DRSC/TRiP Functional Genomics Resources

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Protein Alignment LRRC32 and CG32055

DIOPT Version :9

Sequence 1:NP_001122394.1 Gene:LRRC32 / 2615 HGNCID:4161 Length:662 Species:Homo sapiens
Sequence 2:NP_729599.1 Gene:CG32055 / 39188 FlyBaseID:FBgn0052055 Length:534 Species:Drosophila melanogaster


Alignment Length:629 Identity:165/629 - (26%)
Similarity:242/629 - (38%) Gaps:159/629 - (25%)


- Green bases have known domain annotations that are detailed below.


Human    36 QVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTAL-RHLDLSTNEISFLQPGAFQALTHL 99
            |||.||.:..|...|.:..:..||  .|.|...:..:..| |::..:...:..:.          
  Fly     5 QVLALLLLSGVFGKDLQECEDLGN--GSYLCREIESFEQLNRYVGKNWKSVKVVN---------- 57

Human   100 EHLSLAHNRLAMATALSAGGLGPLPRVTS---LDLSGNSLYSG---LLERLLGEAPSLHTLSLAE 158
            ||           |.:.....|.||.:::   ||||    .||   |.|:.|.:..:|..|:|..
  Fly    58 EH-----------TGIERAEDGELPGLSTLLQLDLS----ESGGVTLGEKGLQDFKALQKLNLTH 107

Human   159 NSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFS---LQQL 220
            ..|..|....|.:...:...|:..|.::.|......|...|.:.|.|.|.:..|...:   ::.|
  Fly   108 AQLDELKSEQFPNPSEMINFDVSYNDILAITTKLMSGFGNLVYANFSENLIAVIEPNAFRHMKNL 172

Human   221 RVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQ 285
            |.|||:.|..|.               :.|.||..|.|           |::|||.:|       
  Fly   173 RFLDLTTNYQEN---------------ITLGENANLRF-----------LSISNNNLR------- 204

Human   286 DSKGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNC 350
            |.:..|.                   |.|.:|..|.|..|.:|.:.......|.:|..||:|.|.
  Fly   205 DFQWCHL-------------------RVLPKLEELHLHSNWLEHLDMGIFYALPNLRVLNVSNNN 250

Human   351 LRTFEARRL-----GSLPCLMLLDLSHNALETLELGARA-LGSLRTLLLQGNALRDLPPYTFANL 409
            |  ||.:|.     |.:..|.|||.|.|.::.|:..... |..||||.|..|.:..:.|..|..|
  Fly   251 L--FEIKRTLFMAPGEIAPLELLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAFLGL 313

Human   410 ASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAF---LHTPLTEL 471
            :|||.|:||||::|..  ||:       .|:.:|:|..|.|..|.|:.|....|   :...|..|
  Fly   314 SSLQTLHLQGNKISIL--PDD-------VFANLTALEKLDLSKNNIQKLGLRVFGERILRKLIYL 369

Human   472 DLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLA---ENRLSHLPAWT 533
            |||:|...::...||..: ..::.|.|:.|.|:.|  ||..|..|::|.|.   ||||..:..  
  Fly   370 DLSNNYIADLHPLALSSM-PFIKELRLRRNRLVSL--DLRMFAPLRQLQLLTINENRLEEIDG-- 429

Human   534 QAVSLEVLD---------LRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSC-CGN---GWLAAQL 585
                 |:||         |.||..:.||..........||.:.|:|||..| |.:   .||    
  Fly   430 -----EILDTLDRLNHLELNNNRLTFLPDLKSSQNLLQLRNITLEGNPWQCLCLDEITSWL---- 485

Human   586 HQGRVDVDATQDLICRFSSQEEVSLSHVRPEDCEKGGLKNINLI 629
             .||                   .:|:.||......|.|.:.::
  Fly   486 -NGR-------------------HVSYARPSSAYFSGRKPLCVV 509

