Protein Alignment CG8176 and RGD2

DIOPT Version :9

• Sequence 1: NP_001097723.1
• Gene: CG8176 / 261329
• FlyBaseID: FBgn0037702
• Length: 1220
• Species: Drosophila melanogaster
• Sequence 2: NP_428268.1
• Gene: RGD2 / 850497
• SGDID: S000001847
• Length: 714
• Species: Saccharomyces cerevisiae
• Alignment Length: 439
• Identity: 91/439 - (20%)
• Similarity: 159/439 - (36%)
• Gaps: 145/439 - (33%)

  Fly     3 VDFNDYFWGEK-NNGYDVLYHNMKFG---------LIASK---ELSEFLREKSNIEE--QNSKMM 52
            :.|.||||.|. .:|.|||:..:..|         |.||:   |:|.. |:...||.  .|.|.:
Yeast     2 LSFCDYFWSEDLVSGLDVLFDRLYHGCEQCDLFIQLFASRMQFEVSHG-RQLFGIEAGMDNLKAV 65

  Fly    53 SKLAHKAGTLNSTFAPVWTILRTSAEKLS---TLHLQMVQKLTELV-KDVAKYADELHKKHKSVK 113
            .:...:..|::..       ||...:::|   |.||.:...:..|| :..:|:..| |::.  ::
Yeast    66 QEDEDEGVTVSRA-------LRGILQEMSQEGTHHLTIASNIESLVLQPFSKWCIE-HRER--IQ 120

  Fly   114 EEESQTLECVQAIQTSTVAVQKLRDLYASKVQELEKLRKDNGSHKDAEKLESKLKKLQEEYKALL 178
            ..|...|..|...:.|...|.||...|.:|.::||:.::   :|.:.::|.:.:|.|:
Yeast   121 YSEKTLLTNVNNFRKSKKYVGKLEKEYFNKCRQLEEFKR---THFNEDELANAMKSLK------- 175

  Fly   179 DKHNPIKNEFERRMTQTCKRFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMS 243
                 |:|::|             |:|...:...|.           :.:..:..|:|..
Yeast   176 -----IQNKYE-------------EDVAREKDHRFF-----------NRIAGIDFDYKTM----- 206

  Fly   244 VDKLLEQFVLNKYTGLEKPEMPELEYVALSSGSRLQQPQVSASASNSNSATSIQAALRAGNAATT 308
              |...|.:|.|        :|:.:|         :.|.:|.|.||:|:...|...|       .
Yeast   207 --KETLQLLLTK--------LPKTDY---------KLPLISYSLSNTNNGGEITKFL-------L 245

  Fly   309 ASGSAVSMDQR---GDALAAISLGSGSAASG------------------SIPFAEDPILGAMGSP 352
            ...|...:||.   |..|  ::||.....:|                  :..||..|:.|:
Yeast   246 DHMSLKDIDQAETFGQDL--LNLGFLKYCNGVGNTFVNSKKFQYQWKNTAYMFANVPMPGS---- 304

  Fly   353 RPTSPDMLAGANASGIQSQPTGGATSTVKSLRSWFLPTAKQQPSAGAGN 401
                             .:||.| .|.:....:|...:||:...:..||
Yeast   305 -----------------EEPTTG-ESLISRFNNWDGSSAKEIIQSKIGN 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332	56/276 (20%)
		Apolipoprotein	52..214	CDD:279749	32/165 (19%)
		AP_Syp1_like_MHD	928..1194	CDD:271171
RGD2	NP_428268.1	FCH	6..96	CDD:214492	27/97 (28%)
		DEP_fRgd2	205..289	CDD:239883	22/116 (19%)
		RhoGAP_fRGD2	473..708	CDD:239864

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23065
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010