Protein Alignment mthl12 and mthl7

DIOPT Version :9

• Sequence 1: NP_731791.2
• Gene: mthl12 / 261599
• FlyBaseID: FBgn0045442
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_648181.2
• Gene: mthl7 / 38910
• FlyBaseID: FBgn0035847
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 508
• Identity: 214/508 - (42%)
• Similarity: 321/508 - (63%)
• Gaps: 46/508 - (9%)

  Fly     4 WLKCFCTLIIVTIAKNSSAKIPHCKYDETINISHFKRLNDAYIYEHFEIPANLTGEFDYKELMDG 68
            |: .|||::::....||:|.||.|.|.:|::||:.:|.||:|:|:..||||:|||.:::::..||
  Fly     5 WV-IFCTVLLLIFTNNSNADIPGCNYYDTVDISYIERQNDSYLYDDIEIPASLTGYYEFRQFGDG 68

  Fly    69 SKVPTEFPNLRGCICKVRPCIRICCARKNILSNGECSDGVKNE-------IKLTMLDLTMQDILL 126
            |..|.| .:||.|:|.|||||||||..||.|:||:|.||:|.|       |..|.:||..:
  Fly    69 SITPIE-KHLRACVCSVRPCIRICCPAKNFLANGKCDDGLKEELARFKPYIYFTYMDLQAR---- 128

  Fly   127 TDPTLAELNMIPQYNSTELLILREQFQPCDEIVSLKRDEYTILKDGSILLHTSAEI--------- 182
                      :|   .|::.|:|::|..|||::.:....| .|::.||.:.....:
  Fly   129 ----------VP---LTDMAIIRDEFFDCDEMIYISDFNY-FLEEVSIQIFNKCGLIVWFQDGKF 179

  Fly   183 -------LSNDQYCLYPEIY-SDFPETIRIINRRCYRNVMPGIAQLSVISVVGFILTLAVYLSVE 239
                   :....||||...: ||||:::.||..||..::.||..::.:|:::.|:||:||||.::
  Fly   180 WVTVDLFMEKQDYCLYRHNFDSDFPKSMWIIRHRCTSHISPGSLEILIITMICFVLTIAVYLYIK 244

  Fly   240 KLRNLLGKCLICSLFSMFMEYFIWTMDYFRLLQSICSAAGYMKYFFSMSSYLWFSVVSFHLWELF 304
            ||||:.|||::|.:.|.|::..|..:|:..||..|||.|||..:||.|:|.||.||:|:|.|::.
  Fly   245 KLRNVTGKCIVCCIVSRFIQCLIMILDHLNLLNGICSPAGYSSHFFRMASNLWLSVISYHTWKVL 309

  Fly   305 TSLNRHEPQYRFLIYNTFVWCTAAIPTVVIFSMNQMWENDPGKSEWLPLVGYFGCSVKDWNSSSW 369
            |||||.:|.||||.||.|||.||||.|..|:.:||:|||||.|..||||||:..||||||:.|.|
  Fly   310 TSLNRVDPNYRFLRYNAFVWSTAAIMTGSIYIVNQIWENDPSKWNWLPLVGFIRCSVKDWHPSVW 374

  Fly   370 FYSHIPIVILNSFNVIMFVLTAIYIWKVKKGVKSFAQHDERNTTCLEFNVQTYIQFVRLFLIMGA 434
            .|...|.:.|::|||.||.||||||.|||.|:..|...:|....|:.|:.|||:||:||.::||.
  Fly   375 IYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYLQFLRLSIVMGL 439

  Fly   435 SWLLDQLTRLAEDSHLLLDTIVLNLTVYLNAAFGILIFVLLILKGSTFKMIME 487
            :|:.:.:...|. .|:..:.:.: ::.|.::||||::||||:||.||:.::|:
  Fly   440 TWIFNVIPYSAR-LHIFWEWVGI-ISEYFHSAFGIVLFVLLVLKRSTWTLMMD 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl12	NP_731791.2	Methuselah_N	27..209	CDD:284145	71/205 (35%)
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804	71/205 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449107
Domainoid	1	1.000	49	1.000	Domainoid score	I4416
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I5395
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25921
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	1	1.000	-	-		FOG0003851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.910