Protein Alignment Pgant4 and Galnt6

DIOPT Version :10

• Sequence 1: NP_722910.2
• Gene: Pgant4 / 261610
• FlyBaseID: FBgn0051956
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: NP_001165534.1
• Gene: Galnt6 / 100361647
• RGDID: 2319726
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 624
• Identity: 199/624 - (31%)
• Similarity: 307/624 - (49%)
• Gaps: 130/624 - (20%)

  Fly     2 AIKKRYVKRLL-RKVVLLLVVIVTVSLVTTLVVERRMKNAAELTEQLDPNGDPITPVFRAANIHP 65
            |::|.::|.|. :|..:|.:::..|:.:..::.:.:::........:..|...:...:..|.:.|
  Rat    37 AMEKPWLKSLAGQKDHVLDLMLGAVNNIRDVMPKLQIRAPEPQQNPVSTNHSCLPGFYTPAELRP 101

  Fly    66 TRKAPRPPFQDRNSVVDIPRSDKLQGFRLPEPKGERKDWHDYAAMEADRKRSGFGEHGVAVKIEN 130
            ..:  ||| ||.||    |.:|. :.|       ::|:|   ..:|...|..|:.:|
  Rat   102 FWE--RPP-QDPNS----PGADG-KAF-------QKKEW---TLLETQEKDEGYKKH-------- 140

  Fly   131 PDEKQLEKEHYEMNGFNGLISDRISVNRSV-PDLRLEACKTRKY--LAKLPNISVIFIFFNEHFN 192
                          .||...|||||:.||: ||.|...|..:|:  ...||..||:.:|.||.::
  Rat   141 --------------CFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPLPTTSVVIVFHNEAWS 191

  Fly   193 TLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARI 257
            ||||::|||::.:|..|||:|:||||.|..:.||:.|:.||||  ..:|.:||..||:|||.||:
  Rat   192 TLLRTVYSVLHTSPAILLKEIILVDDASTDEHLKEKLERYVQQ--LQIVRVVRQQERKGLITARL 254

  Fly   258 AGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDG---A 319
            .||.||..:|:.|.|:|.|..:.||.||:..||.:......|.:.||....|.:....:.|   :
  Rat   255 LGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAVVSPDIVTIDLNTFQFSKPMRRGKAHS 319

  Fly   320 RGGFDWKMLYKQLPVLPED----ALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQ 380
            ||.|||.:.: ...:|||.    ..|::.|.:||...||||:|:..:|..:|.||:|::|||||.
  Rat   320 RGNFDWSLTF-GWEMLPEHEKQRRKDETYPIKSPTFAGGLFSISKAYFEHIGTYDNQMEIWGGEN 383

  Fly   381 YELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKRD 445
            .|:||::|.|||.|..:|||.|.|:|| ...|...|:|.:.:|:|..|:||||||:||:..|:|
  Rat   384 VEMSFRVWQCGGQLEIIPCSVVGHVFR-TKSPHTFPKGTSVIARNQVRLAEVWMDDYKKIFYRR- 446

  Fly   446 PKTYDNLDA---------GDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQ 501
                 ||.|         ||::.:..:||:|.|.:|.|::..|.|:..|  |.:.|.  .:|.|:
  Rat   447 -----NLQAAKMAKENNFGDVSERLRLREQLHCHNFSWYLHNVYPEMFV--PDLNPT--FSGAIK 502

  Fly   502 NVANPVYCLDNMGKSTEEAVGMFSCADNRTHPQPNQFWELSIFRDLRMKGFDSVCLDVHE----G 562
            |:..                                                |.||||.|    |
  Rat   503 NLGT------------------------------------------------SQCLDVGENNRGG 519

  Fly   563 PPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRCL 601
            .|   :.|:.||:.||||::.|..| :.|.|....:.||
  Rat   520 KP---LIMYVCHNLGGNQYFEYTSQ-RDLRHNIGKQLCL 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant4	NP_722910.2	pp-GalNAc-T	181..480	CDD:133004	128/314 (41%)
		beta-trefoil_Ricin_Pgant9-like	493..629	CDD:467340	24/113 (21%)
Galnt6	NP_001165534.1	pp-GalNAc-T	180..485	CDD:133004	128/314 (41%)
		beta-trefoil_Ricin-like	495..622	CDD:483949	25/114 (22%)