|
Human 135 SLATVFPSPSSDLEIPGTYTFNGSQVLARILGLEKL--LKQNSTSEDIRRELC------------ 185
:|...:| .|:|.....|...|..|.::|||..: |....:.|::.|.|.
Zfish 3384 ALLEAYP---EDIEKVTRSTVMISDSLIQLLGLSNISALPNGQSVEEVTRPLILSSAVATHILFN 3445
Human 186 DSYSGYIVDDAFSWTFLGRNVFNKF---------------------CLSNMTLLESSLQELNKQF 229
.|.|.|.:........|....||:. .|||: ||..|:...|
Zfish 3446 LSRSNYSLSSNVEKDMLLTQTFNQMMGVLPGESHVYLFAIKSALFDALSNV----SSTSEIQSHF 3506
Human 230 SQLSSDPNNQKIVFQEIVRMLS---------------FFSQVQEQKAVWQLLSSFPNVFQNDTSL 279
.::| :||.|.::..|: ....|..|.: :|.:..:..|.:.|
Zfish 3507 PEIS------QIVTQSLLNSLNITYDPKSMTPDGIVYILMTVSNQVS----MSLYEGLMLNGSPL 3561
Human 280 SNLFDVLRKANSVLLVVQKVYP-----------------RFATNEG--FRTLQKSVK-------- 317
.:.:|:...|.|...:..:.| .||.|:. |..|:.:|.
Zfish 3562 -QISEVVNSLNEVAFTLYSILPVEGRMYINITLNLMETLDFALNDNNTFGDLEGAVSQVVNSVNV 3625
Human 318 ------HLLYTLDSPAQGDSD----NITHVWNEDDGQTLSPSSLAAQLL---------------- 356
|:..:..|...||.: .|..:...|.......:.:..|||
Zfish 3626 LLDMVPHINTSYSSSIIGDLEQTLKTILMIIQADQSPVSQTADITQQLLQTIQNLITLGNSSSVE 3690
Human 357 ---------ILENFEDALLNIS---------------ANS--PYIPYLACVRNVTDSLARGSPEN 395
...|..|.||.:: ||| ..:||.:.::....|||..|.||
Zfish 3691 PELAKIVLGAASNDIDPLLGMNDTNWTDKLSVLVTNFANSLPDDLPYSSFIKTTMRSLANESQEN 3755
Human 396 LRLLQSTIRFKKSFL----RNGSYEDYFPPVPEVLKSKLSQLRNLTELLCESETFSLIEKSCQLS 456
|.||...:.....|: .|||.. ::|.|.|:| :|..|..:.:::..|..
Zfish 3756 LHLLLQVLNTSLEFVSANGANGSSS-------QILDSLLTQ-------VCALENMTSVQQISQFL 3806
Human 457 DMSFGSLCEESEFDLQLLEAAELGTEIAASLLYHDNVISKKVRDLLTGDPSKINLNMD--QFLEQ 519
.:....||: .::.|.:....:..||..|...|...:.....||.|..|..:| ..|.|
Zfish 3807 PLGPRLLCD------TVVPAVQAVYVLTTSLGNHSVNIYDLIFQTFIGDLSTYNTGVDWTSILSQ 3865
Human 520 ALQMNYLENITQLIPIIEAMLHVNNSADASEKPGQLLEMFKNVEELKEDLRRTTGMSNRTIDKLL 584
.:.. |::.| ..:.:|.::.|..|..:|| ||.....||:.|.|......:..:|
Zfish 3866 IVGF----NVSSL-----KTISINITSPAEVKVSELL---KNTTLFVEDVERYTSFPPGVLQTVL 3918
Human 585 AIPIPDNRAEIISQVFWLHSCDTNITTPKLEDA----MKEFCNLSLSERSRQSYLIGLTLLHYLN 645
..|:|.:..:|:..:..|..| ::.::.:|:.| ...||:| |...|.|.:..|.:::
Zfish 3919 DSPLPSSNMQILVWLANLQQC-SDPSSLQLDPAGQAMFSAFCDL-----SDDWYTISILFLRHMD 3977
Human 646 IYNFTYKVFFPRKDQKPVEKMMELFIRLKEILNQMASGTHPLLDKMRSLKQMHLPRSVPLTQAMY 710
.....:::...:..|..|..|:|:...|..::|::....:.|.:.:.::.|::|..:... ..:.
