DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32445 and galm

DIOPT Version :9

Sequence 1:	NP_730671.1	Gene:	CG32445 / 261603	FlyBaseID:	FBgn0052445	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_001002373.1	Gene:	galm / 436646	ZFINID:	ZDB-GENE-040718-66	Length:	342	Species:	Danio rerio

Alignment Length:	362	Identity:	148/362 - (40%)
Similarity:	214/362 - (59%)	Gaps:	25/362 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVRVIEDMFGIAVNPMTQKTDRVRRFTLVTERGMSVSILTMGAIIQSLKVPDFNGKLEDVCLGYD 65
            |..|.::.||.|:.|       |.|: ::....:||.|:::|.:|:|:|..|.:|:..|:.||:|
Zfish     1 MTEVHKEEFGTALGP-------VERW-ILRSASVSVEIISLGCVIKSIKTADRSGQSADIVLGFD 57

  Fly    66 DVAGYYRNQQYFFGATIGRVANRTAHGRFKLCGKEVSVSRNLRDRHHQNGGFVGFDSVIWDVVGV 130
            |:.||:.|.:| |||.:||||||.:.|||.:..||..::.| ...:..:||..|||..:|....|
Zfish    58 DIEGYFSNPRY-FGAVVGRVANRISKGRFVIDEKEYKLAIN-NGPNALHGGLKGFDKAVWSTEAV 120

  Fly   131 HKDGVTLQHISPDGHEGYPGELTTNINFSLNETGCFGMRIEARTKATTAVNISNHSFFNLAGHGA 195
             .:||.|.|.||||.|||||.|..::.::| |.....:...|:|..||.:|::|||:|||||.|.
Zfish   121 -DNGVKLSHSSPDGDEGYPGNLKVSVTYTL-EKSTLSVLYHAQTDHTTPINLTNHSYFNLAGEGT 183

  Fly   196 GRDTLYQHMLMIKAQKIVDVDQELLPTGKLMRVRTTPYDFSSLVSLGKRLNQVSTCPLGGFDNHF 260
              ..:|.|.:.|.|:..:.||..::|||::..|..||:|....|.||.||.::|.   .|||::|
Zfish   184 --PDIYDHEVTISAESYLPVDDTVIPTGEVKPVEKTPFDLRKPVILGFRLKELSG---PGFDHNF 243

  Fly   261 CVDIP--PNRVQLVARVVHPCSGRFMEVHTNQPGLQFSTANHLPSEDGSDIPIAGKDGVNYVRQG 323
            |:.:|  |...:..||||||.:||.:||.|.|||:||.|:|.|   |||   :.||.|..|.:..
Zfish   244 CLYLPGEPPLERKCARVVHPGTGRVLEVSTTQPGVQFYTSNFL---DGS---VKGKGGAAYSKHS 302

  Fly   324 AFTLETQKYPDAMNHCDFPSVVLNPGQLYDHQVVYRF 360
            ||.||||.:|||:|...||..:|.||:.|.|...:.|
Zfish   303 AFCLETQNWPDAVNQPHFPDALLRPGETYSHTTRFTF 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32445	NP_730671.1	galactose_mutarotase_like	25..360	CDD:185696	140/336 (42%)
galm	NP_001002373.1	galactose_mutarotase_like	26..339	CDD:185696	139/327 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582910
Domainoid	1	1.000	296	1.000	Domainoid score	I1446
eggNOG	1	0.900	-	-		E1_COG2017
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2663
OMA	1	1.010	-	-		QHG62696
OrthoDB	1	1.010	-	-		D482699at33208
OrthoFinder	1	1.000	-	-		FOG0001529
OrthoInspector	1	1.000	-	-		otm24263
orthoMCL	1	0.900	-	-		OOG6_101504
Panther	1	1.100	-	-	O	PTHR10091
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1103
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.810