Protein Alignment Pgant4 and galnt6.2

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_031753046.1
• Gene: galnt6.2 / 100486937
• XenbaseID: XB-GENE-1000674
• Length: 623
• Species: Xenopus tropicalis
• Alignment Length: 677
• Identity: 203/677 - (29%)
• Similarity: 310/677 - (45%)
• Gaps: 149/677 - (22%)

  Fly     4 KKRYVKRLLRKVVLLLVVIVTV------------SLVTTLVVER---------RMKNAAELTEQL 47
            ::.|....|..|.::.|:.|.:            ..:..:||.:         .|||..:...:|
 Frog     5 RRNYGPLKLAMVGMVFVIFVFIMHKDIGNGAKDDPWIKNIVVRKDQMINMMRGAMKNLKDSIPKL 69

  Fly    48 DPNG--DPITPVFRAANIHPTRKAP--------RPPFQDRNSVVDIPRSDKLQGFRLPEPKGERK 102
            ....  ..:.||....:..|....|        ||| ||.||    |.:|         .||..|
 Frog    70 QIMAPVQEVRPVEEKKSCLPGYYTPAELKPFMERPP-QDPNS----PGAD---------GKGFIK 120

  Fly   103 D-WHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEHYEMNGFNGLISDRISVNRSV-PDLRL 165
            : |.:   .|.:.|..||.:|                      .||...|||||::|:: ||.|.
 Frog   121 NIWTE---EEVEEKEKGFDKH----------------------CFNAFASDRISLHRALGPDTRP 160

  Fly   166 EACKTRKY--LAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQP 228
            ..|..:|:  ...||..|:|.:|.||.::||||::|||:..:|..|||:|:||||.||.:.||:.
 Frog   161 LECIEQKFKRCPSLPTTSIIIVFHNEAWSTLLRTVYSVLYTSPAILLKEIILVDDASEDEYLKEK 225

  Fly   229 LDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINP 293
            |||||:.  ..:|.|.|..||:|||.||:.||.:|.|:|:.|.|:|.|..:.||.||:..:|.:.
 Frog   226 LDDYVKA--LQIVKIARQKERKGLITARLLGASIATGEVLTFLDAHCECFHGWLEPLLSRVAEDH 288

  Fly   294 KISTCPMVDTISHEDFSY---FSGNKDGARGGFDWKMLY--KQLPVLPE-DALDKSMPYRSPVMM 352
            .....|.:..|::..|.:   ....|..:||.|||.:.:  :.:|...| ...|::.|.::|...
 Frog   289 TAVVSPDITAINYNTFEFGKPVQQGKMNSRGNFDWSLAFNWEAIPAADEKQRKDETYPIKTPTFA 353

  Fly   353 GGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPR 417
            ||||:|:..:|..:|.||::::|||||..|:||::|.|||.|..:|||.|.|:|| ...|...|:
 Frog   354 GGLFSISKAYFEHIGSYDEEMEIWGGENVEMSFRVWQCGGKLEIIPCSVVGHVFR-TKSPHTFPK 417

  Fly   418 GHNFVAKNHKRVAEVWMDEYKQYVYKRD---PKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEV 479
            |...:.:|..|:||||||:||...|:|:   .|.......||::::..::..|:||:|.|::..:
 Frog   418 GTQVILRNQVRLAEVWMDDYKVLYYRRNEQAAKIAKEKSFGDISKRLKLKADLQCKNFTWYLENI 482

  Fly   480 APDFLVKFPPVEPPSYAAGIIQNVANPVYCLDNMGKSTEEAVGMFSCADNRTHPQPNQFWELSIF 544
            .|:.   |.|...|:| .|.|:|            :.|:.
 Frog   483 YPEM---FVPDRDPTY-YGAIKN------------EGTQN------------------------- 506

  Fly   545 RDLRMKGFDSVCLDVHEGPPNATVW--MWSCHSQGGNQFWYYDRQTQRLVHGENNKRCLEGFVEN 607
                       |:||.|.....:..  |:.||..||||::.|... :.|.|....:.||....|.
 Frog   507 -----------CIDVGENNNYGSQLPIMYPCHGMGGNQYFEYSTH-KELRHNLKTQLCLCSKYEP 559

  Fly   608 GIAKVV------ANSCENGNDRQRWEF 628
            |..|:|      .|:...||  :.|||
 Frog   560 GPVKLVDCQYKGQNTTVPGN--EEWEF 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	120/307 (39%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	32/144 (22%)
galnt6.2	XP_031753046.1	pp-GalNAc-T	178..483	CDD:133004	120/307 (39%)
		beta-trefoil_Ricin-like	493..623	CDD:483949	32/144 (22%)