DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32445 and GAL10

DIOPT Version :9

Sequence 1:	NP_730671.1	Gene:	CG32445 / 261603	FlyBaseID:	FBgn0052445	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_009575.1	Gene:	GAL10 / 852307	SGDID:	S000000223	Length:	699	Species:	Saccharomyces cerevisiae

Alignment Length:	341	Identity:	104/341 - (30%)
Similarity:	165/341 - (48%)	Gaps:	54/341 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 MGAIIQSLKVPDFNGKLEDVCLGYDDVAGYYRNQQYFFGATIGRVANRTAHGRFKLCGK--EVSV 103
            :||.|..|||   ||  :.|.|||::..||......:.||||||.|||.:.|:|.||.|  :::|
Yeast   391 LGASIVDLKV---NG--QSVVLGYENEEGYLNPDSAYIGATIGRYANRISKGKFSLCNKDYQLTV 450

  Fly   104 SRNLRDRHHQNGGF--VGFDSVIWDVVGVHKDGVTLQHISPDGHEG--YPGELTTNINFSLNETG 164
            :..:...|...|.|  ..|...|  :....||..|.:::..|..:.  :||:|...|.:::| ..
Yeast   451 NNGVNANHSSIGSFHRKRFLGPI--IQNPSKDVFTAEYMLIDNEKDTEFPGDLLVTIQYTVN-VA 512

  Fly   165 CFGMRIEARTKAT----TAVNISNHSFFNL-AGHGAGRDTLYQHMLMIKAQKIVDVDQELLPTGK 224
            ...:.:..:.|.|    |.:|::|||:||| ..:|   ||:....:|::::|.||||:.::|||.
Yeast   513 QKSLEMVYKGKLTAGEATPINLTNHSYFNLNKPYG---DTIEGTEIMVRSKKSVDVDKNMIPTGN 574

  Fly   225 LMRVRTTPYDFSSLVSLGKRLNQVSTCPLGGFDNHFCVD--IPP-------NRVQLVARVVHPCS 280
            ::......::.:....||.:..|...|        |.||  ..|       |.:.|:.:..||.|
Yeast   575 IVDREIATFNSTKPTVLGPKNPQFDCC--------FVVDENAKPSQINTLNNELTLIVKAFHPDS 631

  Fly   281 GRFMEVHTNQPGLQFSTANHLPSEDGSDIPIAGKDGVNYVRQGAFTLETQKYPDAMNHCDFPS-V 344
            ...:||.:.:|..||.|.:.|.         ||.:    .||| |.:|..:|.||:|..::.. |
Yeast   632 NITLEVLSTEPTYQFYTGDFLS---------AGYE----ARQG-FAIEPGRYIDAINQENWKDCV 682

  Fly   345 VLNPGQLYDHQVVYRF 360
            .|..|:.|..::||||
Yeast   683 TLKNGETYGSKIVYRF 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32445	NP_730671.1	galactose_mutarotase_like	25..360	CDD:185696	102/339 (30%)
GAL10	NP_009575.1	UDP_G4E_1_SDR_e	14..349	CDD:187558
GAL10	NP_009575.1	galactose_mutarotase_like	376..698	CDD:185696	102/339 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	117	1.000	Domainoid score	I1291
eggNOG	1	0.900	-	-		E1_COG2017
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810