Protein Alignment TTLL3 and TTLL1A

DIOPT Version :9

• Sequence 1: NP_001021100.3
• Gene: TTLL3 / 26140
• HGNCID: 24483
• Length: 915
• Species: Homo sapiens
• Sequence 2: NP_573197.2
• Gene: TTLL1A / 32704
• FlyBaseID: FBgn0030823
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 134/503 - (26%)
• Similarity: 208/503 - (41%)
• Gaps: 124/503 - (24%)

Human   281 DKKAFIEDF----WLTAARNVLKLVVKSEWKSYPIQAVEEEAS---GDKQPKKQEKNPVLVS-PE 337
            ||.|.:.:|    ||....      ...||..|  .|..:...   |...|.:...:.|:.. |.
  Fly    63 DKSALVSNFQKRGWLQVPS------FNGEWNFY--WACTQNCRYIFGIDHPYRMRSDQVINHFPN 119

Human   338 FVDEALCACEEYLSNLAHMDIDKDLEA---PLYLT-PEGWSLFLQRYYQVVHEGAELRHLDTQVQ 398
            .::  |...:..:.|:..  ..||||.   ||..: |....|.:        .|...:|||
  Fly   120 SIE--LSRKDLLIKNIKR--YRKDLERRGDPLAQSHPPDTKLGI--------GGTRYKHLD---- 168

Human   399 RCEDILQQLQAVVP-------QIDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLV----NGN 452
                 :..:..|:|       ::......:.|||||.:||:|.||..::.|.::.|..    ...
  Fly   169 -----IIPMTFVLPSDYQMFVEVFHRNPASTWIVKPCSKSQGVGIYLVNKLSKLKKFAYDARTFY 228

Human   453 PVVMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDN- 516
            |.:.:| ..|:.|||:.||||.|.|||||.:.|||.:|||..:.|::.:.||.|:.:....:||
  Fly   229 PQINRD-TCVISKYIDNPLLIGGKKFDLRLFVLVTTFNPLKAYLYKEGFCRFCTEKYDETEIDNV 292

Human   517 SVHLCNNSIQKHLE--NSCH--RHPLLPPDNMWSSQRFQAHLQEMGAPN-AWSTIIVPGMKDAVI 576
            .:||.|.||||..:  ||.|  :.||   .|:|   .:...|:..|..: .||.|..     .:.
  Fly   293 FMHLTNVSIQKTNQEYNSIHGGKWPL---QNLW---LYLDSLRGEGVSDMLWSRITA-----TIR 346

Human   577 HALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVV 641
            |:|......:...:..||:||.|.:...:.:|||||||.||:| .||....|:......|.   |
  Fly   347 HSLDAVAPVMANDRHCFEVYGYDIIIDNNLKPWLIEINTSPSM-HSTTTNDRMLKSRLIDN---V 407

Human   642 IDRMLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGFTIKKPMAMCHRRMGVRPAVPLLTQRGS 706
            :|.::..||...  |...|.|..|         |::.||:..|::.|      :|
  Fly   408 LDVVVPPNCMPN--EHWDKTPNPE---------LLKNFTVLMPISPC------KP---------- 445

Human   707 GEARHHFPSLHTKAQLPSPHVLRHQGQVLRRQHSKLVGTKALSTTGKA 754
                        |.|:|    :|.:|::.:::.||       |||..:
  Fly   446 ------------KEQVP----VRRKGRLSKKKKSK-------STTASS 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3	NP_001021100.3	TTL	356..648	CDD:281171	96/312 (31%)
TTLL1A	NP_573197.2	TTL	107..419	CDD:281171	102/348 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2157
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810