Protein Alignment mthl12 and ADGRD1

DIOPT Version :9

• Sequence 1: NP_731791.2
• Gene: mthl12 / 261599
• FlyBaseID: FBgn0045442
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_001317426.1
• Gene: ADGRD1 / 283383
• HGNCID: 19893
• Length: 906
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 58/299 - (19%)
• Similarity: 103/299 - (34%)
• Gaps: 101/299 - (33%)

  Fly   220 LSVISVVGFILTLAVYLSVEKLRN-------------LLGKCLICSLFSMFMEYFIWTMDYFRLL 271
            |||:.:|..::|.||..||..:||             |:.:.|:  |.|            |||.
Human   608 LSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLL--LIS------------FRLE 658

  Fly   272 QSI--CSAAGYMKYFFSMSSYLWFSVVSFHLWELFTSL-NRHEPQYRFLIYNTFVWCTAAIPTVV 333
            ...  |.....:.::|.:|::.|..|...||:.:...: ...:.::|:  |....|   ..|.::
Human   659 PGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRY--YYGMGW---GFPLLI 718

  Fly   334 -IFSMNQMWENDPGKSEWLPLVGYFGCSVKDWNSSSWFYSHIPIVILNSFNVIMFVLTAIYIWKV 397
             |.|::...::             :|.|...|.|            |.|..:..||..|:::..|
Human   719 CIISLSFAMDS-------------YGTSNNCWLS------------LASGAIWAFVAPALFVIVV 758

  Fly   398 KKGV-------------KSFAQHDERNTTCLEFNVQTYIQFVRLFLIMGASWLLDQLTRLAEDSH 449
            ..|:             .::..|.:.:...|     |......|..|:|.||
Human   759 NIGILIAVTRVISQISADNYKIHGDPSAFKL-----TAKAVAVLLPILGTSW------------- 805

  Fly   450 LLLDTIVLN--------LTVYLNAAFGILIFVLLILKGS 480
             :...:.:|        :...||:..|:.||:...|..|
Human   806 -VFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNS 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl12	NP_731791.2	Methuselah_N	27..209	CDD:284145
ADGRD1	NP_001317426.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810