Protein Alignment ABCA12 and SPOM_SPAC323.04

DIOPT Version :10

• Sequence 1: XP_011509253.1
• Gene: ABCA12 / 26154
• HGNCID: 14637
• Length: 2598
• Species: Homo sapiens
• Sequence 2: NP_594374.1
• Gene: SPOM_SPAC323.04 / 2543203
• PomBaseID: SPAC323.04
• Length: 487
• Species: Schizosaccharomyces pombe
• Alignment Length: 281
• Identity: 66/281 - (23%)
• Similarity: 128/281 - (45%)
• Gaps: 47/281 - (16%)

Human  1313 FTNIMMQNTNPSASKTSPEYMF------SSNIEPEP-----KDLTVG---VALHGVTKIYGSKVA 1363
            |...:::..|...:...|:..:      |:||..:|     |.:|:|   :::..:..:|..:..
pombe   215 FITHVLELKNKKITYQGPKEQYIPMTSHSTNIPVKPQMKKSKPITIGKPLISMEHLNCVYWGRKV 279

Human  1364 VDNLNLNFYEGHITSLLGPNGAGKTTTISMLTG----LFGASAGTIFVYGKDI----KTDLHTVR 1420
            :.::|....||...:|.|.||:||||.::.:.|    ||   |..|..:||.|    ...:..::
pombe   280 LSDINWTIREGERWALTGSNGSGKTTLLAYVVGDHPKLF---ASNIKFFGKSIGPGTGISIFDIQ 341

Human  1421 KNMGVC---------MQH---DVLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYS 1473
            :|:|.|         .||   :.|.|..:|        :..:|..|:.:| ..:...|::..|..
pombe   342 ENIGHCSPEIHNHFPKQHTCFEALLSAWST--------TFTIPKLTETRL-AAISSILEEFELKD 397

Human  1474 HRHKRVGTLSGGMKRKLSISIALIGGSRVVILDEPSTGVDPCSRRSIWDVIS-KNKTARTIILST 1537
            .:.|.:.::|.||:|.:....|::...|:|:||||..|||........:.:: |...::.:::.:
pombe   398 IKDKPLSSISVGMQRFILFCRAIVKQPRLVVLDEPFQGVDTKYVHMAHNYLNEKLSPSQAMVIIS 462

Human  1538 HHLDEAEVLSDRIAFLEQGGL 1558
            |:.||.....:|.|.::.|.|
pombe   463 HYEDELPACVNRRAHIDNGKL 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCA12	XP_011509253.1	rim_protein	7..>86	CDD:130324
		rim_protein	752..2579	CDD:130324	66/281 (23%)
SPOM_SPAC323.04	NP_594374.1	PRK10938	24..475	CDD:182852	62/271 (23%)