| Sequence 1: | NP_731791.2 | Gene: | mthl12 / 261599 | FlyBaseID: | FBgn0045442 | Length: | 488 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001352934.1 | Gene: | ADGRL2 / 23266 | HGNCID: | 18582 | Length: | 1469 | Species: | Homo sapiens |
| Alignment Length: | 275 | Identity: | 62/275 - (22%) |
|---|---|---|---|
| Similarity: | 113/275 - (41%) | Gaps: | 60/275 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 220 LSVISVVGFIL----------TLAVYLSVEKLRNLLGKCLICSLFSMFMEYFIWTMDYFRLLQSI 274
Fly 275 -CSAAGYMKYFFSMSSYLWFSVVSFHLW----ELFTSLNRHEPQY---RFLIYNTFVWCTAAIPT 331
Fly 332 VVIFSMNQMWENDPGKSEWLPLVGYFGCSVKDWNSSSWFYSHIPIVILNSFNVIMFVLTAIYIWK 396
Fly 397 VKKGVKSFAQHDERNTTCLEFNVQTYI--QFVRLFLIMGASWLLDQLTRLAEDSHLLLDTIVL-N 458
Fly 459 LTVYLNAAFGILIFV 473 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| mthl12 | NP_731791.2 | Methuselah_N | 27..209 | CDD:429053 | |
| 7tmB3_Methuselah-like | 220..488 | CDD:410632 | 62/275 (23%) | ||
| TM helix 2 | 246..268 | CDD:410632 | 6/21 (29%) | ||
| TM helix 3 | 276..303 | CDD:410632 | 4/30 (13%) | ||
| TM helix 4 | 316..336 | CDD:410632 | 6/19 (32%) | ||
| TM helix 5 | 364..394 | CDD:410632 | 8/29 (28%) | ||
| TM helix 6 | 410..444 | CDD:410632 | 8/35 (23%) | ||
| TM helix 7 | 449..479 | CDD:410632 | 9/26 (35%) | ||
| ADGRL2 | NP_001352934.1 | Gal_Rha_Lectin_LPHN2 | 36..132 | CDD:438702 | |
| OLF | 142..398 | CDD:470611 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 426..460 | ||||
| HormR | 469..533 | CDD:214468 | |||
| GAIN | 542..764 | CDD:465137 | |||
| GPS | 788..840 | CDD:197639 | |||
| GPS. /evidence=ECO:0000255|PROSITE-ProRule:PRU00098 | 792..841 | ||||
| 7tmB2_Latrophilin-2 | 848..1105 | CDD:320672 | 62/275 (23%) | ||
| TM helix 1 | 850..875 | CDD:320672 | 6/23 (26%) | ||
| TM helix 2 | 884..906 | CDD:320672 | 7/24 (29%) | ||
| TM helix 3 | 915..942 | CDD:320672 | 4/26 (15%) | ||
| TM helix 4 | 954..974 | CDD:320672 | 4/19 (21%) | ||
| TM helix 5 | 991..1020 | CDD:320672 | 10/39 (26%) | ||
| TM helix 6 | 1036..1063 | CDD:320672 | 6/34 (18%) | ||
| TM helix 7 | 1067..1092 | CDD:320672 | 8/20 (40%) | ||
| Latrophilin | 1104..1469 | CDD:460538 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1368..1410 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||