Protein Alignment mthl12 and adgrg11

DIOPT Version :9

• Sequence 1: NP_731791.2
• Gene: mthl12 / 261599
• FlyBaseID: FBgn0045442
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: XP_017208200.1
• Gene: adgrg11 / 563883
• ZFINID: ZDB-GENE-041210-320
• Length: 793
• Species: Danio rerio
• Alignment Length: 646
• Identity: 115/646 - (17%)
• Similarity: 201/646 - (31%)
• Gaps: 266/646 - (41%)

  Fly     4 WLK----------CFCTLIIVTIAKNSSAKIPHCKYDETINISHFKRLNDAYIYEHFEI------ 52
            |.|          |..|.:....|..:::..|.|..|.:.|:|:  ::|.      |||
Zfish   223 WTKQTTTSFNNNTCNVTCLNTKKACETASYNPSCSDDNSNNVSN--KMNT------FEINGGSAA 279

  Fly    53 ----------------PANLTGEF---DYKELMDGSKVPTEFPNLRGCIC-------------KV 85
                            ||.:|.:|   |.|.::|.....:...:|...:.             .|
Zfish   280 CIKCGNPFQPAQTITLPAEITEKFNQNDTKTVIDAGAAASAMKDLSSMLSYMGNLTVASVSMGSV 344

  Fly    86 RPCIRICCARKNILSNGECSD---------GVKNEIKLTMLDLTMQDILLTDPTLAELNMIPQYN 141
            :..:      |.|.|..|.::         ||:               |:.|||:  |...|
Zfish   345 KGIL------KKIQSESEVTETAFIYSPATGVR---------------LIDDPTV--LKNYP--- 383

  Fly   142 STELLILREQFQPCDEIVSLKRDEYTIL---------KDGSILLHTSAEILSNDQYCLYPEIYSD 197
             ..|::.:|..|.     :|.:.....|         ||.:     ::::|:|:.|.:  |:.:.
Zfish   384 -NALIVPKEAAQQ-----ALNQSSNAFLGVFRFPNMSKDAN-----NSDVLNNEVYAI--EMGTK 435

  Fly   198 FPETIRIIN------------RRCY----------------RNVMPG------------------ 216
            .......||            ..||                |.|:.|
Zfish   436 IKNLSNTINLSFNMSQSTSGTPTCYSWDGNGSKPDWTTEGCRTVVNGSGITCKCEHLTFFAVLMA 500

  Fly   217 ----------IAQLSVISVVG-----FILTLAVYL-----------SVEKLRNLLGKCLICSLFS 255
                      :..|:.|:.:|     |.|.:.:::           ||..|.||.....:.::..
Zfish   501 PPDITLRESDLTALTYITYIGCGLSMFFLGVGLFMHFLMRKAKATNSVHVLINLFLALFMLNVAF 565

  Fly   256 MFMEYFIWTMDYFRLLQSICSAAGYMKYFFSMSSYLWFSVVSFHLWELF--TSLNRHEPQYRFLI 318
            :..||.:...:     ..:|.......::..:||:.||:|.:.||....  |:..:|     :|:
Zfish   566 LTNEYVVQAQN-----SILCRVMAAFLHYCLLSSFTWFAVEALHLCLQMTKTATLKH-----YLL 620

  Fly   319 YNTFV-WCTAAIPTVVIFSMNQMWENDPGKSEWLPLVGYFGCSVKDWNSSSWFYSHIPIVILNSF 382
            ..|.. |...|....||||:.:..|::                                ::..|.
Zfish   621 KITVAGWAPPAFVVSVIFSLGKYGEDN--------------------------------IMTESR 653

  Fly   383 NVIM-FVLTAIYIWKVKKGVKSFAQHDERNTTCLEFNVQTYIQFVR-LFLIMGASWLLD-----Q 440
            ||.| :::.:...:.|..|...|.         ..|.:.|:|..|| |.::..:.|..|     .
Zfish   654 NVTMCWIVDSTVHYVVNIGYYCFV---------FTFTLGTFIVVVRWLSMLRMSKWSKDGKVKRS 709

  Fly   441 LTRLAEDSHLLLDTIVLNLT-------------------VYLNAAFGILIFVLLILKGSTF 482
            .|..::.|.:|....:|.||                   ..||:..|..:|| ..||.|||
Zfish   710 GTATSDISTMLGLCCLLGLTWGISFFSYGALRMPSYYIFTILNSLQGFFLFV-YYLKTSTF 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl12	NP_731791.2	Methuselah_N	27..209	CDD:284145	42/249 (17%)
adgrg11	XP_017208200.1	GPS	457..498	CDD:280071	5/40 (13%)
		7tm_4	511..759	CDD:304433	55/298 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900