Zfish 3978 TKAILFRLMLSQDIQDLVATMLEMVKFLTNMMNKLVPAINKLQEYLTNIGQLNLVANQEF-HGLV 4041
Human 711 RSNRMN-TPQGSFSTISQALCSQGITTEY-------LTAMLPSSQRPKGNHTKDFLTYKLTKEQI 767
|..|.. :.:.:|:|:|:|||..||.|.: :||..||.| .:| .:|::
Zfish 4042 RGKRSTISSKATFNTLSRALCKNGILTLFAITKVPIVTAADPSVQ---SDH---------KREEL 4094
Human 768 ASKYGIPINSTPFCFSLYKDIINMPAGPVIWAFLKPMLLGRILYAPYNPVTKAIMEKSNVTLRQL 832
..|:.||.:::|||.||:.|::|...|.|.||||||||||:|||:|..|:|:.||.|||.:|.|.
Zfish 4095 IEKFKIPHDASPFCMSLFLDMVNTTGGAVAWAFLKPMLLGQILYSPDTPMTREIMRKSNSSLHQF 4159
Human 833 AELREKSQEWMDKSPLFMNSFHLLNQAIPMLQNTLRNPFVQVFVKFSVGLDAVELLKQIDELDIL 897
.:|:..:.||::.|...:.|.::|.|.:|:|:|:|.:||||.|::...|:|...:...:::...:
Zfish 4160 GDLKLYASEWIESSSYVLQSANILTQTLPILKNSLNSPFVQNFIRTQTGIDVSGMSATLNQFSNM 4224
Human 898 RLKLENNIDIIDQLNTLSSLTVNISSCVLYDRIQAAKTIDEMEREAKRLYKSNELFGSVIFKLPS 962
.:.||.|..|:||:.|||.|.:|:||||.:||.:...:.||::::|::|.::.||:.|:|||||.
Zfish 4225 TVLLEKNKFIMDQITTLSVLMMNLSSCVNFDRYRGFNSTDELDKQAEKLAQNRELYASIIFKLPK 4289
Human 963 NRSWHRGYDSGNVFLPPVIKYTIRMSLKTAQTTRSLRTKIWAPGPHNSPSHNQIYGRAFIYLQDS 1027
..| ..|||.|.|||||:::....|...|...|....:.|.:..|.|.|.|:|||:|
Zfish 4290 ENS---------SSLPPNIDYTIRMNIENVMRTDRARNPFWVKDAYISATRTQRYSRGFVYLQES 4345
Human 1028 IERAIIELQTGRNSQEIAVQVQAIPYPCFMKDNFLTSVSYSLPIVLMVAWVVFIAAFVKKLVYEK 1092
|||||||:|||......|||:||.||||:.||.:|.|::::.|:.||::||:|||.||||||:|:
Zfish 4346 IERAIIEMQTGNAMDGPAVQMQAFPYPCYYKDEYLNSIAFAFPMALMISWVLFIAHFVKKLVHER 4410
Human 1093 DLRLHEYMKMMGVNSCSHFFAWLIESVGFLLVTIVILIIILKFGNILPKTNGFILFLYFSDYSFS 1157
:|||||||||||||..||||||||||..|||||::||.||||.|.|||:::||:||||..||.||
Zfish 4411 ELRLHEYMKMMGVNPISHFFAWLIESGAFLLVTVIILTIILKAGGILPRSDGFVLFLYLCDYGFS 4475
Human 1158 VIAMSYLISVFFNNTNIAALIGSLIYIIAFFPFIVLVTVENELSYVLKVFMSLLSPTAFSYASQY 1222
|:|:|:|:|.||:.||||.|.|||||:|:|||||||:.:|:.||:.:|..:||.|||.|||||||
Zfish 4476 VLAVSFLVSSFFDKTNIAGLSGSLIYVISFFPFIVLIHLEDNLSFSVKSALSLFSPTCFSYASQY 4540
Human 1223 IARYEEQGIGLQWENMYTSPVQDDTTSFGWLCCLILADSFIYFLIAWYVRNVFPGTYGMAAPWYF 1287
|||||:|..|:||.|||.||:..||:||||||.|:|.||.:||:|..|:|.||||.||:|.||||
Zfish 4541 IARYEKQEEGIQWSNMYISPLAGDTSSFGWLCWLLLIDSLVYFIIGIYIRMVFPGKYGIAVPWYF 4605
Human 1288 PILPSYWKERFGCAEVKPEK-SNGLMFTNIMMQNTNPSASKTSPEYMFSSNIEPEPKDLTVGVAL 1351
|:..|:|.:.|.|....|:| ..||:|||:|...::.:.||.....:... |.:...|.|||:|
