Protein Alignment mthl12 and mthl13

DIOPT Version :9

• Sequence 1: NP_731791.2
• Gene: mthl12 / 261599
• FlyBaseID: FBgn0045442
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_788325.2
• Gene: mthl13 / 246395
• FlyBaseID: FBgn0050018
• Length: 440
• Species: Drosophila melanogaster
• Alignment Length: 420
• Identity: 161/420 - (38%)
• Similarity: 245/420 - (58%)
• Gaps: 47/420 - (11%)

  Fly    88 CIRICCARKNILSNGECSDGVKNEIKLTMLDLTMQDILLTDPTLAELNMIPQYNSTELLILREQ- 151
            ||.|||.|||:::||.||  .|..:..|.|||   :|.|.|            ||||.|....|
  Fly    49 CIPICCPRKNMMANGGCS--FKEHLFRTKLDL---NIRLDD------------NSTEALYFNNQT 96

  Fly   152 -----FQPCDEIVSLKRDEYTILKDGSILLHTSAEILSNDQYCLYP-EIYSDFPETIRIINRRCY 210
                 |...||::.|:|||||:.|:|:|.:|:...|.:.::||.|| :|||||||||.||:.:..
  Fly    97 LLITSFWDIDEMMGLRRDEYTLYKNGTIYIHSDQSIQTKEEYCFYPHQIYSDFPETIWIISHKFS 161

  Fly   211 RNVMPGIAQLSVISVVGFILTLAVYLSVEKLRNLLGKCLICSLFSMFMEYFIWTMDYFRLLQSIC 275
            ....||..:|:..|::.:|:...:||.|::|||..|||::..:|.:|::|.||.||..|||...|
  Fly   162 SIESPGAFELASGSIICYIIIFGIYLFVKELRNDFGKCVMSCVFCLFLDYLIWLMDELRLLDDFC 226

  Fly   276 SAAGYMKYFFSMSSYLWFSVVSFHLWELFTSLNRHEPQYRFLIYNTFVWCTAAIPTVVIFSMNQM 340
            |..||:.:||..::.:|||::|:.:|:..||:...|.:.:|:.|:||.:..:|||..:|.|:||.
  Fly   227 SLTGYIMFFFDFANSVWFSIISYCIWKKITSVVSQENRDQFVFYSTFAYGISAIPLGIIISINQF 291

  Fly   341 WENDPGKSEWLPLVGYFGCSVKDWNSSSWFYSHIPIVILNSFNVIMFVLTAIYIWKVKKGVKSFA 405
            ||.|..|..||||||:..|||.|...|||.|..:|..|:.:.|:||||||..:|.|.|:.:.:..
  Fly   292 WEEDLRKWNWLPLVGFSRCSVDDCKRSSWVYYFVPYAIMCAINIIMFVLTIKHIMKTKRNLHNLT 356

  Fly   406 QHDERNTTCLE---FNVQTYIQFVRLFLIMGASWLLDQLTRLAEDSHLLLDTIVLNLTVY----- 462
            :..:||.||:.   .|.:.|:.|:|:..|||.:|:|           ::...|.:|.|.:
  Fly   357 KRPDRNETCVTVNFLNFELYLLFLRISGIMGVAWIL-----------IIFLLIEVNSTFWDIFGI 410

  Fly   463 ----LNAAFGILIFVLLILKGSTFKMIMER 488
                ::..|||::|||||.|.||.::::.:
  Fly   411 IIQQIHYGFGIILFVLLIFKRSTHQLLIAK 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl12	NP_731791.2	Methuselah_N	27..209	CDD:284145	55/127 (43%)
mthl13	NP_788325.2	Mth_Ecto	<49..158	CDD:299804	55/125 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449105
Domainoid	1	1.000	49	1.000	Domainoid score	I4416
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I5395
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	1	1.000	-	-		FOG0003851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900