTCFKPEVSASQLFSLTKRNVLRNERSCATVQASKSESKFVV 561

  Fly   523 MFSCADNRTHPQPNQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQ 587
            |..|.|:.   ..:..||.:..|.||.|. ..:|||..:....:.|.:.:||.....|.|.:..:
Mosquito   562 MIPCIDDE---DIDDTWEFTEHRQLRHKQ-SGLCLDSSDLSTKSYVHVATCHPGIKTQKWEFQHE 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	130/310 (42%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	28/139 (20%)
Pgant1	XP_308833.5	None