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LRRC32NP_001122394.1 LRR_RI 19..277 CDD:238064 59/250 (24%)
leucine-rich repeat 31..50 CDD:275380 6/13 (46%)
PLN00113 49..>574 CDD:215061 148/555 (27%)
LRR 1. /evidence=ECO:0000255 50..73 5/22 (23%)
leucine-rich repeat 51..74 CDD:275380 4/22 (18%)
LRR 2. /evidence=ECO:0000255 74..95 2/21 (10%)
leucine-rich repeat 75..98 CDD:275380 2/23 (9%)
LRR 3. /evidence=ECO:0000255 98..119 3/20 (15%)
leucine-rich repeat 99..125 CDD:275380 5/25 (20%)
LRR 4. /evidence=ECO:0000255 125..145 8/25 (32%)
leucine-rich repeat 126..150 CDD:275380 9/29 (31%)
LRR 5. /evidence=ECO:0000255 150..171 6/20 (30%)
leucine-rich repeat 151..174 CDD:275380 6/22 (27%)
LRR 6. /evidence=ECO:0000255 174..195 3/20 (15%)
leucine-rich repeat 175..198 CDD:275380 4/22 (18%)
LRR 7. /evidence=ECO:0000255 198..219 5/23 (22%)
leucine-rich repeat 199..219 CDD:275380 5/22 (23%)
leucine-rich repeat 220..244 CDD:275380 7/23 (30%)
LRR 8. /evidence=ECO:0000255 220..240 7/19 (37%)
LRR 9. /evidence=ECO:0000255 244..265 5/20 (25%)
leucine-rich repeat 245..266 CDD:275380 5/20 (25%)
LRR 10. /evidence=ECO:0000255 266..286 5/19 (26%)
LRR 11. /evidence=ECO:0000255 316..339 5/22 (23%)
leucine-rich repeat 317..340 CDD:275380 6/22 (27%)
LRR 12. /evidence=ECO:0000255 340..363 10/27 (37%)
leucine-rich repeat 341..364 CDD:275380 10/27 (37%)
LRR 13. /evidence=ECO:0000255 364..385 7/21 (33%)
leucine-rich repeat 365..387 CDD:275380 8/22 (36%)
LRR 14. /evidence=ECO:0000255 387..408 8/20 (40%)
leucine-rich repeat 388..411 CDD:275380 9/22 (41%)
LRR 15. /evidence=ECO:0000255 411..432 11/20 (55%)
leucine-rich repeat 412..444 CDD:275380 11/31 (35%)
LRR 16. /evidence=ECO:0000255 444..465 7/23 (30%)
leucine-rich repeat 445..463 CDD:275380 6/17 (35%)
LRR 17. /evidence=ECO:0000255 467..488 8/20 (40%)
leucine-rich repeat 468..492 CDD:275380 8/23 (35%)
LRR 18. /evidence=ECO:0000255 492..513 7/20 (35%)
leucine-rich repeat 493..515 CDD:275380 8/21 (38%)
PLN03150 <496..654 CDD:178695 40/150 (27%)
LRR 19. /evidence=ECO:0000255 515..536 7/23 (30%)
leucine-rich repeat 516..537 CDD:275380 7/23 (30%)
LRR 20. /evidence=ECO:0000255 537..558 8/29 (28%)
leucine-rich repeat 538..559 CDD:275380 8/29 (28%)
leucine-rich repeat 563..575 CDD:275378 6/11 (55%)
CG32055NP_729599.1 leucine-rich repeat 76..99 CDD:275380 9/26 (35%)
leucine-rich repeat 100..123 CDD:275380 6/22 (27%)
LRR_8 128..180 CDD:290566 14/51 (27%)
leucine-rich repeat 128..147 CDD:275380 4/18 (22%)
leucine-rich repeat 148..171 CDD:275380 5/22 (23%)
leucine-rich repeat 172..192 CDD:275380 10/34 (29%)
LRR_RI <187..400 CDD:238064 78/261 (30%)
LRR_8 192..251 CDD:290566 22/95 (23%)
leucine-rich repeat 193..216 CDD:275380 11/59 (19%)
leucine-rich repeat 217..240 CDD:275380 6/22 (27%)
leucine-rich repeat 241..267 CDD:275380 10/27 (37%)
leucine-rich repeat 268..291 CDD:275380 8/22 (36%)
LRR_8 290..350 CDD:290566 26/68 (38%)
leucine-rich repeat 292..315 CDD:275380 9/22 (41%)
leucine-rich repeat 316..339 CDD:275380 11/31 (35%)
LRR_8 340..400 CDD:290566 18/60 (30%)
leucine-rich repeat 340..365 CDD:275380 7/24 (29%)
leucine-rich repeat 366..389 CDD:275380 8/23 (35%)
leucine-rich repeat 390..413 CDD:275380 9/24 (38%)
LRR_8 391..448 CDD:290566 21/65 (32%)
leucine-rich repeat 414..437 CDD:275380 9/29 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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