Protein Alignment mthl12 and adgre9

DIOPT Version :9

• Sequence 1: NP_731791.2
• Gene: mthl12 / 261599
• FlyBaseID: FBgn0045442
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: XP_021333151.1
• Gene: adgre9 / 101883848
• ZFINID: ZDB-GENE-121214-61
• Length: 660
• Species: Danio rerio
• Alignment Length: 391
• Identity: 81/391 - (20%)
• Similarity: 149/391 - (38%)
• Gaps: 78/391 - (19%)

  Fly   109 KNEIKL---TMLDLTM---QDILLTDPTLAELNMIPQYNSTELLILREQFQPCDEIVSLKRDEYT 167
            :|.:|.   |::..|:   .:..||.|....|..|..:|....|          ..|.....|:.
Zfish   294 ENTVKTMMSTVISATLSQTNNTALTKPVNFTLKHIQGFNPKSSL----------SCVYWNDSEWI 348

  Fly   168 ILKDGSILL-----HTSAEILSNDQYCLYPEIYSDFPET---IRIINRRCYRNVMPGIAQLSVIS 224
            :  ||..:|     ||....:....:.|..:..|..||:   :.::|..|.           ::.
Zfish   349 V--DGCSVLNSNSSHTVCSCVHLSTFALIMQTSSTPPESSDLLELLNLVCV-----------IVG 400

  Fly   225 VVGFILTLAVYLSVEKLR-----NLLGKCLIC-SLFSMFMEYFIWTMDYFRLL---QSICSAAGY 280
            :|.|.|.|   ||....:     |.:.:..|| ||.|..: .|:.|..:..|:   |..|.|...
Zfish   401 LVFFSLAL---LSFALCQWSPGVNNVARINICISLLSAHL-LFLLTQQFLSLIRPQQVFCVAIAG 461

  Fly   281 MKYFFSMSSYLWFSVVSFHLWELFTSLNRHEPQYRFLIYNTFVWCTAAIPTVVIFSMNQMWENDP 345
            :.:|..:|:::|..:.:..|:....:|:|...:.:.::.:.|:.....:..:|:.
Zfish   462 LLHFLFLSAFVWMFIEAVLLFICVQNLSRISSKKKEVLSSGFLCVIGYVLALVVV---------- 516

  Fly   346 GKSEWLPLVGYFG--CSVKDWNSSSWFYSHIPIVILNSFNVIMFVLTAIYIWKVKKGVKSFAQHD 408
            |.|..|...||..  |.:|......|.:.. |:.::.:.|.|.|:...:.:....|.:.:... .
Zfish   517 GVSIGLVPEGYGSEQCWIKTAEGFIWSFLG-PVCVILALNTIFFIKIVLTLNSTLKNLNAEVS-Q 579

  Fly   409 ERNTTCLEFNVQTYIQFVRLFLIMGASWLLDQLTRLAEDSHLLLDTIVLNLTVYLNAAFGILIFV 473
            .:.|..|.|  :|..|||    ::|..|:|......:|...:|.        :.||:..|..|||
Zfish   580 MKQTKILAF--KTLSQFV----VLGCPWILGFFINGSEVLEILF--------LVLNSQQGTFIFV 630

  Fly   474 L 474
            :
Zfish   631 I 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl12	NP_731791.2	Methuselah_N	27..209	CDD:284145	23/113 (20%)
adgre9	XP_021333151.1	GPS	335..380	CDD:197639	9/56 (16%)
		7tm_GPCRs	389..648	CDD:333717	59/284 (21%)
		TM helix 1	389..413	CDD:320095	8/37 (22%)
		TM helix 2	422..443	CDD:320095	6/21 (29%)
		TM helix 3	457..479	CDD:320095	4/21 (19%)
		TM helix 4	503..519	CDD:320095	3/25 (12%)
		TM helix 5	537..560	CDD:320095	4/23 (17%)
		TM helix 6	584..609	CDD:320095	9/30 (30%)
		TM helix 7	611..636	CDD:320095	8/29 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810