Zfish 4606 PVTKSFWTDMFSCCSKTPKKIGRGLLFTNMMQDQSSMNKSKGKGSLVAKG--EEDFSGLPVGVSL 4668
Human 1352 HGVTKIYGSKVAVDNLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDL 1416
:|:||.||.:.|||||||:|||||:|||||.||||||||:|:|||||..:.|||.|||.|::..:
Zfish 4669 YGLTKTYGKRNAVDNLNLSFYEGHVTSLLGHNGAGKTTTMSLLTGLFAPTVGTIEVYGMDMQMFI 4733
Human 1417 HTVRKNMGVCMQHDVLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGT 1481
..|||.||||||:||||.:||||||||||..||.|||||:::.|:|.:.|.:|.:::||||||||
Zfish 4734 DDVRKEMGVCMQYDVLFDHLTTKEHLLLYAQIKAPHWTKQEVKEQVHKILMETDMHAHRHKRVGT 4798
Human 1482 LSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISKNKTARTIILSTHHLDEAEVL 1546
||||||||||||||.|||||:|:||||:|||||||||||||:|.::|..||||||||||||||||
Zfish 4799 LSGGMKRKLSISIAFIGGSRLVVLDEPTTGVDPCSRRSIWDIIIQHKQERTIILSTHHLDEAEVL 4863
Human 1547 SDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKKKSPNLNANAVCDTMAVTAMIQSHLPEAYL 1611
||||||||:|||:|||||||||:....||:||||||.. ..::....|...:...|.||||:|..
Zfish 4864 SDRIAFLERGGLKCCGSPFYLKDKLAKGYNLTLTKKVE-TADSKEKFDYEKLRDFIHSHLPDARQ 4927
Human 1612 KEDIGGELVYVLPPFSTKVSGAYLSLLRALDNGMGDLNIGCYGISDTTVEEVFLNLTKESQKNSA 1676
|:...|:|||.|||::.:.:..|.|||.:||..:..|::|||||||||:|||||.||::..:...
Zfish 4928 KDREMGDLVYALPPYTPQNASEYHSLLNSLDQNLDKLHLGCYGISDTTLEEVFLQLTRDDLEPKE 4992
Human 1677 MSLEHLTQKKIGNSNANGISTPDDLSVSSSNFTDRDDKILTRGERLDGFGLLLKKIMAILIKRFH 1741
.....:::..|.| :..::.|.||...::....:...||....:.||.|.:::::|:|:||.|
Zfish 4993 SETWSVSESVIEN---DMFASRDSLSEDCNSMYLGEKASLTGNSTVRGFALGVQRVIAMLLKRVH 5054
Human 1742 HTRRNWKGLIAQVILPIVFVTTAMGLGTLRNSSNSYPEIQISPSLYGTSEQTAFYANYHPSTEAL 1806
|:||:||||.:||:||::||..|||||::::....:|||.:||:||...||.||::|.:|:|..|
Zfish 5055 HSRRDWKGLFSQVLLPVLFVIAAMGLGSIKSDLQHFPEIVLSPALYHVDEQYAFFSNQNPNTSRL 5119
Human 1807 VSAMWDFPGIDNMCL-NTSDLQCLNKDSL--EKWNTSGEPITNFGVCSCSENVQECPKFNYSPPH 1868
|..|..:||||::|: :.:|..|..:.|. :.|.:.|.....|..|.||..||.||...|.||.
Zfish 5120 VDTMMSYPGIDHVCMTDPTDPVCKGRPSTGSQTWVSGGNSSATFTTCKCSNQVQSCPAQGYDPPR 5184
Human 1869 RRTYSSQVIYNLTGQRVENYLISTANEFVQKRYGGWSFGLPLTKDLRFDITGVPANRTLAKVWYD 1933
:|..|||::|||||..:||||::|||.|::.|||||.||.||..||:.|:..|||||||:||||:
Zfish 5185 KRCPSSQIVYNLTGVNIENYLLATANNFIRDRYGGWEFGKPLPIDLKMDMLDVPANRTLSKVWYN 5249
Human 1934 PEGYHSLPAYLNSLNNFLLRVNMSKYDAARHGIIMYSHPYPGVQDQEQATISSLIDILVALSILM 1998
.||:||:||||||||||.||.::......::.|.:.||||||....|...:..|:.|||||.:|.
Zfish 5250 SEGHHSMPAYLNSLNNFFLRSSLPPEKRYQYAISISSHPYPGQVQDEDLMVGGLVSILVALCVLT 5314
Human 1999 GYSVTTASFVTYVVREHQTKAKQLQHISGIGVTCYWVTNFIYDMVFYLVPVAFSIGIIAIFKLPA 2063
|||:.|||||.|.|:||.|.:|:||.||||....||:.||.|||..|::||..|:.::|.|:|||
Zfish 5315 GYSIMTASFVIYEVQEHHTGSKRLQQISGISEPFYWIINFFYDMALYMIPVVLSVVMVAAFQLPA 5379
Human 2064 FYSENNLGAVSLLLLLFGYATFSWMYLLAGLFHETGMAFITYVCVNLFFGINSIVSLSVVYFLSK 2128
|....||.||:|||:|||::||.|||||:.:|.:|.||||.|||:|||..:|:|:|.|::|||.:
Zfish 5380 FTERQNLAAVTLLLVLFGFSTFPWMYLLSAMFKDTEMAFIGYVCINLFISVNTIISTSIIYFLGQ 5444
Human 2129 EKPNDPTLELISETLKRIFLIFPQFCFGYGLIELSQQQSVLDFLKAYGVEYPNETFEMNKLGAMF 2193
...||.:::.|.:|:..|||:||||.||.||:||::....:..|..:||:.....|.|:.||.||
Zfish 5445 LNQNDQSIQNIYQTMSNIFLVFPQFSFGNGLMELARVDMQVQILSGFGVDAYKNPFSMDVLGWMF 5509
Human 2194 VALVSQGTMFFSLRLLINESLIKKLRLFFRKFNSSHVRETIDEDEDVRAERLRVESGAAEFDLVQ 2258
:::..||.:.|:||||:|::|::|:|..|....::....:.:|||||..|||||..|.|..|::|
Zfish 5510 ISMFLQGFICFTLRLLLNKTLLRKVRRLFCWKRNAVQSYSPNEDEDVLDERLRVGRGDASSDILQ 5574
Human 2259 LYCLTKTYQLIHKKIIAVNNISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKT 2323
:..|||.||...|::.||.::|:||||||||||||||||||||.||||||||.||.|:..||:..
Zfish 5575 VNHLTKVYQNFSKRVQAVKSLSVGIPAGECFGLLGVNGAGKTTTFKMLTGDISPSGGSAKIRDID 5639
Human 2324 GSLGHVD-----SHSSLVGYCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLM 2383
|.: || .....:|||||.||||||:|.|||||||||:.||.::||.:.|:.||::|.|.
Zfish 5640 GRM--VDIIDCRREGINIGYCPQVDALDDLLTGEEHLYFYARIRGISKRDISQVVNYLLKKLQLN 5702
Human 2384 PFKDRATSMCSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILT 2448
..::..:...|.||:|||||||||||.|.|||||||||||||:|||||||||||:|..||:|:||
Zfish 5703 YHRNNTSESYSCGTRRKLSTALALIGNPQILLLDEPSSGMDPRSKRHLWKIISEQVMGKCAVVLT 5767
Human 2449 SHSMEECEALCTRLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNKVTMETLTKFMQLHFPK 2513
||||||||||||||||||.|:|:|:|||||||:|||.|||||::|......::.::.|||.:||.
Zfish 5768 SHSMEECEALCTRLAIMVKGQFRCLGSLQHIKNRFGSGFTVKMYLTGASYDVDMISNFMQQNFPG 5832
Human 2514 TYLKDQHLSMLEYHVPVTAGGVANIFDLLETNKTALNITNFLVSQTTLEEVFINFAKDQKSYETA 2578
|.|||.|.:|:||||||..||||:||.|||:|||.|.|.:|.||||||:||||||| ||
Zfish 5833 TCLKDNHSNMVEYHVPVAPGGVASIFSLLESNKTVLQIKHFSVSQTTLDEVFINFA-------TA 5890
Human 2579 DTSSQGSTISVDSQDDQMES 2598
...:.|...:..|..|.::|
Zfish 5891 KVDTDGLEATEGSDIDSLDS 5910
| 
